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Gene: RTL8A |
Gene summary for RTL8A |
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Gene information | Species | Human | Gene symbol | RTL8A | Gene ID | 26071 |
Gene name | retrotransposon Gag like 8A | |
Gene Alias | CXX1b | |
Cytomap | Xq26.3 | |
Gene Type | protein-coding | GO ID | GO:0005575 | UniProtAcc | Q9BWD3 |
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Malignant transformation analysis |
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Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
26071 | RTL8A | HTA11_2487_2000001011 | Human | Colorectum | SER | 4.81e-03 | 1.89e-01 | -0.1808 |
26071 | RTL8A | HTA11_347_2000001011 | Human | Colorectum | AD | 5.52e-07 | 2.48e-01 | -0.1954 |
26071 | RTL8A | HTA11_411_2000001011 | Human | Colorectum | SER | 4.29e-03 | 5.21e-01 | -0.2602 |
26071 | RTL8A | HTA11_3361_2000001011 | Human | Colorectum | AD | 3.23e-02 | 2.18e-01 | -0.1207 |
26071 | RTL8A | HTA11_83_2000001011 | Human | Colorectum | SER | 2.51e-03 | 2.67e-01 | -0.1526 |
26071 | RTL8A | HTA11_696_2000001011 | Human | Colorectum | AD | 1.86e-11 | 2.59e-01 | -0.1464 |
26071 | RTL8A | HTA11_866_2000001011 | Human | Colorectum | AD | 3.85e-05 | 1.91e-01 | -0.1001 |
26071 | RTL8A | HTA11_1391_2000001011 | Human | Colorectum | AD | 1.58e-08 | 3.43e-01 | -0.059 |
26071 | RTL8A | HTA11_2992_2000001011 | Human | Colorectum | SER | 1.11e-03 | 3.61e-01 | -0.1706 |
26071 | RTL8A | HTA11_5212_2000001011 | Human | Colorectum | AD | 1.97e-02 | 2.63e-01 | -0.2061 |
26071 | RTL8A | HTA11_7862_2000001011 | Human | Colorectum | AD | 6.50e-04 | 2.53e-01 | -0.0179 |
26071 | RTL8A | HTA11_4255_2000001011 | Human | Colorectum | SER | 8.35e-03 | 3.18e-01 | 0.0446 |
26071 | RTL8A | HTA11_6801_2000001011 | Human | Colorectum | SER | 2.34e-08 | 4.52e-01 | 0.0171 |
26071 | RTL8A | HTA11_7469_2000001011 | Human | Colorectum | AD | 1.16e-02 | 3.57e-01 | -0.0124 |
26071 | RTL8A | HTA11_6818_2000001021 | Human | Colorectum | AD | 1.67e-05 | 2.37e-01 | 0.0588 |
26071 | RTL8A | LZE2T | Human | Esophagus | ESCC | 5.44e-10 | 1.07e+00 | 0.082 |
26071 | RTL8A | LZE3D | Human | Esophagus | HGIN | 6.21e-05 | 1.20e+00 | 0.0668 |
26071 | RTL8A | LZE4T | Human | Esophagus | ESCC | 6.46e-40 | 1.06e+00 | 0.0811 |
26071 | RTL8A | LZE5T | Human | Esophagus | ESCC | 4.24e-14 | 6.74e-01 | 0.0514 |
26071 | RTL8A | LZE7T | Human | Esophagus | ESCC | 2.21e-38 | 2.01e+00 | 0.0667 |
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∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
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Malignant transformation related pathway analysis |
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Tissue | Disease Stage | Enriched GO biological Processes |
Oral cavity | OSCC | ![]() |
Oral cavity | LP | ![]() |
Oral cavity | EOLP | ![]() |
Oral cavity | NEOLP | ![]() |
Esophagus | HGIN | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
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GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
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Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
Page: 1 |
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Cell-cell communication analysis |
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Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
Page: 1 |
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Single-cell gene regulatory network inference analysis |
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TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
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Somatic mutation of malignant transformation related genes |
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Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
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Related drugs of malignant transformation related genes |
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(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
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