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Gene: EEF1AKMT2 |
Gene summary for EEF1AKMT2 |
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Gene information | Species | Human | Gene symbol | EEF1AKMT2 | Gene ID | 399818 |
Gene name | EEF1A lysine methyltransferase 2 | |
Gene Alias | C10orf138 | |
Cytomap | 10q26.13 | |
Gene Type | protein-coding | GO ID | GO:0006464 | UniProtAcc | Q5JPI9 |
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Malignant transformation analysis |
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Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
399818 | EEF1AKMT2 | LZE4T | Human | Esophagus | ESCC | 3.78e-08 | 2.32e-01 | 0.0811 |
399818 | EEF1AKMT2 | LZE5T | Human | Esophagus | ESCC | 1.00e-09 | 4.15e-01 | 0.0514 |
399818 | EEF1AKMT2 | LZE7T | Human | Esophagus | ESCC | 3.98e-06 | 2.31e-01 | 0.0667 |
399818 | EEF1AKMT2 | LZE8T | Human | Esophagus | ESCC | 4.41e-02 | 1.21e-01 | 0.067 |
399818 | EEF1AKMT2 | LZE20T | Human | Esophagus | ESCC | 3.16e-03 | 1.53e-01 | 0.0662 |
399818 | EEF1AKMT2 | LZE24T | Human | Esophagus | ESCC | 6.43e-22 | 5.12e-01 | 0.0596 |
399818 | EEF1AKMT2 | LZE21T | Human | Esophagus | ESCC | 9.73e-05 | 3.00e-01 | 0.0655 |
399818 | EEF1AKMT2 | LZE6T | Human | Esophagus | ESCC | 5.35e-04 | 2.04e-01 | 0.0845 |
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Tissue | Expression Dynamics | Abbreviation |
∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
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Malignant transformation related pathway analysis |
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Tissue | Disease Stage | Enriched GO biological Processes |
Esophagus | ESCC | ![]() |
Skin | AK | ![]() |
Skin | SCCIS | ![]() |
Skin | cSCC | ![]() |
Thyroid | HT | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
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GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
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Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
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Cell-cell communication analysis |
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Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
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Single-cell gene regulatory network inference analysis |
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TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
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Somatic mutation of malignant transformation related genes |
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Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
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Related drugs of malignant transformation related genes |
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(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
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