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Gene: SMIM2-AS1 |
Gene summary for SMIM2-AS1 |
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Gene information | Species | Human | Gene symbol | SMIM2-AS1 | Gene ID | 101929212 |
Gene name | SMIM2 antisense RNA 1 | |
Gene Alias | C13orf44-AS1 | |
Cytomap | 13q14.11 | |
Gene Type | ncRNA | GO ID | NA | UniProtAcc | NA |
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Malignant transformation analysis |
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Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
101929212 | SMIM2-AS1 | HTA11_347_2000001011 | Human | Colorectum | AD | 3.26e-02 | 2.49e-01 | -0.1954 |
101929212 | SMIM2-AS1 | HTA11_99999965104_69814 | Human | Colorectum | MSS | 2.24e-11 | 5.72e-01 | 0.281 |
101929212 | SMIM2-AS1 | F072B | Human | Colorectum | FAP | 1.42e-18 | 7.51e-01 | 0.257 |
101929212 | SMIM2-AS1 | HCC1_Meng | Human | Liver | HCC | 2.88e-22 | 1.61e-02 | 0.0246 |
101929212 | SMIM2-AS1 | S027 | Human | Liver | HCC | 2.94e-04 | 6.87e-01 | 0.2446 |
101929212 | SMIM2-AS1 | S028 | Human | Liver | HCC | 1.03e-16 | 8.04e-01 | 0.2503 |
101929212 | SMIM2-AS1 | S029 | Human | Liver | HCC | 3.33e-17 | 8.38e-01 | 0.2581 |
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∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
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Malignant transformation related pathway analysis |
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Tissue | Disease Stage | Enriched GO biological Processes |
Stomach | WIM | ![]() |
Stomach | SIM | ![]() |
Liver | NAFLD | ![]() |
Liver | Cirrhotic | ![]() |
Liver | HCC | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
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GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
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Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
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Cell-cell communication analysis |
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Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
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Single-cell gene regulatory network inference analysis |
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TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
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Somatic mutation of malignant transformation related genes |
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Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
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Related drugs of malignant transformation related genes |
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(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
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