GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
GO:0007162 | Colorectum | SER | negative regulation of cell adhesion | 68/2897 | 303/18723 | 8.02e-04 | 1.01e-02 | 68 |
GO:0022408 | Colorectum | SER | negative regulation of cell-cell adhesion | 44/2897 | 196/18723 | 6.08e-03 | 4.42e-02 | 44 |
GO:004211016 | Oral cavity | OSCC | T cell activation | 245/7305 | 487/18723 | 2.00e-07 | 3.22e-06 | 245 |
GO:002240718 | Oral cavity | OSCC | regulation of cell-cell adhesion | 218/7305 | 448/18723 | 1.71e-05 | 1.68e-04 | 218 |
GO:005086315 | Oral cavity | OSCC | regulation of T cell activation | 161/7305 | 329/18723 | 1.44e-04 | 1.02e-03 | 161 |
GO:000715916 | Oral cavity | OSCC | leukocyte cell-cell adhesion | 178/7305 | 371/18723 | 2.44e-04 | 1.57e-03 | 178 |
GO:190303715 | Oral cavity | OSCC | regulation of leukocyte cell-cell adhesion | 162/7305 | 336/18723 | 3.39e-04 | 2.08e-03 | 162 |
GO:000268310 | Oral cavity | OSCC | negative regulation of immune system process | 204/7305 | 434/18723 | 3.72e-04 | 2.27e-03 | 204 |
GO:004209816 | Oral cavity | OSCC | T cell proliferation | 100/7305 | 199/18723 | 7.93e-04 | 4.27e-03 | 100 |
GO:00071629 | Oral cavity | OSCC | negative regulation of cell adhesion | 145/7305 | 303/18723 | 9.95e-04 | 5.18e-03 | 145 |
GO:00466333 | Oral cavity | OSCC | alpha-beta T cell proliferation | 24/7305 | 38/18723 | 2.21e-03 | 1.00e-02 | 24 |
GO:00466403 | Oral cavity | OSCC | regulation of alpha-beta T cell proliferation | 22/7305 | 35/18723 | 3.65e-03 | 1.51e-02 | 22 |
GO:0046642 | Oral cavity | OSCC | negative regulation of alpha-beta T cell proliferation | 10/7305 | 13/18723 | 6.32e-03 | 2.35e-02 | 10 |
GO:00706618 | Oral cavity | OSCC | leukocyte proliferation | 145/7305 | 318/18723 | 9.31e-03 | 3.33e-02 | 145 |
GO:0035739 | Oral cavity | OSCC | CD4-positive, alpha-beta T cell proliferation | 9/7305 | 12/18723 | 1.27e-02 | 4.24e-02 | 9 |
GO:2000561 | Oral cavity | OSCC | regulation of CD4-positive, alpha-beta T cell proliferation | 9/7305 | 12/18723 | 1.27e-02 | 4.24e-02 | 9 |
GO:00224086 | Oral cavity | OSCC | negative regulation of cell-cell adhesion | 92/7305 | 196/18723 | 1.41e-02 | 4.64e-02 | 92 |
GO:00466517 | Oral cavity | OSCC | lymphocyte proliferation | 131/7305 | 288/18723 | 1.41e-02 | 4.67e-02 | 131 |
Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
LGALS9B | SNV | Missense_Mutation | | c.584N>T | p.Thr195Ile | p.T195I | Q3B8N2 | protein_coding | deleterious(0.01) | benign(0.187) | TCGA-A8-A079-01 | Breast | breast invasive carcinoma | Female | >=65 | III/IV | Chemotherapy | 5-fluorouracil | SD |
LGALS9B | SNV | Missense_Mutation | novel | c.554N>A | p.Arg185Gln | p.R185Q | Q3B8N2 | protein_coding | tolerated(0.42) | benign(0.001) | TCGA-B6-A1KF-01 | Breast | breast invasive carcinoma | Female | >=65 | I/II | Unknown | Unknown | SD |
LGALS9B | insertion | Nonsense_Mutation | novel | c.148_149insCCAGCCCTATCAGGT | p.Gln50delinsProSerProIleArgTer | p.Q50delinsPSPIR* | Q3B8N2 | protein_coding | | | TCGA-A8-A08S-01 | Breast | breast invasive carcinoma | Female | >=65 | I/II | Hormone Therapy | anastrozole | SD |
LGALS9B | SNV | Missense_Mutation | rs768504475 | c.530N>A | p.Arg177His | p.R177H | Q3B8N2 | protein_coding | tolerated(0.26) | benign(0.006) | TCGA-AA-3492-01 | Colorectum | colon adenocarcinoma | Female | >=65 | I/II | Unknown | Unknown | SD |
LGALS9B | SNV | Missense_Mutation | | c.234G>T | p.Gln78His | p.Q78H | Q3B8N2 | protein_coding | deleterious(0.03) | benign(0.062) | TCGA-AA-A010-01 | Colorectum | colon adenocarcinoma | Female | <65 | I/II | Chemotherapy | folinic | CR |
LGALS9B | SNV | Missense_Mutation | rs752504822 | c.607N>A | p.Ala203Thr | p.A203T | Q3B8N2 | protein_coding | tolerated(0.54) | benign(0) | TCGA-WS-AB45-01 | Colorectum | colon adenocarcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
LGALS9B | SNV | Missense_Mutation | rs200824290 | c.976N>A | p.Val326Met | p.V326M | Q3B8N2 | protein_coding | tolerated(0.18) | benign(0.017) | TCGA-A5-A0G1-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | >=65 | I/II | Unknown | Unknown | SD |
LGALS9B | SNV | Missense_Mutation | novel | c.676N>T | p.Pro226Ser | p.P226S | Q3B8N2 | protein_coding | deleterious(0) | probably_damaging(1) | TCGA-A5-A0G2-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | III/IV | Unknown | Unknown | SD |
LGALS9B | SNV | Missense_Mutation | novel | c.707A>G | p.Tyr236Cys | p.Y236C | Q3B8N2 | protein_coding | tolerated(0.09) | benign(0.226) | TCGA-B5-A3FA-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | >=65 | I/II | Unknown | Unknown | SD |
LGALS9B | SNV | Missense_Mutation | rs768202333 | c.994C>T | p.Arg332Cys | p.R332C | Q3B8N2 | protein_coding | deleterious(0.02) | probably_damaging(0.922) | TCGA-B5-A3FC-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |