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Gene: ATHL1 |
Gene summary for ATHL1 |
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Gene information | Species | Human | Gene symbol | ATHL1 | Gene ID | 80162 |
Gene name | protein-glucosylgalactosylhydroxylysine glucosidase | |
Gene Alias | ATHL1 | |
Cytomap | 11p15.5 | |
Gene Type | protein-coding | GO ID | GO:0005975 | UniProtAcc | A0A024R1Z9 |
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Malignant transformation analysis |
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Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
80162 | ATHL1 | Dong_P3 | Human | Prostate | Tumor | 7.74e-08 | 1.30e-01 | 0.0278 |
80162 | ATHL1 | P9 | Human | Prostate | Tumor | 3.26e-11 | 4.30e-01 | -0.0285 |
80162 | ATHL1 | GSM5353221_PA_PB2A_Pool_1_3_S25_L001 | Human | Prostate | Tumor | 9.88e-13 | 5.20e-01 | 0.1633 |
80162 | ATHL1 | GSM5353222_PA_PB2B_Pool_1_3_S52_L002 | Human | Prostate | Tumor | 1.32e-17 | 6.11e-01 | 0.1608 |
80162 | ATHL1 | GSM5353223_PA_PB2B_Pool_2_S26_L001 | Human | Prostate | Tumor | 3.75e-15 | 5.66e-01 | 0.1604 |
80162 | ATHL1 | GSM5353224_PA_PR5186_Pool_1_2_3_S27_L001 | Human | Prostate | Tumor | 9.65e-13 | 4.94e-01 | 0.1621 |
80162 | ATHL1 | GSM5353225_PA_PR5196-1_Pool_1_2_3_S53_L002 | Human | Prostate | Tumor | 3.27e-04 | 4.52e-01 | 0.1619 |
80162 | ATHL1 | GSM5353227_PA_PR5199-193K_Pool_1_2_3_S55_L002 | Human | Prostate | Tumor | 4.57e-13 | 5.68e-01 | 0.1602 |
80162 | ATHL1 | GSM5353228_PA_PR5199-640K_Pool_1_3_S108_L004 | Human | Prostate | Tumor | 7.07e-03 | 7.27e-01 | 0.1537 |
80162 | ATHL1 | GSM5353236_PA_PR5251_T1_S7_L001 | Human | Prostate | Tumor | 5.51e-03 | 2.91e-01 | 0.1608 |
80162 | ATHL1 | GSM5353237_PA_PR5251_T2_S8_L001 | Human | Prostate | Tumor | 2.91e-04 | 4.04e-01 | 0.1622 |
80162 | ATHL1 | GSM5353240_PA_PR5254_T1_S15_L001 | Human | Prostate | Tumor | 5.08e-12 | 4.35e-01 | 0.1575 |
80162 | ATHL1 | GSM5353243_PA_PR5261_T1_S23_L002 | Human | Prostate | Tumor | 1.66e-03 | 2.74e-01 | 0.1545 |
80162 | ATHL1 | GSM5353244_PA_PR5261_T2_S24_L002 | Human | Prostate | Tumor | 7.66e-05 | 2.91e-01 | 0.1569 |
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Tissue | Expression Dynamics | Abbreviation |
Prostate | ![]() | BPH: Benign Prostatic Hyperplasia |
∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
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Malignant transformation related pathway analysis |
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Tissue | Disease Stage | Enriched GO biological Processes |
Liver | Cyst | ![]() |
Lung | IAC | ![]() |
Lung | AIS | ![]() |
Lung | AAH | ![]() |
Lung | MIAC | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
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GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
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Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
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Cell-cell communication analysis |
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Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
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Single-cell gene regulatory network inference analysis |
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TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
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Somatic mutation of malignant transformation related genes |
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Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
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Related drugs of malignant transformation related genes |
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(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
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