GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
GO:001049810 | Cervix | CC | proteasomal protein catabolic process | 111/2311 | 490/18723 | 8.98e-11 | 1.58e-08 | 111 |
GO:004316110 | Cervix | CC | proteasome-mediated ubiquitin-dependent protein catabolic process | 91/2311 | 412/18723 | 1.65e-08 | 1.25e-06 | 91 |
GO:003497610 | Cervix | CC | response to endoplasmic reticulum stress | 57/2311 | 256/18723 | 5.81e-06 | 1.42e-04 | 57 |
GO:003497615 | Cervix | HSIL_HPV | response to endoplasmic reticulum stress | 20/737 | 256/18723 | 2.88e-03 | 2.70e-02 | 20 |
GO:0010498111 | Esophagus | ESCC | proteasomal protein catabolic process | 369/8552 | 490/18723 | 1.13e-41 | 1.80e-38 | 369 |
GO:0043161111 | Esophagus | ESCC | proteasome-mediated ubiquitin-dependent protein catabolic process | 312/8552 | 412/18723 | 3.53e-36 | 4.48e-33 | 312 |
GO:0034976111 | Esophagus | ESCC | response to endoplasmic reticulum stress | 192/8552 | 256/18723 | 7.15e-22 | 1.30e-19 | 192 |
GO:003650315 | Esophagus | ESCC | ERAD pathway | 82/8552 | 107/18723 | 5.80e-11 | 1.84e-09 | 82 |
GO:003043314 | Esophagus | ESCC | ubiquitin-dependent ERAD pathway | 66/8552 | 85/18723 | 1.64e-09 | 3.78e-08 | 66 |
GO:00091002 | Esophagus | ESCC | glycoprotein metabolic process | 226/8552 | 387/18723 | 2.64e-07 | 3.94e-06 | 226 |
GO:19011362 | Esophagus | ESCC | carbohydrate derivative catabolic process | 99/8552 | 172/18723 | 1.11e-03 | 5.54e-03 | 99 |
GO:00311461 | Esophagus | ESCC | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process | 33/8552 | 49/18723 | 1.80e-03 | 8.26e-03 | 33 |
GO:0006516 | Esophagus | ESCC | glycoprotein catabolic process | 19/8552 | 28/18723 | 1.49e-02 | 4.84e-02 | 19 |
GO:001603212 | Liver | Cirrhotic | viral process | 203/4634 | 415/18723 | 5.40e-27 | 3.76e-24 | 203 |
GO:004440312 | Liver | Cirrhotic | biological process involved in symbiotic interaction | 131/4634 | 290/18723 | 2.00e-14 | 1.84e-12 | 131 |
GO:00518171 | Liver | Cirrhotic | modulation of process of other organism involved in symbiotic interaction | 44/4634 | 81/18723 | 1.11e-08 | 4.26e-07 | 44 |
GO:005170211 | Liver | Cirrhotic | biological process involved in interaction with symbiont | 48/4634 | 94/18723 | 3.41e-08 | 1.14e-06 | 48 |
GO:00518511 | Liver | Cirrhotic | modulation by host of symbiont process | 33/4634 | 60/18723 | 5.09e-07 | 1.14e-05 | 33 |
GO:200037712 | Liver | Cirrhotic | regulation of reactive oxygen species metabolic process | 67/4634 | 157/18723 | 6.07e-07 | 1.32e-05 | 67 |
GO:00358213 | Liver | Cirrhotic | modulation of process of other organism | 49/4634 | 106/18723 | 1.20e-06 | 2.43e-05 | 49 |
Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
CRP | SNV | Missense_Mutation | | c.185C>G | p.Ser62Cys | p.S62C | P02741 | protein_coding | deleterious(0.01) | possibly_damaging(0.662) | TCGA-AC-A23H-01 | Breast | breast invasive carcinoma | Female | >=65 | I/II | Unknown | Unknown | PD |
CRP | SNV | Missense_Mutation | | c.148N>T | p.Ala50Ser | p.A50S | P02741 | protein_coding | tolerated(0.35) | benign(0.079) | TCGA-C8-A1HJ-01 | Breast | breast invasive carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
CRP | SNV | Missense_Mutation | | c.263N>G | p.Asp88Gly | p.D88G | P02741 | protein_coding | tolerated(0.42) | benign(0.003) | TCGA-D8-A1Y1-01 | Breast | breast invasive carcinoma | Female | >=65 | III/IV | Hormone Therapy | tamoxiphen | PD |
CRP | insertion | Frame_Shift_Ins | novel | c.448_449insCT | p.Ser150ThrfsTer29 | p.S150Tfs*29 | P02741 | protein_coding | | | TCGA-AO-A0JB-01 | Breast | breast invasive carcinoma | Female | <65 | III/IV | Chemotherapy | cyclophosphamide | SD |
CRP | insertion | In_Frame_Ins | novel | c.447_448insTGGGCCCCACGTCTCTGTCTCTGGTACCTCCCGCTTTTTTAC | p.Ala149_Ser150insTrpAlaProArgLeuCysLeuTrpTyrLeuProLeuPheTyr | p.A149_S150insWAPRLCLWYLPLFY | P02741 | protein_coding | | | TCGA-AO-A0JB-01 | Breast | breast invasive carcinoma | Female | <65 | III/IV | Chemotherapy | cyclophosphamide | SD |
CRP | SNV | Missense_Mutation | rs200949626 | c.643N>A | p.Glu215Lys | p.E215K | P02741 | protein_coding | tolerated(0.18) | possibly_damaging(0.68) | TCGA-AA-3950-01 | Colorectum | colon adenocarcinoma | Female | >=65 | I/II | Unknown | Unknown | SD |
CRP | SNV | Missense_Mutation | | c.314N>A | p.Pro105His | p.P105H | P02741 | protein_coding | tolerated(0.07) | possibly_damaging(0.797) | TCGA-EI-6882-01 | Colorectum | rectum adenocarcinoma | Male | <65 | I/II | Unknown | Unknown | SD |
CRP | SNV | Missense_Mutation | | c.283N>A | p.Val95Met | p.V95M | P02741 | protein_coding | deleterious(0) | probably_damaging(0.995) | TCGA-A5-A0VP-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | >=65 | I/II | Unknown | Unknown | SD |
CRP | SNV | Missense_Mutation | novel | c.350N>A | p.Ser117Asn | p.S117N | P02741 | protein_coding | deleterious(0.05) | benign(0.138) | TCGA-A5-A2K5-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | >=65 | I/II | Unknown | Unknown | SD |
CRP | SNV | Missense_Mutation | | c.334G>A | p.Val112Ile | p.V112I | P02741 | protein_coding | tolerated(0.27) | benign(0.033) | TCGA-AP-A051-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | >=65 | I/II | Unknown | Unknown | SD |