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Gene: ZBTB5 |
Gene summary for ZBTB5 |
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Gene information | Species | Human | Gene symbol | ZBTB5 | Gene ID | 9925 |
Gene name | zinc finger and BTB domain containing 5 | |
Gene Alias | ZBTB5 | |
Cytomap | 9p13.2 | |
Gene Type | protein-coding | GO ID | GO:0000122 | UniProtAcc | O15062 |
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Malignant transformation analysis |
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Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
9925 | ZBTB5 | LZE4T | Human | Esophagus | ESCC | 9.36e-06 | 2.15e-01 | 0.0811 |
9925 | ZBTB5 | LZE7T | Human | Esophagus | ESCC | 1.65e-06 | 3.14e-01 | 0.0667 |
9925 | ZBTB5 | LZE8T | Human | Esophagus | ESCC | 2.65e-04 | 1.53e-01 | 0.067 |
9925 | ZBTB5 | LZE24T | Human | Esophagus | ESCC | 2.08e-08 | 1.48e-01 | 0.0596 |
9925 | ZBTB5 | P2T-E | Human | Esophagus | ESCC | 8.67e-14 | 2.61e-01 | 0.1177 |
9925 | ZBTB5 | P4T-E | Human | Esophagus | ESCC | 3.18e-02 | 7.18e-02 | 0.1323 |
9925 | ZBTB5 | P9T-E | Human | Esophagus | ESCC | 3.39e-05 | 7.12e-02 | 0.1131 |
9925 | ZBTB5 | P10T-E | Human | Esophagus | ESCC | 1.38e-06 | 1.22e-01 | 0.116 |
9925 | ZBTB5 | P12T-E | Human | Esophagus | ESCC | 5.35e-12 | 1.02e-01 | 0.1122 |
9925 | ZBTB5 | P15T-E | Human | Esophagus | ESCC | 1.59e-04 | 1.09e-01 | 0.1149 |
9925 | ZBTB5 | P16T-E | Human | Esophagus | ESCC | 8.69e-04 | 6.65e-02 | 0.1153 |
9925 | ZBTB5 | P21T-E | Human | Esophagus | ESCC | 3.47e-04 | 3.82e-02 | 0.1617 |
9925 | ZBTB5 | P22T-E | Human | Esophagus | ESCC | 2.16e-03 | 3.52e-02 | 0.1236 |
9925 | ZBTB5 | P24T-E | Human | Esophagus | ESCC | 9.27e-03 | 4.86e-02 | 0.1287 |
9925 | ZBTB5 | P26T-E | Human | Esophagus | ESCC | 2.61e-05 | 1.05e-01 | 0.1276 |
9925 | ZBTB5 | P27T-E | Human | Esophagus | ESCC | 5.07e-05 | 7.08e-02 | 0.1055 |
9925 | ZBTB5 | P28T-E | Human | Esophagus | ESCC | 3.11e-22 | 5.10e-01 | 0.1149 |
9925 | ZBTB5 | P31T-E | Human | Esophagus | ESCC | 6.31e-08 | 4.62e-02 | 0.1251 |
9925 | ZBTB5 | P32T-E | Human | Esophagus | ESCC | 4.22e-09 | 8.63e-02 | 0.1666 |
9925 | ZBTB5 | P36T-E | Human | Esophagus | ESCC | 1.26e-06 | 1.22e-01 | 0.1187 |
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Tissue | Expression Dynamics | Abbreviation |
∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
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Malignant transformation related pathway analysis |
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Tissue | Disease Stage | Enriched GO biological Processes |
Stomach | WIM | ![]() |
Stomach | SIM | ![]() |
Liver | NAFLD | ![]() |
Liver | Cirrhotic | ![]() |
Liver | HCC | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
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GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
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Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
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Cell-cell communication analysis |
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Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
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Single-cell gene regulatory network inference analysis |
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∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
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Somatic mutation of malignant transformation related genes |
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Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
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Related drugs of malignant transformation related genes |
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(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
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