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Gene: CYBC1 |
Gene summary for CYBC1 |
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Gene information | Species | Human | Gene symbol | CYBC1 | Gene ID | 79415 |
Gene name | cytochrome b-245 chaperone 1 | |
Gene Alias | C17orf62 | |
Cytomap | 17q25.3 | |
Gene Type | protein-coding | GO ID | GO:0002252 | UniProtAcc | A0A024R8W9 |
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Malignant transformation analysis |
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Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
79415 | CYBC1 | LZE4T | Human | Esophagus | ESCC | 4.43e-16 | 3.80e-01 | 0.0811 |
79415 | CYBC1 | LZE5T | Human | Esophagus | ESCC | 1.57e-02 | 2.52e-01 | 0.0514 |
79415 | CYBC1 | LZE7T | Human | Esophagus | ESCC | 8.50e-13 | 5.35e-01 | 0.0667 |
79415 | CYBC1 | LZE8T | Human | Esophagus | ESCC | 1.75e-09 | 3.67e-01 | 0.067 |
79415 | CYBC1 | LZE20T | Human | Esophagus | ESCC | 1.30e-10 | 3.22e-01 | 0.0662 |
79415 | CYBC1 | LZE22D1 | Human | Esophagus | HGIN | 5.14e-03 | 2.01e-01 | 0.0595 |
79415 | CYBC1 | LZE22T | Human | Esophagus | ESCC | 8.47e-11 | 6.52e-01 | 0.068 |
79415 | CYBC1 | LZE24T | Human | Esophagus | ESCC | 6.97e-47 | 9.68e-01 | 0.0596 |
79415 | CYBC1 | LZE21T | Human | Esophagus | ESCC | 2.35e-14 | 6.57e-01 | 0.0655 |
79415 | CYBC1 | LZE6T | Human | Esophagus | ESCC | 2.95e-13 | 4.38e-01 | 0.0845 |
79415 | CYBC1 | S014 | Human | Liver | HCC | 4.48e-28 | 8.37e-01 | 0.2254 |
79415 | CYBC1 | S015 | Human | Liver | HCC | 1.80e-33 | 1.15e+00 | 0.2375 |
79415 | CYBC1 | S016 | Human | Liver | HCC | 1.02e-35 | 9.46e-01 | 0.2243 |
79415 | CYBC1 | S027 | Human | Liver | HCC | 3.99e-13 | 8.80e-01 | 0.2446 |
79415 | CYBC1 | S028 | Human | Liver | HCC | 5.19e-32 | 9.92e-01 | 0.2503 |
79415 | CYBC1 | S029 | Human | Liver | HCC | 5.23e-28 | 9.48e-01 | 0.2581 |
79415 | CYBC1 | male-WTA | Human | Thyroid | PTC | 1.29e-07 | 1.66e-01 | 0.1037 |
79415 | CYBC1 | PTC01 | Human | Thyroid | PTC | 5.11e-12 | 2.69e-01 | 0.1899 |
79415 | CYBC1 | PTC03 | Human | Thyroid | PTC | 1.79e-02 | 1.86e-01 | 0.1784 |
79415 | CYBC1 | PTC04 | Human | Thyroid | PTC | 2.77e-07 | 2.00e-01 | 0.1927 |
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∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
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Malignant transformation related pathway analysis |
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Tissue | Disease Stage | Enriched GO biological Processes |
Esophagus | ESCC | ![]() |
Skin | AK | ![]() |
Skin | SCCIS | ![]() |
Skin | cSCC | ![]() |
Thyroid | HT | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
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GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
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Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
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Cell-cell communication analysis |
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Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
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Single-cell gene regulatory network inference analysis |
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TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
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Somatic mutation of malignant transformation related genes |
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Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
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Related drugs of malignant transformation related genes |
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(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
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