GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
GO:00219159 | Esophagus | ESCC | neural tube development | 101/8552 | 152/18723 | 1.78e-07 | 2.79e-06 | 101 |
GO:0051098113 | Thyroid | PTC | regulation of binding | 195/5968 | 363/18723 | 3.21e-18 | 3.37e-16 | 195 |
GO:0045185113 | Thyroid | PTC | maintenance of protein location | 64/5968 | 94/18723 | 5.92e-13 | 2.85e-11 | 64 |
GO:0031346110 | Thyroid | PTC | positive regulation of cell projection organization | 173/5968 | 353/18723 | 1.09e-11 | 4.40e-10 | 173 |
GO:0043393111 | Thyroid | PTC | regulation of protein binding | 103/5968 | 196/18723 | 1.39e-09 | 3.96e-08 | 103 |
GO:0051235112 | Thyroid | PTC | maintenance of location | 148/5968 | 327/18723 | 2.30e-07 | 4.07e-06 | 148 |
GO:0120032111 | Thyroid | PTC | regulation of plasma membrane bounded cell projection assembly | 92/5968 | 186/18723 | 4.12e-07 | 6.83e-06 | 92 |
GO:006049120 | Thyroid | PTC | regulation of cell projection assembly | 92/5968 | 188/18723 | 7.55e-07 | 1.18e-05 | 92 |
GO:01200349 | Thyroid | PTC | positive regulation of plasma membrane bounded cell projection assembly | 57/5968 | 105/18723 | 1.60e-06 | 2.25e-05 | 57 |
GO:190211516 | Thyroid | PTC | regulation of organelle assembly | 88/5968 | 186/18723 | 7.41e-06 | 8.65e-05 | 88 |
GO:19021176 | Thyroid | PTC | positive regulation of organelle assembly | 35/5968 | 67/18723 | 4.24e-04 | 2.83e-03 | 35 |
GO:00512207 | Thyroid | PTC | cytoplasmic sequestering of protein | 15/5968 | 22/18723 | 5.11e-04 | 3.32e-03 | 15 |
GO:005109834 | Thyroid | ATC | regulation of binding | 203/6293 | 363/18723 | 1.18e-18 | 1.55e-16 | 203 |
GO:003134623 | Thyroid | ATC | positive regulation of cell projection organization | 186/6293 | 353/18723 | 7.99e-14 | 4.23e-12 | 186 |
GO:004518532 | Thyroid | ATC | maintenance of protein location | 64/6293 | 94/18723 | 8.44e-12 | 3.16e-10 | 64 |
GO:004339327 | Thyroid | ATC | regulation of protein binding | 110/6293 | 196/18723 | 6.99e-11 | 2.22e-09 | 110 |
GO:012003414 | Thyroid | ATC | positive regulation of plasma membrane bounded cell projection assembly | 60/6293 | 105/18723 | 6.10e-07 | 8.47e-06 | 60 |
GO:012003223 | Thyroid | ATC | regulation of plasma membrane bounded cell projection assembly | 95/6293 | 186/18723 | 6.13e-07 | 8.49e-06 | 95 |
GO:005123532 | Thyroid | ATC | maintenance of location | 152/6293 | 327/18723 | 7.84e-07 | 1.04e-05 | 152 |
GO:0060491111 | Thyroid | ATC | regulation of cell projection assembly | 95/6293 | 188/18723 | 1.14e-06 | 1.47e-05 | 95 |
Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
DZIP1 | SNV | Missense_Mutation | rs138320927 | c.954N>T | p.Lys318Asn | p.K318N | Q86YF9 | protein_coding | deleterious(0) | probably_damaging(0.922) | TCGA-AN-A046-01 | Breast | breast invasive carcinoma | Female | >=65 | I/II | Unknown | Unknown | SD |
DZIP1 | SNV | Missense_Mutation | rs147653120 | c.2494N>A | p.Ala832Thr | p.A832T | Q86YF9 | protein_coding | tolerated(0.32) | benign(0.003) | TCGA-GM-A3NW-01 | Breast | breast invasive carcinoma | Female | <65 | I/II | Chemotherapy | fluorouracil | SD |
DZIP1 | insertion | Frame_Shift_Ins | novel | c.2091_2092insTTGGAAAACTCTCTGGAAACTGTATTTAGGACAGTTGTCCTCA | p.Pro698LeufsTer37 | p.P698Lfs*37 | Q86YF9 | protein_coding | | | TCGA-A2-A0EQ-01 | Breast | breast invasive carcinoma | Female | <65 | I/II | Chemotherapy | adriamycin | SD |
DZIP1 | SNV | Missense_Mutation | | c.1033N>C | p.Asp345His | p.D345H | Q86YF9 | protein_coding | deleterious(0) | probably_damaging(0.999) | TCGA-C5-A1BJ-01 | Cervix | cervical & endocervical cancer | Female | <65 | I/II | Unknown | Unknown | SD |
DZIP1 | SNV | Missense_Mutation | novel | c.344N>T | p.Pro115Leu | p.P115L | Q86YF9 | protein_coding | deleterious(0) | probably_damaging(1) | TCGA-C5-A1ME-01 | Cervix | cervical & endocervical cancer | Female | <65 | I/II | Unknown | Unknown | SD |
DZIP1 | SNV | Missense_Mutation | | c.2578G>A | p.Asp860Asn | p.D860N | Q86YF9 | protein_coding | deleterious(0) | possibly_damaging(0.817) | TCGA-EK-A2PG-01 | Cervix | cervical & endocervical cancer | Female | >=65 | I/II | Unknown | Unknown | SD |
DZIP1 | SNV | Missense_Mutation | | c.406G>C | p.Glu136Gln | p.E136Q | Q86YF9 | protein_coding | deleterious(0) | probably_damaging(0.993) | TCGA-IR-A3LI-01 | Cervix | cervical & endocervical cancer | Female | <65 | I/II | Chemotherapy | cisplatin | CR |
DZIP1 | SNV | Missense_Mutation | rs770171062 | c.2053N>A | p.Glu685Lys | p.E685K | Q86YF9 | protein_coding | deleterious(0) | possibly_damaging(0.498) | TCGA-JW-A5VL-01 | Cervix | cervical & endocervical cancer | Female | <65 | I/II | Unknown | Unknown | SD |
DZIP1 | SNV | Missense_Mutation | novel | c.1394N>G | p.Ser465Cys | p.S465C | Q86YF9 | protein_coding | deleterious(0.02) | benign(0.111) | TCGA-MA-AA3Y-01 | Cervix | cervical & endocervical cancer | Female | <65 | I/II | Unknown | Unknown | SD |
DZIP1 | deletion | Frame_Shift_Del | novel | c.2027delN | p.Thr676ArgfsTer42 | p.T676Rfs*42 | Q86YF9 | protein_coding | | | TCGA-LP-A7HU-01 | Cervix | cervical & endocervical cancer | Female | <65 | I/II | Unknown | Unknown | SD |