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Gene: RETREG2 |
Gene summary for RETREG2 |
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Gene information | Species | Human | Gene symbol | RETREG2 | Gene ID | 79137 |
Gene name | reticulophagy regulator family member 2 | |
Gene Alias | C2orf17 | |
Cytomap | 2q35 | |
Gene Type | protein-coding | GO ID | GO:0005575 | UniProtAcc | B3KR51 |
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Malignant transformation analysis |
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Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
79137 | RETREG2 | HTA11_3410_2000001011 | Human | Colorectum | AD | 6.14e-11 | 2.14e-01 | 0.0155 |
79137 | RETREG2 | HTA11_2487_2000001011 | Human | Colorectum | SER | 1.20e-08 | 3.77e-01 | -0.1808 |
79137 | RETREG2 | HTA11_1938_2000001011 | Human | Colorectum | AD | 9.44e-15 | 5.25e-01 | -0.0811 |
79137 | RETREG2 | HTA11_78_2000001011 | Human | Colorectum | AD | 2.41e-09 | 3.93e-01 | -0.1088 |
79137 | RETREG2 | HTA11_347_2000001011 | Human | Colorectum | AD | 4.95e-24 | 5.56e-01 | -0.1954 |
79137 | RETREG2 | HTA11_411_2000001011 | Human | Colorectum | SER | 1.13e-04 | 6.62e-01 | -0.2602 |
79137 | RETREG2 | HTA11_2112_2000001011 | Human | Colorectum | SER | 4.45e-03 | 3.69e-01 | -0.2196 |
79137 | RETREG2 | HTA11_3361_2000001011 | Human | Colorectum | AD | 4.23e-04 | 3.62e-01 | -0.1207 |
79137 | RETREG2 | HTA11_83_2000001011 | Human | Colorectum | SER | 5.26e-14 | 5.19e-01 | -0.1526 |
79137 | RETREG2 | HTA11_696_2000001011 | Human | Colorectum | AD | 1.31e-12 | 4.30e-01 | -0.1464 |
79137 | RETREG2 | HTA11_866_2000001011 | Human | Colorectum | AD | 2.86e-13 | 3.86e-01 | -0.1001 |
79137 | RETREG2 | HTA11_1391_2000001011 | Human | Colorectum | AD | 6.72e-22 | 6.37e-01 | -0.059 |
79137 | RETREG2 | HTA11_2992_2000001011 | Human | Colorectum | SER | 1.58e-04 | 4.90e-01 | -0.1706 |
79137 | RETREG2 | HTA11_5212_2000001011 | Human | Colorectum | AD | 6.48e-08 | 5.29e-01 | -0.2061 |
79137 | RETREG2 | HTA11_5216_2000001011 | Human | Colorectum | SER | 8.22e-05 | 5.06e-01 | -0.1462 |
79137 | RETREG2 | HTA11_546_2000001011 | Human | Colorectum | AD | 2.07e-06 | 3.86e-01 | -0.0842 |
79137 | RETREG2 | HTA11_7862_2000001011 | Human | Colorectum | AD | 2.21e-02 | 2.66e-01 | -0.0179 |
79137 | RETREG2 | HTA11_866_3004761011 | Human | Colorectum | AD | 5.22e-15 | 4.02e-01 | 0.096 |
79137 | RETREG2 | HTA11_7663_2000001011 | Human | Colorectum | SER | 9.78e-11 | 6.68e-01 | 0.0131 |
79137 | RETREG2 | HTA11_10623_2000001011 | Human | Colorectum | AD | 3.82e-04 | 3.14e-01 | -0.0177 |
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∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
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Malignant transformation related pathway analysis |
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Tissue | Disease Stage | Enriched GO biological Processes |
Esophagus | ESCC | ![]() |
Skin | AK | ![]() |
Skin | SCCIS | ![]() |
Skin | cSCC | ![]() |
Thyroid | HT | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
Page: 1 2 3 4 5 6 7 8 9 |
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GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
Page: 1 |
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Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
Page: 1 |
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Cell-cell communication analysis |
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Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
Page: 1 |
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Single-cell gene regulatory network inference analysis |
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TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
Page: 1 |
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Somatic mutation of malignant transformation related genes |
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Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
Page: 1 |
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Related drugs of malignant transformation related genes |
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(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
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