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Gene: OR2A1-AS1 |
Gene summary for OR2A1-AS1 |
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Gene information | Species | Human | Gene symbol | OR2A1-AS1 | Gene ID | 101928492 |
Gene name | OR2A1 antisense RNA 1 | |
Gene Alias | OR2A1-AS1 | |
Cytomap | 7q35 | |
Gene Type | ncRNA | GO ID | NA | UniProtAcc | NA |
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Malignant transformation analysis |
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Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
101928492 | OR2A1-AS1 | LZE4T | Human | Esophagus | ESCC | 1.46e-02 | 1.06e-01 | 0.0811 |
101928492 | OR2A1-AS1 | LZE20T | Human | Esophagus | ESCC | 1.13e-03 | 1.05e-01 | 0.0662 |
101928492 | OR2A1-AS1 | LZE24T | Human | Esophagus | ESCC | 4.13e-09 | 2.64e-01 | 0.0596 |
101928492 | OR2A1-AS1 | P1T-E | Human | Esophagus | ESCC | 1.18e-08 | 4.17e-01 | 0.0875 |
101928492 | OR2A1-AS1 | P4T-E | Human | Esophagus | ESCC | 7.56e-11 | 2.08e-01 | 0.1323 |
101928492 | OR2A1-AS1 | P5T-E | Human | Esophagus | ESCC | 7.52e-23 | 4.26e-01 | 0.1327 |
101928492 | OR2A1-AS1 | P8T-E | Human | Esophagus | ESCC | 2.03e-09 | 1.69e-01 | 0.0889 |
101928492 | OR2A1-AS1 | P9T-E | Human | Esophagus | ESCC | 2.91e-28 | 6.60e-01 | 0.1131 |
101928492 | OR2A1-AS1 | P10T-E | Human | Esophagus | ESCC | 9.44e-07 | 1.20e-01 | 0.116 |
101928492 | OR2A1-AS1 | P11T-E | Human | Esophagus | ESCC | 2.11e-10 | 2.22e-01 | 0.1426 |
101928492 | OR2A1-AS1 | P12T-E | Human | Esophagus | ESCC | 1.53e-19 | 4.46e-01 | 0.1122 |
101928492 | OR2A1-AS1 | P15T-E | Human | Esophagus | ESCC | 3.87e-13 | 3.16e-01 | 0.1149 |
101928492 | OR2A1-AS1 | P16T-E | Human | Esophagus | ESCC | 3.50e-02 | 4.40e-02 | 0.1153 |
101928492 | OR2A1-AS1 | P17T-E | Human | Esophagus | ESCC | 3.05e-03 | 1.26e-01 | 0.1278 |
101928492 | OR2A1-AS1 | P20T-E | Human | Esophagus | ESCC | 4.27e-10 | 1.38e-01 | 0.1124 |
101928492 | OR2A1-AS1 | P21T-E | Human | Esophagus | ESCC | 1.96e-05 | 1.88e-01 | 0.1617 |
101928492 | OR2A1-AS1 | P22T-E | Human | Esophagus | ESCC | 8.59e-12 | 2.50e-01 | 0.1236 |
101928492 | OR2A1-AS1 | P23T-E | Human | Esophagus | ESCC | 1.42e-18 | 5.17e-01 | 0.108 |
101928492 | OR2A1-AS1 | P24T-E | Human | Esophagus | ESCC | 4.30e-10 | 2.58e-01 | 0.1287 |
101928492 | OR2A1-AS1 | P26T-E | Human | Esophagus | ESCC | 1.97e-10 | 2.47e-01 | 0.1276 |
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Tissue | Expression Dynamics | Abbreviation |
Esophagus | ![]() | ESCC: Esophageal squamous cell carcinoma |
HGIN: High-grade intraepithelial neoplasias | ||
LGIN: Low-grade intraepithelial neoplasias |
∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
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Malignant transformation related pathway analysis |
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Tissue | Disease Stage | Enriched GO biological Processes |
Oral cavity | OSCC | ![]() |
Oral cavity | LP | ![]() |
Oral cavity | EOLP | ![]() |
Oral cavity | NEOLP | ![]() |
Esophagus | HGIN | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
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GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
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Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
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Cell-cell communication analysis |
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Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
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Single-cell gene regulatory network inference analysis |
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TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
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Somatic mutation of malignant transformation related genes |
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Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
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Related drugs of malignant transformation related genes |
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(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
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