TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
ZNF507 | CT | Colorectum | CRC | AP000787.1,MKKS,UNC50, etc. | 1.09e-02 | ![The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression.](images/gene_regulatory/Colorectum/Str/TF_CRC/regulons_activity_in_dotplot.png) |
ZNF507 | TFH | Colorectum | AD | COX20,ARID5A,UBXN2A, etc. | 0.00e+00 | ![The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression.](images/gene_regulatory/Colorectum/Str/TF_AD/regulons_activity_in_dotplot.png) |
ZNF507 | BN | Colorectum | AD | COX20,ARID5A,UBXN2A, etc. | 0.00e+00 | ![The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression.](images/gene_regulatory/Colorectum/Str/TF_AD/regulons_activity_in_dotplot.png) |
ZNF507 | ILC | Colorectum | ADJ | COX20,ARID5A,UBXN2A, etc. | 1.43e-02 | ![The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression.](images/gene_regulatory/Colorectum/Str/TF_ADJ/regulons_activity_in_dotplot.png) |
ZNF507 | TFH | Colorectum | CRC | COX20,ARID5A,UBXN2A, etc. | 0.00e+00 | ![The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression.](images/gene_regulatory/Colorectum/Str/TF_CRC/regulons_activity_in_dotplot.png) |
ZNF507 | BN | Colorectum | CRC | COX20,ARID5A,UBXN2A, etc. | 7.54e-02 | ![The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression.](images/gene_regulatory/Colorectum/Str/TF_CRC/regulons_activity_in_dotplot.png) |
ZNF507 | TH1 | Colorectum | CRC | COX20,ARID5A,UBXN2A, etc. | -2.22e-16 | ![The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression.](images/gene_regulatory/Colorectum/Str/TF_CRC/regulons_activity_in_dotplot.png) |
ZNF507 | TH17 | Colorectum | FAP | COX20,ARID5A,UBXN2A, etc. | 4.69e-02 | ![The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression.](images/gene_regulatory/Colorectum/Str/TF_FAP/regulons_activity_in_dotplot.png) |
ZNF507 | CD8TEXINT | Colorectum | FAP | COX20,ARID5A,UBXN2A, etc. | 1.52e-02 | ![The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression.](images/gene_regulatory/Colorectum/Str/TF_FAP/regulons_activity_in_dotplot.png) |
ZNF507 | ILC | Colorectum | FAP | COX20,ARID5A,UBXN2A, etc. | 1.52e-02 | ![The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression.](images/gene_regulatory/Colorectum/Str/TF_FAP/regulons_activity_in_dotplot.png) |
Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
ZNF507 | SNV | Missense_Mutation | novel | c.2524N>A | p.Gln842Lys | p.Q842K | Q8TCN5 | protein_coding | tolerated(0.91) | benign(0.001) | TCGA-AN-A046-01 | Breast | breast invasive carcinoma | Female | >=65 | I/II | Unknown | Unknown | SD |
ZNF507 | SNV | Missense_Mutation | novel | c.1654N>A | p.Asp552Asn | p.D552N | Q8TCN5 | protein_coding | tolerated(0.16) | benign(0) | TCGA-PE-A5DD-01 | Breast | breast invasive carcinoma | Female | <65 | I/II | Chemotherapy | | CR |
ZNF507 | insertion | Nonsense_Mutation | novel | c.1025_1026insTTTTATTTAATTTCATTTATATAGTACTTTCCCAAATTCAAT | p.Ala342_Glu343insPheIleTerPheHisLeuTyrSerThrPheProAsnSerIle | p.A342_E343insFI*FHLYSTFPNSI | Q8TCN5 | protein_coding | | | TCGA-A7-A0CJ-01 | Breast | breast invasive carcinoma | Female | <65 | I/II | Chemotherapy | cytoxan | SD |
ZNF507 | insertion | Frame_Shift_Ins | novel | c.74_75insAACAGCCATGATTCACCACC | p.Ser25ArgfsTer27 | p.S25Rfs*27 | Q8TCN5 | protein_coding | | | TCGA-A8-A090-01 | Breast | breast invasive carcinoma | Female | >=65 | I/II | Unknown | Unknown | SD |
ZNF507 | insertion | Frame_Shift_Ins | novel | c.792_793insGTACTTTCCCAAATTCAATATGCCCTGTACAAACTACATG | p.Thr265ValfsTer24 | p.T265Vfs*24 | Q8TCN5 | protein_coding | | | TCGA-A8-A09X-01 | Breast | breast invasive carcinoma | Female | <65 | III/IV | Unknown | Unknown | SD |
ZNF507 | insertion | Nonsense_Mutation | novel | c.364_365insAAAATACTTAGATGAGATTACAGACA | p.Ala122GlufsTer4 | p.A122Efs*4 | Q8TCN5 | protein_coding | | | TCGA-AN-A0AL-01 | Breast | breast invasive carcinoma | Female | <65 | III/IV | Unknown | Unknown | SD |
ZNF507 | SNV | Missense_Mutation | | c.2858N>T | p.Asn953Ile | p.N953I | Q8TCN5 | protein_coding | deleterious_low_confidence(0) | benign(0.143) | TCGA-FU-A3HZ-01 | Cervix | cervical & endocervical cancer | Female | <65 | I/II | Chemotherapy | cisplatin | CR |
ZNF507 | SNV | Missense_Mutation | | c.2423N>G | p.His808Arg | p.H808R | Q8TCN5 | protein_coding | deleterious(0) | probably_damaging(0.997) | TCGA-A6-5665-01 | Colorectum | colon adenocarcinoma | Female | >=65 | I/II | Unknown | Unknown | PD |
ZNF507 | SNV | Missense_Mutation | | c.1751N>A | p.Ser584Asn | p.S584N | Q8TCN5 | protein_coding | deleterious(0) | probably_damaging(0.996) | TCGA-AD-6964-01 | Colorectum | colon adenocarcinoma | Male | <65 | III/IV | Chemotherapy | folfox | PD |
ZNF507 | SNV | Missense_Mutation | rs371931412 | c.1931N>A | p.Arg644His | p.R644H | Q8TCN5 | protein_coding | deleterious(0) | probably_damaging(0.998) | TCGA-AZ-6598-01 | Colorectum | colon adenocarcinoma | Female | >=65 | I/II | Unknown | Unknown | SD |