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Gene: SLMO2 |
Gene summary for SLMO2 |
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Gene information | Species | Human | Gene symbol | SLMO2 | Gene ID | 51012 |
Gene name | PRELI domain containing 3B | |
Gene Alias | C20orf45 | |
Cytomap | 20q13.32 | |
Gene Type | protein-coding | GO ID | GO:0006810 | UniProtAcc | Q9Y3B1 |
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Malignant transformation analysis |
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Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
51012 | SLMO2 | P1_S1_AK | Human | Skin | AK | 4.59e-09 | -2.08e-01 | -0.3399 |
51012 | SLMO2 | P2_S3_AK | Human | Skin | AK | 2.11e-09 | -2.08e-01 | -0.3287 |
51012 | SLMO2 | P2_S4_SCCIS | Human | Skin | SCCIS | 4.65e-08 | -2.08e-01 | -0.3043 |
51012 | SLMO2 | P3_S6_AK | Human | Skin | AK | 2.11e-09 | -2.08e-01 | -0.3256 |
51012 | SLMO2 | P5_S10_cSCC | Human | Skin | cSCC | 9.71e-10 | -2.08e-01 | -0.299 |
51012 | SLMO2 | P1_cSCC | Human | Skin | cSCC | 2.56e-19 | 7.03e-01 | 0.0292 |
51012 | SLMO2 | P2_cSCC | Human | Skin | cSCC | 1.26e-15 | 5.15e-01 | -0.024 |
51012 | SLMO2 | P4_cSCC | Human | Skin | cSCC | 4.76e-14 | 5.44e-01 | -0.00290000000000005 |
51012 | SLMO2 | P10_cSCC | Human | Skin | cSCC | 3.09e-29 | 9.70e-01 | 0.1017 |
51012 | SLMO2 | cSCC_p1 | Human | Skin | cSCC | 2.11e-09 | -2.08e-01 | -0.1916 |
51012 | SLMO2 | cSCC_p10 | Human | Skin | cSCC | 2.11e-09 | -2.08e-01 | -0.2095 |
51012 | SLMO2 | cSCC_p11 | Human | Skin | cSCC | 2.11e-09 | -2.08e-01 | -0.2102 |
51012 | SLMO2 | cSCC_p3 | Human | Skin | cSCC | 2.11e-09 | -2.08e-01 | -0.2085 |
51012 | SLMO2 | cSCC_p4 | Human | Skin | cSCC | 9.96e-07 | -2.08e-01 | -0.2022 |
51012 | SLMO2 | cSCC_p6 | Human | Skin | cSCC | 4.59e-09 | -2.08e-01 | -0.1989 |
51012 | SLMO2 | cSCC_p7 | Human | Skin | cSCC | 9.96e-07 | -2.08e-01 | -0.2332 |
51012 | SLMO2 | cSCC_p8 | Human | Skin | cSCC | 2.11e-09 | -2.08e-01 | -0.1971 |
51012 | SLMO2 | cSCC_p9 | Human | Skin | cSCC | 9.71e-10 | -2.08e-01 | -0.1991 |
51012 | SLMO2 | NAG_1 | Human | Stomach | CSG | 1.10e-21 | 6.84e-01 | -0.3534 |
51012 | SLMO2 | NAG_2 | Human | Stomach | CSG | 5.35e-16 | 5.76e-01 | -0.3324 |
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∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
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Malignant transformation related pathway analysis |
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Tissue | Disease Stage | Enriched GO biological Processes |
Oral cavity | OSCC | ![]() |
Oral cavity | LP | ![]() |
Oral cavity | EOLP | ![]() |
Oral cavity | NEOLP | ![]() |
Esophagus | HGIN | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
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GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
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Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
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Cell-cell communication analysis |
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Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
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Single-cell gene regulatory network inference analysis |
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TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
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Somatic mutation of malignant transformation related genes |
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Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
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Related drugs of malignant transformation related genes |
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(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
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