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Gene: SERPINI2 |
Gene summary for SERPINI2 |
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Gene information | Species | Human | Gene symbol | SERPINI2 | Gene ID | 5276 |
Gene name | serpin family I member 2 | |
Gene Alias | MEPI | |
Cytomap | 3q26.1 | |
Gene Type | protein-coding | GO ID | GO:0006508 | UniProtAcc | A0A0C4DGW9 |
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Malignant transformation analysis |
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Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
5276 | SERPINI2 | HTA12-29-1 | Human | Pancreas | PDAC | 2.25e-08 | -6.11e-01 | 0.3722 |
5276 | SERPINI2 | HTA12-9-1 | Human | Pancreas | PDAC | 2.22e-08 | -7.62e-01 | 0.1532 |
5276 | SERPINI2 | HTA12-9-3 | Human | Pancreas | PDAC | 4.30e-02 | -7.62e-01 | 0.2045 |
5276 | SERPINI2 | 3829-EC | Human | Pancreas | PanIN | 6.45e-09 | -1.99e-01 | 0.009 |
5276 | SERPINI2 | 4347-EC | Human | Pancreas | PanIN | 3.30e-20 | -6.34e-01 | 0.0572 |
5276 | SERPINI2 | DS20191261Tumor | Human | Pancreas | PDAC | 1.81e-10 | -7.62e-01 | 0.1367 |
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Tissue | Expression Dynamics | Abbreviation |
∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
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Malignant transformation related pathway analysis |
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Tissue | Disease Stage | Enriched GO biological Processes |
Stomach | WIM | ![]() |
Stomach | SIM | ![]() |
Liver | NAFLD | ![]() |
Liver | Cirrhotic | ![]() |
Liver | HCC | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
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GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
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Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
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Cell-cell communication analysis |
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Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
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Single-cell gene regulatory network inference analysis |
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TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
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Somatic mutation of malignant transformation related genes |
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Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
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Related drugs of malignant transformation related genes |
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(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
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