TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
ZNF429 | ICAF | Breast | IDC | ZNF431,PMP22,CDKN2C, etc. | 6.02e-03 | ![The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression.](images/gene_regulatory/Breast/Str/TF_IDC/regulons_activity_in_dotplot.png) |
ZNF429 | NK | Lung | AAH | HMGB1,RHOH,TMEM267, etc. | 9.91e-03 | ![The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression.](images/gene_regulatory/Lung/Str/TF_AAH/regulons_activity_in_dotplot.png) |
ZNF429 | PERI | Oral cavity | ADJ | RNF175,FAM150B,AC009501.4, etc. | 4.29e-02 | ![The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression.](images/gene_regulatory/OralCavity/Str/TF_ADJ/regulons_activity_in_dotplot.png) |
ZNF429 | MSC.MVA | Oral cavity | ADJ | RNF175,FAM150B,AC009501.4, etc. | 1.12e-02 | ![The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression.](images/gene_regulatory/OralCavity/Str/TF_ADJ/regulons_activity_in_dotplot.png) |
ZNF429 | FIB | Oral cavity | OSCC | RNF175,FAM150B,AC009501.4, etc. | 0.00e+00 | ![The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression.](images/gene_regulatory/OralCavity/Str/TF_OSCC/regulons_activity_in_dotplot.png) |
ZNF429 | CAF | Oral cavity | OSCC | RNF175,FAM150B,AC009501.4, etc. | 0.00e+00 | ![The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression.](images/gene_regulatory/OralCavity/Str/TF_OSCC/regulons_activity_in_dotplot.png) |
ZNF429 | MYOFIB | Stomach | ADJ | BMP5,SRPX,DTNA, etc. | 1.95e-01 | ![The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression.](images/gene_regulatory/Stomach/Str/TF_ADJ/regulons_activity_in_dotplot.png) |
ZNF429 | ICAF | Stomach | ADJ | BMP5,SRPX,DTNA, etc. | 2.46e-02 | ![The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression.](images/gene_regulatory/Stomach/Str/TF_ADJ/regulons_activity_in_dotplot.png) |
ZNF429 | MYOFIB | Stomach | CAG with IM | BMP5,SRPX,DTNA, etc. | 1.40e-01 | ![The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression.](images/gene_regulatory/Stomach/Str/TF_CAG with IM/regulons_activity_in_dotplot.png) |
ZNF429 | SMC | Stomach | CSG | BMP5,SRPX,DTNA, etc. | 2.52e-01 | ![The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression.](images/gene_regulatory/Stomach/Str/TF_CSG/regulons_activity_in_dotplot.png) |
Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
ZNF429 | SNV | Missense_Mutation | novel | c.1833N>G | p.His611Gln | p.H611Q | Q86V71 | protein_coding | deleterious(0) | probably_damaging(0.999) | TCGA-A7-A6VX-01 | Breast | breast invasive carcinoma | Female | >=65 | I/II | Chemotherapy | docetaxel | CR |
ZNF429 | SNV | Missense_Mutation | novel | c.1478N>A | p.Ser493Tyr | p.S493Y | Q86V71 | protein_coding | tolerated(0.23) | possibly_damaging(0.756) | TCGA-AC-A3W6-01 | Breast | breast invasive carcinoma | Female | >=65 | III/IV | Unknown | Unknown | SD |
ZNF429 | SNV | Missense_Mutation | rs780017355 | c.659N>G | p.Lys220Arg | p.K220R | Q86V71 | protein_coding | tolerated(0.11) | benign(0.251) | TCGA-AR-A24N-01 | Breast | breast invasive carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
ZNF429 | SNV | Missense_Mutation | | c.82N>A | p.Leu28Ile | p.L28I | Q86V71 | protein_coding | deleterious(0) | probably_damaging(0.998) | TCGA-AR-A24Q-01 | Breast | breast invasive carcinoma | Female | <65 | I/II | Chemotherapy | doxorubicin | SD |
ZNF429 | SNV | Missense_Mutation | | c.989G>A | p.Ser330Asn | p.S330N | Q86V71 | protein_coding | tolerated(0.28) | benign(0.006) | TCGA-BH-A0AW-01 | Breast | breast invasive carcinoma | Female | <65 | I/II | Chemotherapy | carboplatin | SD |
ZNF429 | SNV | Missense_Mutation | | c.1180N>C | p.Glu394Gln | p.E394Q | Q86V71 | protein_coding | deleterious(0.03) | possibly_damaging(0.821) | TCGA-BH-A0HA-01 | Breast | breast invasive carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
ZNF429 | SNV | Missense_Mutation | | c.1759N>T | p.His587Tyr | p.H587Y | Q86V71 | protein_coding | deleterious(0.04) | possibly_damaging(0.79) | TCGA-C8-A12P-01 | Breast | breast invasive carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
ZNF429 | SNV | Missense_Mutation | | c.1852G>C | p.Glu618Gln | p.E618Q | Q86V71 | protein_coding | deleterious(0.01) | possibly_damaging(0.773) | TCGA-D8-A142-01 | Breast | breast invasive carcinoma | Female | >=65 | I/II | Chemotherapy | cyclophosphamid | SD |
ZNF429 | SNV | Missense_Mutation | novel | c.725N>T | p.Ser242Leu | p.S242L | Q86V71 | protein_coding | deleterious(0.03) | possibly_damaging(0.551) | TCGA-D8-A27V-01 | Breast | breast invasive carcinoma | Female | <65 | I/II | Hormone Therapy | tamoxiphen | SD |
ZNF429 | SNV | Missense_Mutation | rs879241367 | c.800N>A | p.Ser267Asn | p.S267N | Q86V71 | protein_coding | tolerated(1) | benign(0.001) | TCGA-2W-A8YY-01 | Cervix | cervical & endocervical cancer | Female | <65 | I/II | Chemotherapy | cisplatin | CR |