GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
GO:000165511 | Lung | AIS | urogenital system development | 63/1849 | 338/18723 | 5.46e-07 | 4.08e-05 | 63 |
GO:000182211 | Lung | AIS | kidney development | 53/1849 | 293/18723 | 1.04e-05 | 4.25e-04 | 53 |
GO:007200111 | Lung | AIS | renal system development | 54/1849 | 302/18723 | 1.21e-05 | 4.71e-04 | 54 |
GO:007099713 | Lung | AIS | neuron death | 58/1849 | 361/18723 | 1.39e-04 | 3.05e-03 | 58 |
GO:007207311 | Lung | AIS | kidney epithelium development | 27/1849 | 136/18723 | 3.21e-04 | 5.83e-03 | 27 |
GO:190121413 | Lung | AIS | regulation of neuron death | 50/1849 | 319/18723 | 6.90e-04 | 1.02e-02 | 50 |
GO:0018212 | Lung | AIS | peptidyl-tyrosine modification | 56/1849 | 378/18723 | 1.35e-03 | 1.68e-02 | 56 |
GO:0018108 | Lung | AIS | peptidyl-tyrosine phosphorylation | 55/1849 | 375/18723 | 1.87e-03 | 2.08e-02 | 55 |
GO:00720013 | Lung | MIAC | renal system development | 32/967 | 302/18723 | 9.64e-05 | 4.19e-03 | 32 |
GO:000182221 | Lung | MIAC | kidney development | 31/967 | 293/18723 | 1.27e-04 | 5.13e-03 | 31 |
GO:000165521 | Lung | MIAC | urogenital system development | 34/967 | 338/18723 | 1.63e-04 | 6.25e-03 | 34 |
GO:007207321 | Lung | MIAC | kidney epithelium development | 17/967 | 136/18723 | 6.48e-04 | 1.56e-02 | 17 |
GO:007099723 | Lung | MIAC | neuron death | 31/967 | 361/18723 | 3.97e-03 | 4.79e-02 | 31 |
GO:0070997113 | Thyroid | PTC | neuron death | 171/5968 | 361/18723 | 4.32e-10 | 1.38e-08 | 171 |
GO:1901214113 | Thyroid | PTC | regulation of neuron death | 151/5968 | 319/18723 | 4.74e-09 | 1.24e-07 | 151 |
GO:0051402112 | Thyroid | PTC | neuron apoptotic process | 118/5968 | 246/18723 | 8.99e-08 | 1.81e-06 | 118 |
GO:0043523110 | Thyroid | PTC | regulation of neuron apoptotic process | 102/5968 | 212/18723 | 5.45e-07 | 8.76e-06 | 102 |
GO:000182215 | Thyroid | PTC | kidney development | 133/5968 | 293/18723 | 7.57e-07 | 1.18e-05 | 133 |
GO:000165517 | Thyroid | PTC | urogenital system development | 149/5968 | 338/18723 | 1.41e-06 | 2.01e-05 | 149 |
GO:007200114 | Thyroid | PTC | renal system development | 135/5968 | 302/18723 | 1.76e-06 | 2.43e-05 | 135 |
Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
CRLF1 | SNV | Missense_Mutation | novel | c.995A>C | p.His332Pro | p.H332P | O75462 | protein_coding | deleterious(0.01) | possibly_damaging(0.543) | TCGA-AR-A1AY-01 | Breast | breast invasive carcinoma | Female | >=65 | I/II | Unspecific | Doxorubicin | SD |
CRLF1 | SNV | Missense_Mutation | | c.1121N>A | p.Leu374His | p.L374H | O75462 | protein_coding | deleterious_low_confidence(0) | possibly_damaging(0.533) | TCGA-GM-A2DN-01 | Breast | breast invasive carcinoma | Female | <65 | I/II | Chemotherapy | taxol | CR |
CRLF1 | SNV | Missense_Mutation | novel | c.805C>G | p.Gln269Glu | p.Q269E | O75462 | protein_coding | tolerated(0.14) | possibly_damaging(0.608) | TCGA-LL-A73Y-01 | Breast | breast invasive carcinoma | Female | >=65 | I/II | Chemotherapy | taxotere | SD |
CRLF1 | deletion | Frame_Shift_Del | novel | c.420delN | p.Asn140LysfsTer9 | p.N140Kfs*9 | O75462 | protein_coding | | | TCGA-D8-A27V-01 | Breast | breast invasive carcinoma | Female | <65 | I/II | Hormone Therapy | tamoxiphen | SD |
CRLF1 | SNV | Missense_Mutation | novel | c.805C>G | p.Gln269Glu | p.Q269E | O75462 | protein_coding | tolerated(0.14) | possibly_damaging(0.608) | TCGA-MY-A5BF-01 | Cervix | cervical & endocervical cancer | Female | >=65 | I/II | Chemotherapy | cisplatin | CR |
CRLF1 | SNV | Missense_Mutation | rs745875637 | c.1061N>A | p.Arg354Gln | p.R354Q | O75462 | protein_coding | tolerated_low_confidence(0.1) | benign(0.006) | TCGA-UC-A7PF-01 | Cervix | cervical & endocervical cancer | Female | <65 | I/II | Unknown | Unknown | SD |
CRLF1 | SNV | Missense_Mutation | | c.1237N>G | p.Arg413Gly | p.R413G | O75462 | protein_coding | deleterious_low_confidence(0) | possibly_damaging(0.879) | TCGA-AA-3530-01 | Colorectum | colon adenocarcinoma | Male | >=65 | I/II | Unknown | Unknown | SD |
CRLF1 | SNV | Missense_Mutation | rs780528096 | c.214N>A | p.Glu72Lys | p.E72K | O75462 | protein_coding | tolerated(0.15) | benign(0.026) | TCGA-CA-6718-01 | Colorectum | colon adenocarcinoma | Male | <65 | I/II | Unknown | Unknown | PD |
CRLF1 | insertion | Frame_Shift_Ins | novel | c.254dupC | p.Glu86Ter | p.E86* | O75462 | protein_coding | | | TCGA-AA-3947-01 | Colorectum | colon adenocarcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
CRLF1 | SNV | Missense_Mutation | novel | c.682G>A | p.Asp228Asn | p.D228N | O75462 | protein_coding | deleterious(0) | possibly_damaging(0.558) | TCGA-A5-A0G2-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | III/IV | Unknown | Unknown | SD |