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Gene: JPT2 |
Gene summary for JPT2 |
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Gene information | Species | Human | Gene symbol | JPT2 | Gene ID | 90861 |
Gene name | Jupiter microtubule associated homolog 2 | |
Gene Alias | C16orf34 | |
Cytomap | 16p13.3 | |
Gene Type | protein-coding | GO ID | GO:0005575 | UniProtAcc | Q9H910 |
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Malignant transformation analysis |
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Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
90861 | JPT2 | LZE2T | Human | Esophagus | ESCC | 1.52e-08 | 6.95e-01 | 0.082 |
90861 | JPT2 | LZE4T | Human | Esophagus | ESCC | 5.87e-26 | 5.85e-01 | 0.0811 |
90861 | JPT2 | LZE5T | Human | Esophagus | ESCC | 1.00e-09 | 5.15e-01 | 0.0514 |
90861 | JPT2 | LZE7T | Human | Esophagus | ESCC | 5.23e-19 | 7.37e-01 | 0.0667 |
90861 | JPT2 | LZE8T | Human | Esophagus | ESCC | 5.01e-31 | 7.82e-01 | 0.067 |
90861 | JPT2 | LZE20T | Human | Esophagus | ESCC | 1.30e-10 | 4.27e-01 | 0.0662 |
90861 | JPT2 | LZE22D1 | Human | Esophagus | HGIN | 8.03e-04 | 1.82e-01 | 0.0595 |
90861 | JPT2 | LZE22T | Human | Esophagus | ESCC | 3.15e-15 | 8.56e-01 | 0.068 |
90861 | JPT2 | LZE24T | Human | Esophagus | ESCC | 1.53e-37 | 9.27e-01 | 0.0596 |
90861 | JPT2 | LZE21T | Human | Esophagus | ESCC | 2.35e-12 | 5.28e-01 | 0.0655 |
90861 | JPT2 | LZE6T | Human | Esophagus | ESCC | 3.41e-18 | 5.79e-01 | 0.0845 |
90861 | JPT2 | S014 | Human | Liver | HCC | 1.70e-32 | 9.56e-01 | 0.2254 |
90861 | JPT2 | S015 | Human | Liver | HCC | 2.07e-32 | 1.04e+00 | 0.2375 |
90861 | JPT2 | S016 | Human | Liver | HCC | 1.94e-36 | 8.91e-01 | 0.2243 |
90861 | JPT2 | S027 | Human | Liver | HCC | 3.33e-21 | 1.17e+00 | 0.2446 |
90861 | JPT2 | S028 | Human | Liver | HCC | 7.15e-47 | 1.49e+00 | 0.2503 |
90861 | JPT2 | S029 | Human | Liver | HCC | 2.38e-37 | 1.45e+00 | 0.2581 |
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∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
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Malignant transformation related pathway analysis |
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Tissue | Disease Stage | Enriched GO biological Processes |
Breast | Precancer | ![]() |
Breast | IDC | ![]() |
Breast | DCIS | ![]() |
Cervix | CC | ![]() |
Cervix | HSIL_HPV | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
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GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
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Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
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Cell-cell communication analysis |
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Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
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Single-cell gene regulatory network inference analysis |
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TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
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Somatic mutation of malignant transformation related genes |
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Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
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Related drugs of malignant transformation related genes |
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(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
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