![]() |
|||||
|
![]() | |
![]() | |
![]() | |
![]() | |
![]() | |
![]() | |
![]() |
Gene: SGOL1 |
Gene summary for SGOL1 |
![]() |
Gene information | Species | Human | Gene symbol | SGOL1 | Gene ID | 151648 |
Gene name | shugoshin 1 | |
Gene Alias | CAID | |
Cytomap | 3p24.3 | |
Gene Type | protein-coding | GO ID | GO:0000003 | UniProtAcc | B5BUA4 |
Top |
Malignant transformation analysis |
![]() |
![]() |
Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
151648 | SGOL1 | P2T-E | Human | Esophagus | ESCC | 9.53e-09 | 2.36e-01 | 0.1177 |
151648 | SGOL1 | P4T-E | Human | Esophagus | ESCC | 1.22e-08 | 2.92e-01 | 0.1323 |
151648 | SGOL1 | P5T-E | Human | Esophagus | ESCC | 9.44e-07 | 1.81e-01 | 0.1327 |
151648 | SGOL1 | P9T-E | Human | Esophagus | ESCC | 3.05e-03 | 1.35e-01 | 0.1131 |
151648 | SGOL1 | P10T-E | Human | Esophagus | ESCC | 9.20e-06 | 1.63e-01 | 0.116 |
151648 | SGOL1 | P16T-E | Human | Esophagus | ESCC | 1.66e-02 | 8.37e-02 | 0.1153 |
151648 | SGOL1 | P21T-E | Human | Esophagus | ESCC | 1.88e-04 | 1.63e-01 | 0.1617 |
151648 | SGOL1 | P24T-E | Human | Esophagus | ESCC | 9.20e-06 | 2.11e-01 | 0.1287 |
151648 | SGOL1 | P28T-E | Human | Esophagus | ESCC | 8.56e-12 | 2.67e-01 | 0.1149 |
151648 | SGOL1 | P30T-E | Human | Esophagus | ESCC | 1.02e-02 | 2.02e-01 | 0.137 |
151648 | SGOL1 | P31T-E | Human | Esophagus | ESCC | 3.75e-03 | 1.27e-01 | 0.1251 |
151648 | SGOL1 | P32T-E | Human | Esophagus | ESCC | 4.31e-06 | 1.73e-01 | 0.1666 |
151648 | SGOL1 | P37T-E | Human | Esophagus | ESCC | 1.87e-02 | 1.03e-01 | 0.1371 |
151648 | SGOL1 | P38T-E | Human | Esophagus | ESCC | 3.67e-05 | 2.91e-01 | 0.127 |
151648 | SGOL1 | P42T-E | Human | Esophagus | ESCC | 3.05e-02 | 1.26e-01 | 0.1175 |
151648 | SGOL1 | P44T-E | Human | Esophagus | ESCC | 2.47e-02 | 1.30e-01 | 0.1096 |
151648 | SGOL1 | P52T-E | Human | Esophagus | ESCC | 8.84e-05 | 1.40e-01 | 0.1555 |
151648 | SGOL1 | P74T-E | Human | Esophagus | ESCC | 1.42e-04 | 2.29e-01 | 0.1479 |
151648 | SGOL1 | P75T-E | Human | Esophagus | ESCC | 1.96e-05 | 2.00e-01 | 0.1125 |
151648 | SGOL1 | P76T-E | Human | Esophagus | ESCC | 1.96e-05 | 2.47e-01 | 0.1207 |
Page: 1 2 3 |
![]() |
∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
Top |
Malignant transformation related pathway analysis |
![]() |
![]() |
Tissue | Disease Stage | Enriched GO biological Processes |
Liver | Cyst | ![]() |
Lung | IAC | ![]() |
Lung | AIS | ![]() |
Lung | AAH | ![]() |
Lung | MIAC | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
Page: 1 2 3 4 5 6 7 8 9 |
![]() |
GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
Page: 1 |
![]() |
Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
hsa041102 | Liver | HCC | Cell cycle | 106/4020 | 157/8465 | 2.54e-07 | 3.04e-06 | 1.69e-06 | 106 |
hsa041103 | Liver | HCC | Cell cycle | 106/4020 | 157/8465 | 2.54e-07 | 3.04e-06 | 1.69e-06 | 106 |
Page: 1 |
Top |
Cell-cell communication analysis |
![]() |
Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
Page: 1 |
Top |
Single-cell gene regulatory network inference analysis |
![]() |
TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
Page: 1 |
Top |
Somatic mutation of malignant transformation related genes |
![]() |
Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
Page: 1 |
Top |
Related drugs of malignant transformation related genes |
![]() |
(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
Page: 1 |