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Gene: RAMMET |
Gene summary for RAMMET |
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Gene information | Species | Human | Gene symbol | RAMMET | Gene ID | 83640 |
Gene name | RNA guanine-7 methyltransferase activating subunit | |
Gene Alias | C15orf18 | |
Cytomap | 15q25.2 | |
Gene Type | protein-coding | GO ID | GO:0001510 | UniProtAcc | Q9BTL3 |
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Malignant transformation analysis |
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Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
83640 | RAMMET | S014 | Human | Liver | HCC | 1.19e-50 | 1.36e+00 | 0.2254 |
83640 | RAMMET | S015 | Human | Liver | HCC | 1.35e-46 | 1.48e+00 | 0.2375 |
83640 | RAMMET | S016 | Human | Liver | HCC | 6.68e-56 | 1.35e+00 | 0.2243 |
83640 | RAMMET | S027 | Human | Liver | HCC | 2.89e-15 | 7.63e-01 | 0.2446 |
83640 | RAMMET | S028 | Human | Liver | HCC | 1.74e-31 | 9.71e-01 | 0.2503 |
83640 | RAMMET | S029 | Human | Liver | HCC | 4.74e-36 | 1.12e+00 | 0.2581 |
83640 | RAMMET | PTC01 | Human | Thyroid | PTC | 7.43e-16 | 3.30e-01 | 0.1899 |
83640 | RAMMET | PTC03 | Human | Thyroid | PTC | 6.13e-09 | 3.12e-01 | 0.1784 |
83640 | RAMMET | PTC04 | Human | Thyroid | PTC | 2.80e-17 | 3.45e-01 | 0.1927 |
83640 | RAMMET | PTC05 | Human | Thyroid | PTC | 1.41e-27 | 7.18e-01 | 0.2065 |
83640 | RAMMET | PTC06 | Human | Thyroid | PTC | 2.88e-31 | 6.56e-01 | 0.2057 |
83640 | RAMMET | PTC07 | Human | Thyroid | PTC | 3.07e-41 | 6.07e-01 | 0.2044 |
83640 | RAMMET | ATC09 | Human | Thyroid | ATC | 4.53e-07 | 2.68e-01 | 0.2871 |
83640 | RAMMET | ATC12 | Human | Thyroid | ATC | 8.48e-15 | 3.11e-01 | 0.34 |
83640 | RAMMET | ATC13 | Human | Thyroid | ATC | 1.45e-16 | 3.21e-01 | 0.34 |
83640 | RAMMET | ATC1 | Human | Thyroid | ATC | 2.63e-07 | 2.96e-01 | 0.2878 |
83640 | RAMMET | ATC2 | Human | Thyroid | ATC | 3.34e-11 | 8.53e-01 | 0.34 |
83640 | RAMMET | ATC4 | Human | Thyroid | ATC | 5.40e-19 | 4.14e-01 | 0.34 |
83640 | RAMMET | ATC5 | Human | Thyroid | ATC | 1.23e-17 | 3.57e-01 | 0.34 |
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∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
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Malignant transformation related pathway analysis |
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Tissue | Disease Stage | Enriched GO biological Processes |
Oral cavity | OSCC | ![]() |
Oral cavity | LP | ![]() |
Oral cavity | EOLP | ![]() |
Oral cavity | NEOLP | ![]() |
Esophagus | HGIN | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
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GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
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Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
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Cell-cell communication analysis |
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Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
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Single-cell gene regulatory network inference analysis |
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TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
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Somatic mutation of malignant transformation related genes |
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Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
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Related drugs of malignant transformation related genes |
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(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
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