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Gene: GPRC5D-AS1 |
Gene summary for GPRC5D-AS1 |
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Gene information | Species | Human | Gene symbol | GPRC5D-AS1 | Gene ID | 100506314 |
Gene name | GPRC5D and HEBP1 antisense RNA 1 | |
Gene Alias | GPRC5D-AS1 | |
Cytomap | 12p13.1 | |
Gene Type | ncRNA | GO ID | NA | UniProtAcc | NA |
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Malignant transformation analysis |
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Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
100506314 | GPRC5D-AS1 | TD9 | Human | Lung | IAC | 2.62e-11 | 1.14e+00 | 0.088 |
100506314 | GPRC5D-AS1 | RNA-P10T2-P10T2-3 | Human | Lung | AAH | 1.22e-02 | 6.79e-01 | -0.1408 |
100506314 | GPRC5D-AS1 | RNA-P10T2-P10T2-4 | Human | Lung | AAH | 5.54e-03 | 7.59e-01 | -0.138 |
100506314 | GPRC5D-AS1 | RNA-P17T-P17T-6 | Human | Lung | IAC | 1.48e-03 | 5.03e-01 | 0.3385 |
100506314 | GPRC5D-AS1 | RNA-P23T2-P23T2-2 | Human | Lung | MIAC | 1.30e-05 | 1.00e+00 | -0.028 |
100506314 | GPRC5D-AS1 | RNA-P25T1-P25T1-1 | Human | Lung | AIS | 1.69e-09 | 5.14e-01 | -0.2116 |
100506314 | GPRC5D-AS1 | RNA-P25T1-P25T1-3 | Human | Lung | AIS | 5.59e-05 | 5.26e-01 | -0.2107 |
100506314 | GPRC5D-AS1 | RNA-P25T1-P25T1-4 | Human | Lung | AIS | 3.15e-03 | 2.90e-01 | -0.2119 |
100506314 | GPRC5D-AS1 | RNA-P3T-P3T-1 | Human | Lung | IAC | 1.17e-04 | 5.25e-01 | 0.1829 |
100506314 | GPRC5D-AS1 | RNA-P3T-P3T-4 | Human | Lung | IAC | 2.70e-04 | 4.21e-01 | 0.1859 |
100506314 | GPRC5D-AS1 | RNA-P6T2-P6T2-1 | Human | Lung | IAC | 4.60e-03 | 1.89e-01 | -0.0166 |
100506314 | GPRC5D-AS1 | RNA-P6T2-P6T2-2 | Human | Lung | IAC | 1.88e-06 | 2.49e-01 | -0.0132 |
100506314 | GPRC5D-AS1 | RNA-P6T2-P6T2-3 | Human | Lung | IAC | 8.99e-07 | 2.72e-01 | -0.013 |
100506314 | GPRC5D-AS1 | RNA-P6T2-P6T2-4 | Human | Lung | IAC | 5.70e-05 | 2.74e-01 | -0.0121 |
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Tissue | Expression Dynamics | Abbreviation |
Lung | ![]() | AAH: Atypical adenomatous hyperplasia |
AIS: Adenocarcinoma in situ | ||
IAC: Invasive lung adenocarcinoma | ||
MIA: Minimally invasive adenocarcinoma |
∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
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Malignant transformation related pathway analysis |
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Tissue | Disease Stage | Enriched GO biological Processes |
Liver | Cyst | ![]() |
Lung | IAC | ![]() |
Lung | AIS | ![]() |
Lung | AAH | ![]() |
Lung | MIAC | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
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GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
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Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
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Cell-cell communication analysis |
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Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
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Single-cell gene regulatory network inference analysis |
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TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
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Somatic mutation of malignant transformation related genes |
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Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
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Related drugs of malignant transformation related genes |
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(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
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