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Gene: CYTOR |
Gene summary for CYTOR |
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Gene information | Species | Human | Gene symbol | CYTOR | Gene ID | 112597 |
Gene name | cytoskeleton regulator RNA | |
Gene Alias | C2orf59 | |
Cytomap | 2p11.2 | |
Gene Type | ncRNA | GO ID | NA | UniProtAcc | NA |
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Malignant transformation analysis |
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Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
112597 | CYTOR | GSM4909281 | Human | Breast | IDC | 3.07e-08 | 2.22e-01 | 0.21 |
112597 | CYTOR | GSM4909282 | Human | Breast | IDC | 6.33e-08 | 1.80e-01 | -0.0288 |
112597 | CYTOR | GSM4909286 | Human | Breast | IDC | 8.50e-07 | -3.52e-01 | 0.1081 |
112597 | CYTOR | GSM4909291 | Human | Breast | IDC | 2.55e-10 | 5.15e-01 | 0.1753 |
112597 | CYTOR | GSM4909298 | Human | Breast | IDC | 1.70e-07 | -1.96e-02 | 0.1551 |
112597 | CYTOR | GSM4909299 | Human | Breast | IDC | 5.14e-15 | 3.25e-01 | 0.035 |
112597 | CYTOR | GSM4909300 | Human | Breast | IDC | 4.35e-07 | 4.46e-01 | 0.0334 |
112597 | CYTOR | GSM4909305 | Human | Breast | IDC | 9.58e-04 | 1.10e-01 | 0.0436 |
112597 | CYTOR | GSM4909306 | Human | Breast | IDC | 1.69e-03 | 6.55e-02 | 0.1564 |
112597 | CYTOR | GSM4909307 | Human | Breast | IDC | 5.54e-04 | 1.83e-01 | 0.1569 |
112597 | CYTOR | GSM4909308 | Human | Breast | IDC | 2.27e-13 | 1.96e-01 | 0.158 |
112597 | CYTOR | GSM4909309 | Human | Breast | IDC | 1.84e-08 | 5.14e-01 | 0.0483 |
112597 | CYTOR | GSM4909313 | Human | Breast | IDC | 3.52e-06 | 5.06e-01 | 0.0391 |
112597 | CYTOR | GSM4909317 | Human | Breast | IDC | 2.72e-05 | 1.87e-01 | 0.1355 |
112597 | CYTOR | GSM4909319 | Human | Breast | IDC | 2.22e-06 | -2.49e-01 | 0.1563 |
112597 | CYTOR | ctrl6 | Human | Breast | Precancer | 1.93e-14 | 7.28e-01 | -0.0061 |
112597 | CYTOR | brca1 | Human | Breast | Precancer | 3.69e-10 | -3.70e-01 | -0.0338 |
112597 | CYTOR | brca2 | Human | Breast | Precancer | 3.69e-10 | -3.70e-01 | -0.024 |
112597 | CYTOR | brca3 | Human | Breast | Precancer | 3.52e-11 | -3.70e-01 | -0.0263 |
112597 | CYTOR | brca10 | Human | Breast | Precancer | 5.30e-15 | 5.14e-01 | -0.0029 |
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∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
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Malignant transformation related pathway analysis |
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Tissue | Disease Stage | Enriched GO biological Processes |
Cervix | N_HPV | ![]() |
Endometrium | AEH | ![]() |
Endometrium | EEC | ![]() |
Prostate | BPH | ![]() |
Prostate | Tumor | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
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GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
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Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
Page: 1 |
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Cell-cell communication analysis |
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Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
Page: 1 |
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Single-cell gene regulatory network inference analysis |
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TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
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Somatic mutation of malignant transformation related genes |
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Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
Page: 1 |
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Related drugs of malignant transformation related genes |
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(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
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