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Gene: AGPAT9 |
Gene summary for AGPAT9 |
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Gene information | Species | Human | Gene symbol | AGPAT9 | Gene ID | 84803 |
Gene name | glycerol-3-phosphate acyltransferase 3 | |
Gene Alias | AGPAT 10 | |
Cytomap | 4q21.23 | |
Gene Type | protein-coding | GO ID | GO:0006072 | UniProtAcc | A0A024RDG5 |
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Malignant transformation analysis |
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Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
84803 | AGPAT9 | NAG_1 | Human | Stomach | CSG | 3.31e-20 | 6.45e-01 | -0.3534 |
84803 | AGPAT9 | NAG_2 | Human | Stomach | CSG | 1.74e-15 | 5.61e-01 | -0.3324 |
84803 | AGPAT9 | CAG_3 | Human | Stomach | CAG | 6.84e-09 | 2.53e-01 | -0.2766 |
84803 | AGPAT9 | SIM_1 | Human | Stomach | SIM | 1.78e-03 | 1.99e-01 | 0.3573 |
84803 | AGPAT9 | SIM_4 | Human | Stomach | SIM | 4.76e-10 | 4.22e-01 | 0.2664 |
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∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
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Malignant transformation related pathway analysis |
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Tissue | Disease Stage | Enriched GO biological Processes |
Breast | Precancer | ![]() |
Breast | IDC | ![]() |
Breast | DCIS | ![]() |
Cervix | CC | ![]() |
Cervix | HSIL_HPV | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
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GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
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Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
hsa005615 | Liver | HCC | Glycerolipid metabolism | 41/4020 | 63/8465 | 3.59e-03 | 1.12e-02 | 6.22e-03 | 41 |
hsa0056112 | Liver | HCC | Glycerolipid metabolism | 41/4020 | 63/8465 | 3.59e-03 | 1.12e-02 | 6.22e-03 | 41 |
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Cell-cell communication analysis |
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Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
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Single-cell gene regulatory network inference analysis |
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TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
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Somatic mutation of malignant transformation related genes |
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Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
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Related drugs of malignant transformation related genes |
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(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
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