![]() |
|||||
|
![]() | |
![]() | |
![]() | |
![]() | |
![]() | |
![]() | |
![]() |
Gene: BNIP5 |
Gene summary for BNIP5 |
![]() |
Gene information | Species | Human | Gene symbol | BNIP5 | Gene ID | 389384 |
Gene name | BCL2 interacting protein 5 | |
Gene Alias | C6orf222 | |
Cytomap | 6p21.31 | |
Gene Type | protein-coding | GO ID | GO:0003674 | UniProtAcc | P0C671 |
Top |
Malignant transformation analysis |
![]() |
![]() |
Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
389384 | BNIP5 | HTA11_411_2000001011 | Human | Colorectum | SER | 4.01e-04 | 6.61e-01 | -0.2602 |
389384 | BNIP5 | HTA11_2112_2000001011 | Human | Colorectum | SER | 1.90e-02 | 2.44e-01 | -0.2196 |
389384 | BNIP5 | HTA11_696_2000001011 | Human | Colorectum | AD | 3.61e-02 | 8.15e-02 | -0.1464 |
389384 | BNIP5 | HTA11_866_2000001011 | Human | Colorectum | AD | 8.13e-03 | 1.02e-01 | -0.1001 |
389384 | BNIP5 | HTA11_1391_2000001011 | Human | Colorectum | AD | 5.08e-04 | 1.43e-01 | -0.059 |
389384 | BNIP5 | HTA11_866_3004761011 | Human | Colorectum | AD | 3.98e-03 | 1.42e-01 | 0.096 |
389384 | BNIP5 | HTA11_7696_3000711011 | Human | Colorectum | AD | 3.85e-03 | 9.90e-02 | 0.0674 |
389384 | BNIP5 | Pat01-B | Human | Stomach | GC | 3.95e-53 | 8.88e-01 | 0.5754 |
389384 | BNIP5 | Pat02-B | Human | Stomach | GC | 7.57e-28 | 4.71e-01 | 0.0368 |
389384 | BNIP5 | Pat03-B | Human | Stomach | GC | 1.13e-32 | 6.38e-01 | 0.3693 |
389384 | BNIP5 | Pat04-B | Human | Stomach | GC | 1.45e-22 | 6.33e-01 | -0.1483 |
389384 | BNIP5 | Pat05-B | Human | Stomach | GC | 3.56e-13 | 4.70e-01 | -0.0353 |
389384 | BNIP5 | Pat06-B | Human | Stomach | GC | 7.72e-19 | 3.72e-01 | -0.1961 |
389384 | BNIP5 | Pat07-B | Human | Stomach | GC | 3.71e-21 | 8.46e-01 | 0.0935 |
389384 | BNIP5 | Pat08-B | Human | Stomach | GC | 5.51e-06 | 3.66e-01 | 0.0182 |
389384 | BNIP5 | Pat10-B | Human | Stomach | GC | 1.84e-10 | 5.29e-01 | 0.084 |
389384 | BNIP5 | Pat11-B | Human | Stomach | GC | 2.61e-28 | 7.71e-01 | -0.182 |
389384 | BNIP5 | Pat12-B | Human | Stomach | GC | 2.87e-12 | 3.14e-01 | 0.0325 |
389384 | BNIP5 | Pat15-B | Human | Stomach | GC | 5.70e-17 | 4.54e-01 | -0.0778 |
389384 | BNIP5 | Pat16-B | Human | Stomach | GC | 1.40e-19 | 5.26e-01 | 0.1918 |
Page: 1 2 |
![]() |
∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
Top |
Malignant transformation related pathway analysis |
![]() |
![]() |
Tissue | Disease Stage | Enriched GO biological Processes |
Breast | Precancer | ![]() |
Breast | IDC | ![]() |
Breast | DCIS | ![]() |
Cervix | CC | ![]() |
Cervix | HSIL_HPV | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
Page: 1 2 3 4 5 6 7 8 9 |
![]() |
GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
Page: 1 |
![]() |
Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
Page: 1 |
Top |
Cell-cell communication analysis |
![]() |
Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
Page: 1 |
Top |
Single-cell gene regulatory network inference analysis |
![]() |
TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
Page: 1 |
Top |
Somatic mutation of malignant transformation related genes |
![]() |
Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
Page: 1 |
Top |
Related drugs of malignant transformation related genes |
![]() |
(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
Page: 1 |