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Gene: C19orf77 |
Gene summary for C19ORF77 |
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Gene information | Species | Human | Gene symbol | C19orf77 | Gene ID | 284422 |
Gene name | small integral membrane protein 24 | |
Gene Alias | C19orf77 | |
Cytomap | 19p13.3 | |
Gene Type | protein-coding | GO ID | GO:0008150 | UniProtAcc | O75264 |
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Malignant transformation analysis |
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Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
284422 | C19orf77 | NAG_1 | Human | Stomach | CSG | 8.83e-18 | 5.75e-01 | -0.3534 |
284422 | C19orf77 | NAG_2 | Human | Stomach | CSG | 2.19e-23 | 7.29e-01 | -0.3324 |
284422 | C19orf77 | NAG_3 | Human | Stomach | CSG | 1.65e-15 | 6.68e-01 | -0.2816 |
284422 | C19orf77 | CAG_1 | Human | Stomach | CAG | 1.56e-05 | 4.65e-01 | -0.3206 |
284422 | C19orf77 | CAG_2 | Human | Stomach | CAG | 9.39e-08 | 3.26e-01 | -0.2831 |
284422 | C19orf77 | CAG_3 | Human | Stomach | CAG | 1.87e-26 | 6.62e-01 | -0.2766 |
284422 | C19orf77 | WIM_1 | Human | Stomach | WIM | 3.14e-21 | 7.21e-01 | 0.0335 |
284422 | C19orf77 | WIM_2 | Human | Stomach | WIM | 6.77e-26 | 8.86e-01 | 0.1159 |
284422 | C19orf77 | SIM_1 | Human | Stomach | SIM | 1.20e-54 | 1.21e+00 | 0.3573 |
284422 | C19orf77 | SIM_2 | Human | Stomach | SIM | 4.29e-57 | 1.13e+00 | 0.3139 |
284422 | C19orf77 | SIM_3 | Human | Stomach | SIM | 5.01e-14 | 5.37e-01 | 0.0345 |
284422 | C19orf77 | SIM_4 | Human | Stomach | SIM | 1.48e-42 | 1.07e+00 | 0.2664 |
284422 | C19orf77 | EGC | Human | Stomach | GC | 2.40e-16 | 5.13e-01 | 0.1683 |
284422 | C19orf77 | Pt1_Superficial | Human | Stomach | GC | 2.54e-15 | 6.47e-01 | 0.1036 |
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∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
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Malignant transformation related pathway analysis |
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Tissue | Disease Stage | Enriched GO biological Processes |
Liver | Cyst | ![]() |
Lung | IAC | ![]() |
Lung | AIS | ![]() |
Lung | AAH | ![]() |
Lung | MIAC | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
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GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
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Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
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Cell-cell communication analysis |
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Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
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Single-cell gene regulatory network inference analysis |
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TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
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Somatic mutation of malignant transformation related genes |
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Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
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Related drugs of malignant transformation related genes |
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(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
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