GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
GO:000641727 | Esophagus | HGIN | regulation of translation | 139/2587 | 468/18723 | 1.46e-19 | 7.98e-17 | 139 |
GO:000641320 | Esophagus | HGIN | translational initiation | 55/2587 | 118/18723 | 7.33e-18 | 2.31e-15 | 55 |
GO:004572720 | Esophagus | HGIN | positive regulation of translation | 49/2587 | 136/18723 | 5.88e-11 | 6.30e-09 | 49 |
GO:000644610 | Esophagus | HGIN | regulation of translational initiation | 34/2587 | 79/18723 | 2.09e-10 | 1.97e-08 | 34 |
GO:003425020 | Esophagus | HGIN | positive regulation of cellular amide metabolic process | 53/2587 | 162/18723 | 6.01e-10 | 5.15e-08 | 53 |
GO:0006413110 | Esophagus | ESCC | translational initiation | 100/8552 | 118/18723 | 1.16e-18 | 1.25e-16 | 100 |
GO:0006417111 | Esophagus | ESCC | regulation of translation | 304/8552 | 468/18723 | 1.53e-17 | 1.33e-15 | 304 |
GO:0045727111 | Esophagus | ESCC | positive regulation of translation | 107/8552 | 136/18723 | 2.79e-15 | 1.68e-13 | 107 |
GO:0034250111 | Esophagus | ESCC | positive regulation of cellular amide metabolic process | 123/8552 | 162/18723 | 3.32e-15 | 1.93e-13 | 123 |
GO:000644617 | Esophagus | ESCC | regulation of translational initiation | 65/8552 | 79/18723 | 2.04e-11 | 7.07e-10 | 65 |
GO:000641312 | Liver | Cirrhotic | translational initiation | 76/4634 | 118/18723 | 8.36e-20 | 2.18e-17 | 76 |
GO:000641712 | Liver | Cirrhotic | regulation of translation | 194/4634 | 468/18723 | 7.28e-16 | 8.79e-14 | 194 |
GO:00457277 | Liver | Cirrhotic | positive regulation of translation | 71/4634 | 136/18723 | 4.99e-12 | 3.52e-10 | 71 |
GO:000644612 | Liver | Cirrhotic | regulation of translational initiation | 48/4634 | 79/18723 | 1.14e-11 | 7.14e-10 | 48 |
GO:003425012 | Liver | Cirrhotic | positive regulation of cellular amide metabolic process | 78/4634 | 162/18723 | 8.62e-11 | 4.66e-09 | 78 |
GO:000641722 | Liver | HCC | regulation of translation | 287/7958 | 468/18723 | 8.79e-17 | 8.08e-15 | 287 |
GO:000641322 | Liver | HCC | translational initiation | 94/7958 | 118/18723 | 1.39e-16 | 1.24e-14 | 94 |
GO:004572712 | Liver | HCC | positive regulation of translation | 97/7958 | 136/18723 | 8.51e-12 | 3.55e-10 | 97 |
GO:003425022 | Liver | HCC | positive regulation of cellular amide metabolic process | 110/7958 | 162/18723 | 5.14e-11 | 1.92e-09 | 110 |
GO:000644622 | Liver | HCC | regulation of translational initiation | 62/7958 | 79/18723 | 6.85e-11 | 2.48e-09 | 62 |
Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
MIF4GD | SNV | Missense_Mutation | novel | c.257N>G | p.Ser86Cys | p.S86C | A9UHW6 | protein_coding | deleterious(0) | probably_damaging(0.995) | TCGA-5L-AAT1-01 | Breast | breast invasive carcinoma | Female | <65 | III/IV | Hormone Therapy | letrozol | SD |
MIF4GD | SNV | Missense_Mutation | | c.38N>A | p.Ser13Tyr | p.S13Y | A9UHW6 | protein_coding | deleterious_low_confidence(0) | possibly_damaging(0.713) | TCGA-A8-A09A-01 | Breast | breast invasive carcinoma | Female | <65 | I/II | Hormone Therapy | tamoxiphen | SD |
MIF4GD | SNV | Missense_Mutation | | c.130N>A | p.Glu44Lys | p.E44K | A9UHW6 | protein_coding | tolerated_low_confidence(0.4) | benign(0) | TCGA-AC-A23H-01 | Breast | breast invasive carcinoma | Female | >=65 | I/II | Unknown | Unknown | PD |
MIF4GD | insertion | Nonsense_Mutation | novel | c.36_37insGCAACGTAATTCTTGAACTGGAAGACAAGC | p.Gln12_Ser13insAlaThrTerPheLeuAsnTrpLysThrSer | p.Q12_S13insAT*FLNWKTS | A9UHW6 | protein_coding | | | TCGA-A8-A085-01 | Breast | breast invasive carcinoma | Male | <65 | I/II | Hormone Therapy | tamoxiphen | SD |
MIF4GD | insertion | Nonsense_Mutation | novel | c.718_719insCTGGCCATTTTCCCTCCTAAATGGTAGTCCTACCAAG | p.Ile240ThrfsTer7 | p.I240Tfs*7 | A9UHW6 | protein_coding | | | TCGA-AO-A0J9-01 | Breast | breast invasive carcinoma | Female | <65 | III/IV | Chemotherapy | cyclophosphamide | PD |
MIF4GD | SNV | Missense_Mutation | | c.245N>G | p.Ile82Ser | p.I82S | A9UHW6 | protein_coding | deleterious(0) | possibly_damaging(0.652) | TCGA-AA-3977-01 | Colorectum | colon adenocarcinoma | Male | >=65 | I/II | Unknown | Unknown | SD |
MIF4GD | SNV | Missense_Mutation | rs777781853 | c.139G>A | p.Val47Ile | p.V47I | A9UHW6 | protein_coding | tolerated_low_confidence(0.55) | benign(0) | TCGA-AZ-6600-01 | Colorectum | colon adenocarcinoma | Male | <65 | III/IV | Chemotherapy | cpt-11 | PD |
MIF4GD | SNV | Missense_Mutation | rs557030914 | c.698A>G | p.Gln233Arg | p.Q233R | A9UHW6 | protein_coding | tolerated(1) | benign(0.003) | TCGA-CM-5861-01 | Colorectum | colon adenocarcinoma | Female | <65 | I/II | Unknown | Unknown | PD |
MIF4GD | SNV | Missense_Mutation | | c.516C>A | p.Asp172Glu | p.D172E | A9UHW6 | protein_coding | tolerated(0.09) | benign(0.373) | TCGA-F4-6570-01 | Colorectum | colon adenocarcinoma | Female | >=65 | I/II | Unknown | Unknown | SD |
MIF4GD | SNV | Missense_Mutation | | c.53N>T | p.Thr18Ile | p.T18I | A9UHW6 | protein_coding | deleterious_low_confidence(0.02) | benign(0.042) | TCGA-AG-A002-01 | Colorectum | rectum adenocarcinoma | Male | <65 | I/II | Unknown | Unknown | SD |