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Gene: IQCN |
Gene summary for IQCN |
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Gene information | Species | Human | Gene symbol | IQCN | Gene ID | 80726 |
Gene name | IQ motif containing N | |
Gene Alias | KIAA1683 | |
Cytomap | 19p13.11 | |
Gene Type | protein-coding | GO ID | GO:0005575 | UniProtAcc | Q9H0B3 |
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Malignant transformation analysis |
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Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
80726 | IQCN | AEH-subject1 | Human | Endometrium | AEH | 5.79e-15 | 2.87e-01 | -0.3059 |
80726 | IQCN | AEH-subject2 | Human | Endometrium | AEH | 6.11e-10 | 3.23e-01 | -0.2525 |
80726 | IQCN | AEH-subject3 | Human | Endometrium | AEH | 3.99e-06 | 2.06e-01 | -0.2576 |
80726 | IQCN | AEH-subject4 | Human | Endometrium | AEH | 9.74e-11 | 3.21e-01 | -0.2657 |
80726 | IQCN | EEC-subject1 | Human | Endometrium | EEC | 1.14e-15 | 3.92e-01 | -0.2682 |
80726 | IQCN | EEC-subject2 | Human | Endometrium | EEC | 4.01e-09 | 2.44e-01 | -0.2607 |
80726 | IQCN | EEC-subject4 | Human | Endometrium | EEC | 1.85e-09 | 3.10e-01 | -0.2571 |
80726 | IQCN | GSM5276935 | Human | Endometrium | EEC | 1.56e-02 | 7.40e-02 | -0.123 |
80726 | IQCN | GSM6177623_NYU_UCEC3_Vis | Human | Endometrium | EEC | 7.12e-13 | 3.01e-01 | -0.1269 |
80726 | IQCN | PTC01 | Human | Thyroid | PTC | 2.43e-03 | 1.10e-01 | 0.1899 |
80726 | IQCN | PTC04 | Human | Thyroid | PTC | 5.43e-04 | 1.22e-01 | 0.1927 |
80726 | IQCN | PTC06 | Human | Thyroid | PTC | 9.51e-09 | 2.44e-01 | 0.2057 |
80726 | IQCN | PTC07 | Human | Thyroid | PTC | 1.04e-12 | 2.76e-01 | 0.2044 |
80726 | IQCN | ATC13 | Human | Thyroid | ATC | 6.62e-35 | 6.35e-01 | 0.34 |
80726 | IQCN | ATC5 | Human | Thyroid | ATC | 7.27e-33 | 6.81e-01 | 0.34 |
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∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
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Malignant transformation related pathway analysis |
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Tissue | Disease Stage | Enriched GO biological Processes |
Stomach | WIM | ![]() |
Stomach | SIM | ![]() |
Liver | NAFLD | ![]() |
Liver | Cirrhotic | ![]() |
Liver | HCC | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
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GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
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Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
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Cell-cell communication analysis |
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Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
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Single-cell gene regulatory network inference analysis |
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TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
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Somatic mutation of malignant transformation related genes |
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Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
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Related drugs of malignant transformation related genes |
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(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
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