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Gene: FAM195B |
Gene summary for FAM195B |
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Gene information | Species | Human | Gene symbol | FAM195B | Gene ID | 348262 |
Gene name | MAPK regulated corepressor interacting protein 1 | |
Gene Alias | FAM195B | |
Cytomap | 17q25.3 | |
Gene Type | protein-coding | GO ID | GO:0001837 | UniProtAcc | A0A024R8R5 |
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Malignant transformation analysis |
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Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
348262 | FAM195B | P1T-E | Human | Esophagus | ESCC | 5.20e-08 | 3.48e-01 | 0.0875 |
348262 | FAM195B | P2T-E | Human | Esophagus | ESCC | 3.33e-67 | 1.03e+00 | 0.1177 |
348262 | FAM195B | P4T-E | Human | Esophagus | ESCC | 8.87e-34 | 7.14e-01 | 0.1323 |
348262 | FAM195B | P5T-E | Human | Esophagus | ESCC | 3.22e-45 | 7.53e-01 | 0.1327 |
348262 | FAM195B | P8T-E | Human | Esophagus | ESCC | 2.02e-60 | 9.80e-01 | 0.0889 |
348262 | FAM195B | P9T-E | Human | Esophagus | ESCC | 1.67e-23 | 5.16e-01 | 0.1131 |
348262 | FAM195B | P10T-E | Human | Esophagus | ESCC | 1.14e-66 | 1.02e+00 | 0.116 |
348262 | FAM195B | P11T-E | Human | Esophagus | ESCC | 8.76e-55 | 1.79e+00 | 0.1426 |
348262 | FAM195B | P12T-E | Human | Esophagus | ESCC | 9.14e-50 | 8.45e-01 | 0.1122 |
348262 | FAM195B | P15T-E | Human | Esophagus | ESCC | 1.30e-46 | 8.62e-01 | 0.1149 |
348262 | FAM195B | P16T-E | Human | Esophagus | ESCC | 6.26e-61 | 9.99e-01 | 0.1153 |
348262 | FAM195B | P17T-E | Human | Esophagus | ESCC | 1.71e-24 | 9.14e-01 | 0.1278 |
348262 | FAM195B | P19T-E | Human | Esophagus | ESCC | 4.55e-30 | 1.38e+00 | 0.1662 |
348262 | FAM195B | P20T-E | Human | Esophagus | ESCC | 3.34e-60 | 1.17e+00 | 0.1124 |
348262 | FAM195B | P21T-E | Human | Esophagus | ESCC | 1.79e-70 | 1.24e+00 | 0.1617 |
348262 | FAM195B | P22T-E | Human | Esophagus | ESCC | 5.53e-63 | 9.46e-01 | 0.1236 |
348262 | FAM195B | P23T-E | Human | Esophagus | ESCC | 7.50e-29 | 6.04e-01 | 0.108 |
348262 | FAM195B | P24T-E | Human | Esophagus | ESCC | 1.85e-55 | 9.29e-01 | 0.1287 |
348262 | FAM195B | P26T-E | Human | Esophagus | ESCC | 2.20e-48 | 8.35e-01 | 0.1276 |
348262 | FAM195B | P27T-E | Human | Esophagus | ESCC | 5.95e-29 | 5.11e-01 | 0.1055 |
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∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
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Malignant transformation related pathway analysis |
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Tissue | Disease Stage | Enriched GO biological Processes |
Liver | Cyst | ![]() |
Lung | IAC | ![]() |
Lung | AIS | ![]() |
Lung | AAH | ![]() |
Lung | MIAC | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
Page: 1 2 3 4 5 6 7 8 9 |
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GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
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Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
Page: 1 |
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Cell-cell communication analysis |
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Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
Page: 1 |
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Single-cell gene regulatory network inference analysis |
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TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
Page: 1 |
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Somatic mutation of malignant transformation related genes |
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Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
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Related drugs of malignant transformation related genes |
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(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
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