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Gene: EGOT |
Gene summary for EGOT |
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Gene information | Species | Human | Gene symbol | EGOT | Gene ID | 100126791 |
Gene name | eosinophil granule ontogeny transcript | |
Gene Alias | EGO | |
Cytomap | 3p26.1 | |
Gene Type | ncRNA | GO ID | NA | UniProtAcc | NA |
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Malignant transformation analysis |
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Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
100126791 | EGOT | P1T-E | Human | Esophagus | ESCC | 1.41e-06 | 2.78e-01 | 0.0875 |
100126791 | EGOT | P2T-E | Human | Esophagus | ESCC | 2.34e-09 | 1.92e-01 | 0.1177 |
100126791 | EGOT | P5T-E | Human | Esophagus | ESCC | 1.15e-04 | 1.05e-01 | 0.1327 |
100126791 | EGOT | P8T-E | Human | Esophagus | ESCC | 2.97e-05 | 1.78e-02 | 0.0889 |
100126791 | EGOT | P23T-E | Human | Esophagus | ESCC | 1.25e-05 | 5.87e-01 | 0.108 |
100126791 | EGOT | P24T-E | Human | Esophagus | ESCC | 2.39e-04 | 7.95e-02 | 0.1287 |
100126791 | EGOT | P32T-E | Human | Esophagus | ESCC | 3.43e-03 | -3.19e-02 | 0.1666 |
100126791 | EGOT | P36T-E | Human | Esophagus | ESCC | 8.70e-16 | 7.83e-01 | 0.1187 |
100126791 | EGOT | P37T-E | Human | Esophagus | ESCC | 2.29e-07 | 2.28e-01 | 0.1371 |
100126791 | EGOT | P48T-E | Human | Esophagus | ESCC | 1.61e-06 | 1.58e-01 | 0.0959 |
100126791 | EGOT | P52T-E | Human | Esophagus | ESCC | 6.79e-06 | 1.91e-01 | 0.1555 |
100126791 | EGOT | P57T-E | Human | Esophagus | ESCC | 5.13e-10 | 1.66e-01 | 0.0926 |
100126791 | EGOT | P62T-E | Human | Esophagus | ESCC | 3.46e-05 | 8.56e-02 | 0.1302 |
100126791 | EGOT | P80T-E | Human | Esophagus | ESCC | 5.15e-16 | 5.15e-01 | 0.155 |
100126791 | EGOT | P130T-E | Human | Esophagus | ESCC | 7.55e-12 | 1.41e-01 | 0.1676 |
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Tissue | Expression Dynamics | Abbreviation |
Esophagus | ![]() | ESCC: Esophageal squamous cell carcinoma |
HGIN: High-grade intraepithelial neoplasias | ||
LGIN: Low-grade intraepithelial neoplasias |
∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
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Malignant transformation related pathway analysis |
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Tissue | Disease Stage | Enriched GO biological Processes |
Liver | Cyst | ![]() |
Lung | IAC | ![]() |
Lung | AIS | ![]() |
Lung | AAH | ![]() |
Lung | MIAC | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
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GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
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Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
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Cell-cell communication analysis |
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Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
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Single-cell gene regulatory network inference analysis |
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TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
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Somatic mutation of malignant transformation related genes |
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Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
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Related drugs of malignant transformation related genes |
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(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
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