TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
ZNF197 | CD4TN | Breast | ADJ | NLN,SLC27A3,CENPB, etc. | 3.25e-02 | ![The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression.](images/gene_regulatory/Breast/Str/TF_ADJ/regulons_activity_in_dotplot.png) |
ZNF197 | M2MAC | Breast | Healthy | NLN,SLC27A3,CENPB, etc. | 7.59e-03 | ![The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression.](images/gene_regulatory/Breast/Str/TF_Healthy/regulons_activity_in_dotplot.png) |
ZNF197 | TFH | Breast | Precancer | NLN,SLC27A3,CENPB, etc. | 2.24e-02 | ![The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression.](images/gene_regulatory/Breast/Str/TF_Precancer/regulons_activity_in_dotplot.png) |
ZNF197 | ECM | Lung | AAH | TAFA2,AGK,ATP1A1-AS1, etc. | 3.84e-01 | ![The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression.](images/gene_regulatory/Lung/Str/TF_AAH/regulons_activity_in_dotplot.png) |
ZNF197 | ECM | Lung | ADJ | TAFA2,AGK,ATP1A1-AS1, etc. | 3.51e-01 | ![The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression.](images/gene_regulatory/Lung/Str/TF_ADJ/regulons_activity_in_dotplot.png) |
ZNF197 | ECM | Lung | AIS | TAFA2,AGK,ATP1A1-AS1, etc. | 3.25e-01 | ![The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression.](images/gene_regulatory/Lung/Str/TF_AIS/regulons_activity_in_dotplot.png) |
ZNF197 | ECM | Lung | IAC | TAFA2,AGK,ATP1A1-AS1, etc. | 1.20e-01 | ![The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression.](images/gene_regulatory/Lung/Str/TF_IAC/regulons_activity_in_dotplot.png) |
ZNF197 | BN | Prostate | ADJ | TM9SF3,ATF7IP2,PKD2, etc. | 2.75e-02 | ![The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression.](images/gene_regulatory/Prostate/Str/TF_ADJ/regulons_activity_in_dotplot.png) |
ZNF197 | BN | Prostate | BPH | TM9SF3,ATF7IP2,PKD2, etc. | 2.00e-01 | ![The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression.](images/gene_regulatory/Prostate/Str/TF_BPH/regulons_activity_in_dotplot.png) |
ZNF197 | PLA | Prostate | BPH | TM9SF3,ATF7IP2,PKD2, etc. | 3.87e-02 | ![The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression.](images/gene_regulatory/Prostate/Str/TF_BPH/regulons_activity_in_dotplot.png) |
Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
ZNF197 | SNV | Missense_Mutation | | c.604N>G | p.Gln202Glu | p.Q202E | O14709 | protein_coding | tolerated(0.44) | possibly_damaging(0.759) | TCGA-AC-A23H-01 | Breast | breast invasive carcinoma | Female | >=65 | I/II | Unknown | Unknown | PD |
ZNF197 | SNV | Missense_Mutation | novel | c.554N>A | p.Ser185Tyr | p.S185Y | O14709 | protein_coding | tolerated(0.08) | benign(0.305) | TCGA-AN-A046-01 | Breast | breast invasive carcinoma | Female | >=65 | I/II | Unknown | Unknown | SD |
ZNF197 | SNV | Missense_Mutation | | c.2597N>T | p.Arg866Ile | p.R866I | O14709 | protein_coding | tolerated(0.05) | probably_damaging(0.995) | TCGA-AN-A046-01 | Breast | breast invasive carcinoma | Female | >=65 | I/II | Unknown | Unknown | SD |
ZNF197 | SNV | Missense_Mutation | | c.3075N>C | p.Glu1025Asp | p.E1025D | O14709 | protein_coding | tolerated_low_confidence(0.45) | benign(0.022) | TCGA-AN-A0XW-01 | Breast | breast invasive carcinoma | Female | <65 | III/IV | Unknown | Unknown | SD |
ZNF197 | SNV | Missense_Mutation | | c.1093N>A | p.Glu365Lys | p.E365K | O14709 | protein_coding | tolerated(0.71) | benign(0.034) | TCGA-B6-A0WZ-01 | Breast | breast invasive carcinoma | Female | <65 | I/II | Unknown | Unknown | PD |
ZNF197 | SNV | Missense_Mutation | rs375070406 | c.349N>A | p.Val117Ile | p.V117I | O14709 | protein_coding | tolerated(0.17) | benign(0.011) | TCGA-BH-A0B6-01 | Breast | breast invasive carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
ZNF197 | SNV | Missense_Mutation | novel | c.23A>G | p.His8Arg | p.H8R | O14709 | protein_coding | tolerated_low_confidence(0.31) | probably_damaging(0.921) | TCGA-2W-A8YY-01 | Cervix | cervical & endocervical cancer | Female | <65 | I/II | Chemotherapy | cisplatin | CR |
ZNF197 | SNV | Missense_Mutation | | c.2681G>T | p.Arg894Ile | p.R894I | O14709 | protein_coding | deleterious(0.02) | probably_damaging(0.999) | TCGA-2W-A8YY-01 | Cervix | cervical & endocervical cancer | Female | <65 | I/II | Chemotherapy | cisplatin | CR |
ZNF197 | SNV | Missense_Mutation | | c.845N>C | p.Gly282Ala | p.G282A | O14709 | protein_coding | tolerated(0.63) | benign(0.136) | TCGA-EK-A3GK-01 | Cervix | cervical & endocervical cancer | Female | <65 | I/II | Unknown | Unknown | SD |
ZNF197 | SNV | Missense_Mutation | | c.937N>A | p.Glu313Lys | p.E313K | O14709 | protein_coding | tolerated(0.62) | benign(0) | TCGA-EK-A3GK-01 | Cervix | cervical & endocervical cancer | Female | <65 | I/II | Unknown | Unknown | SD |