GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
GO:0070482 | Colorectum | AD | response to oxygen levels | 99/3918 | 347/18723 | 4.29e-04 | 4.82e-03 | 99 |
GO:0003158 | Colorectum | AD | endothelium development | 44/3918 | 136/18723 | 1.20e-03 | 1.07e-02 | 44 |
GO:0045446 | Colorectum | AD | endothelial cell differentiation | 39/3918 | 118/18723 | 1.42e-03 | 1.22e-02 | 39 |
GO:0010876 | Colorectum | AD | lipid localization | 120/3918 | 448/18723 | 1.59e-03 | 1.33e-02 | 120 |
GO:0006869 | Colorectum | AD | lipid transport | 108/3918 | 398/18723 | 1.67e-03 | 1.39e-02 | 108 |
GO:0001666 | Colorectum | AD | response to hypoxia | 86/3918 | 307/18723 | 1.77e-03 | 1.46e-02 | 86 |
GO:0036293 | Colorectum | AD | response to decreased oxygen levels | 88/3918 | 322/18723 | 3.42e-03 | 2.49e-02 | 88 |
GO:00704821 | Colorectum | SER | response to oxygen levels | 79/2897 | 347/18723 | 1.99e-04 | 3.64e-03 | 79 |
GO:00016661 | Colorectum | SER | response to hypoxia | 69/2897 | 307/18723 | 7.07e-04 | 9.39e-03 | 69 |
GO:00362931 | Colorectum | SER | response to decreased oxygen levels | 71/2897 | 322/18723 | 1.04e-03 | 1.22e-02 | 71 |
GO:00704822 | Colorectum | MSS | response to oxygen levels | 85/3467 | 347/18723 | 3.08e-03 | 2.34e-02 | 85 |
GO:00031581 | Colorectum | MSS | endothelium development | 38/3467 | 136/18723 | 4.53e-03 | 3.19e-02 | 38 |
GO:00016662 | Colorectum | MSS | response to hypoxia | 75/3467 | 307/18723 | 5.56e-03 | 3.78e-02 | 75 |
GO:00108761 | Colorectum | MSS | lipid localization | 104/3467 | 448/18723 | 6.76e-03 | 4.38e-02 | 104 |
GO:00454461 | Colorectum | MSS | endothelial cell differentiation | 33/3467 | 118/18723 | 7.66e-03 | 4.81e-02 | 33 |
GO:00704823 | Colorectum | FAP | response to oxygen levels | 77/2622 | 347/18723 | 2.08e-05 | 5.05e-04 | 77 |
GO:00016663 | Colorectum | FAP | response to hypoxia | 68/2622 | 307/18723 | 6.53e-05 | 1.25e-03 | 68 |
GO:00362932 | Colorectum | FAP | response to decreased oxygen levels | 70/2622 | 322/18723 | 9.49e-05 | 1.61e-03 | 70 |
GO:00068691 | Colorectum | FAP | lipid transport | 81/2622 | 398/18723 | 2.84e-04 | 3.76e-03 | 81 |
GO:0030856 | Colorectum | FAP | regulation of epithelial cell differentiation | 36/2622 | 154/18723 | 1.16e-03 | 1.11e-02 | 36 |
Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
APOLD1 | SNV | Missense_Mutation | novel | c.619N>G | p.Arg207Gly | p.R207G | Q96LR9 | protein_coding | deleterious(0) | benign(0.206) | TCGA-A8-A07J-01 | Breast | breast invasive carcinoma | Female | <65 | I/II | Chemotherapy | 5-fluorouracil | CR |
APOLD1 | SNV | Missense_Mutation | | c.703N>A | p.Glu235Lys | p.E235K | Q96LR9 | protein_coding | tolerated(0.06) | benign(0.079) | TCGA-D8-A13Y-01 | Breast | breast invasive carcinoma | Female | <65 | I/II | Chemotherapy | doxorubicin | SD |
APOLD1 | insertion | Frame_Shift_Ins | novel | c.609_610insCATCTGGTCTGGTCTGCAGCAAGTCCACAGAAGCTACA | p.Phe204HisfsTer36 | p.F204Hfs*36 | Q96LR9 | protein_coding | | | TCGA-A2-A0EQ-01 | Breast | breast invasive carcinoma | Female | <65 | I/II | Chemotherapy | adriamycin | SD |
APOLD1 | insertion | Frame_Shift_Ins | novel | c.617_618insGGCCAGGTGCTGCGCCTGCGCG | p.Arg207AlafsTer23 | p.R207Afs*23 | Q96LR9 | protein_coding | | | TCGA-A8-A07J-01 | Breast | breast invasive carcinoma | Female | <65 | I/II | Chemotherapy | 5-fluorouracil | CR |
APOLD1 | SNV | Missense_Mutation | | c.509N>G | p.Glu170Gly | p.E170G | Q96LR9 | protein_coding | deleterious(0.01) | benign(0.061) | TCGA-A6-6780-01 | Colorectum | colon adenocarcinoma | Male | >=65 | I/II | Unknown | Unknown | SD |
APOLD1 | SNV | Missense_Mutation | novel | c.520N>T | p.Arg174Cys | p.R174C | Q96LR9 | protein_coding | deleterious(0.02) | possibly_damaging(0.841) | TCGA-AA-3968-01 | Colorectum | colon adenocarcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
APOLD1 | SNV | Missense_Mutation | | c.609N>A | p.Phe203Leu | p.F203L | Q96LR9 | protein_coding | tolerated(0.14) | benign(0.089) | TCGA-AA-A010-01 | Colorectum | colon adenocarcinoma | Female | <65 | I/II | Chemotherapy | folinic | CR |
APOLD1 | SNV | Missense_Mutation | | c.516N>A | p.Phe172Leu | p.F172L | Q96LR9 | protein_coding | tolerated(0.76) | benign(0.098) | TCGA-AP-A059-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | >=65 | I/II | Unknown | Unknown | SD |
APOLD1 | SNV | Missense_Mutation | | c.671N>T | p.Ala224Val | p.A224V | Q96LR9 | protein_coding | tolerated(0.09) | benign(0.055) | TCGA-BG-A0W1-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | >=65 | I/II | Unknown | Unknown | SD |
APOLD1 | SNV | Missense_Mutation | | c.609C>A | p.Phe203Leu | p.F203L | Q96LR9 | protein_coding | tolerated(0.14) | benign(0.089) | TCGA-BS-A0UV-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | III/IV | Unknown | Unknown | SD |