![]() |
|||||
|
![]() | |
![]() | |
![]() | |
![]() | |
![]() | |
![]() | |
![]() |
Gene: MORN2 |
Gene summary for MORN2 |
![]() |
Gene information | Species | Human | Gene symbol | MORN2 | Gene ID | 729967 |
Gene name | MORN repeat containing 2 | |
Gene Alias | BLOCK27 | |
Cytomap | 2p22.1 | |
Gene Type | protein-coding | GO ID | GO:0000003 | UniProtAcc | Q502X0 |
Top |
Malignant transformation analysis |
![]() |
![]() |
Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
729967 | MORN2 | LZE4T | Human | Esophagus | ESCC | 2.24e-08 | 2.34e-01 | 0.0811 |
729967 | MORN2 | LZE7T | Human | Esophagus | ESCC | 1.04e-07 | 3.22e-01 | 0.0667 |
729967 | MORN2 | LZE8T | Human | Esophagus | ESCC | 1.76e-07 | 2.04e-01 | 0.067 |
729967 | MORN2 | LZE20T | Human | Esophagus | ESCC | 2.82e-03 | 1.26e-01 | 0.0662 |
729967 | MORN2 | LZE22T | Human | Esophagus | ESCC | 3.23e-03 | 2.43e-01 | 0.068 |
729967 | MORN2 | LZE24T | Human | Esophagus | ESCC | 4.37e-09 | 6.95e-01 | 0.0596 |
729967 | MORN2 | LZE6T | Human | Esophagus | ESCC | 2.56e-13 | 5.58e-01 | 0.0845 |
729967 | MORN2 | P1T-E | Human | Esophagus | ESCC | 4.46e-06 | 4.02e-01 | 0.0875 |
729967 | MORN2 | P2T-E | Human | Esophagus | ESCC | 5.15e-63 | 1.03e+00 | 0.1177 |
729967 | MORN2 | P4T-E | Human | Esophagus | ESCC | 9.06e-34 | 5.80e-01 | 0.1323 |
729967 | MORN2 | P5T-E | Human | Esophagus | ESCC | 9.59e-16 | 3.85e-01 | 0.1327 |
729967 | MORN2 | P8T-E | Human | Esophagus | ESCC | 5.74e-19 | 4.12e-01 | 0.0889 |
729967 | MORN2 | P9T-E | Human | Esophagus | ESCC | 1.06e-16 | 3.65e-01 | 0.1131 |
729967 | MORN2 | P10T-E | Human | Esophagus | ESCC | 1.04e-26 | 5.41e-01 | 0.116 |
729967 | MORN2 | P11T-E | Human | Esophagus | ESCC | 9.77e-16 | 5.48e-01 | 0.1426 |
729967 | MORN2 | P12T-E | Human | Esophagus | ESCC | 3.72e-20 | 4.49e-01 | 0.1122 |
729967 | MORN2 | P15T-E | Human | Esophagus | ESCC | 1.23e-23 | 5.41e-01 | 0.1149 |
729967 | MORN2 | P16T-E | Human | Esophagus | ESCC | 7.85e-51 | 8.60e-01 | 0.1153 |
729967 | MORN2 | P17T-E | Human | Esophagus | ESCC | 1.52e-10 | 4.29e-01 | 0.1278 |
729967 | MORN2 | P19T-E | Human | Esophagus | ESCC | 3.83e-11 | 7.42e-01 | 0.1662 |
Page: 1 2 3 4 5 6 7 |
![]() |
∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
Top |
Malignant transformation related pathway analysis |
![]() |
![]() |
Tissue | Disease Stage | Enriched GO biological Processes |
Stomach | WIM | ![]() |
Stomach | SIM | ![]() |
Liver | NAFLD | ![]() |
Liver | Cirrhotic | ![]() |
Liver | HCC | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
Page: 1 2 3 4 5 6 7 8 9 |
![]() |
GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
Page: 1 |
![]() |
Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
Page: 1 |
Top |
Cell-cell communication analysis |
![]() |
Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
Page: 1 |
Top |
Single-cell gene regulatory network inference analysis |
![]() |
TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
Page: 1 |
Top |
Somatic mutation of malignant transformation related genes |
![]() |
Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
MORN2 | SNV | Missense_Mutation | novel | c.223N>G | p.Leu75Val | p.L75V | Q502X0 | protein_coding | tolerated(0.28) | benign(0.194) | TCGA-F5-6814-01 | Colorectum | rectum adenocarcinoma | Male | <65 | I/II | Unknown | Unknown | SD |
MORN2 | insertion | Frame_Shift_Ins | novel | c.106dupG | p.Ala36GlyfsTer9 | p.A36Gfs*9 | Q502X0 | protein_coding | TCGA-D5-6530-01 | Colorectum | colon adenocarcinoma | Male | <65 | I/II | Unknown | Unknown | SD | ||
MORN2 | SNV | Missense_Mutation | novel | c.24N>T | p.Glu8Asp | p.E8D | Q502X0 | protein_coding | tolerated(0.12) | benign(0.073) | TCGA-AX-A1CE-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | <65 | I/II | Unspecific | Paclitaxel | SD |
Page: 1 |
Top |
Related drugs of malignant transformation related genes |
![]() |
(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
Page: 1 |