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Gene: IQCM |
Gene summary for IQCM |
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Gene information | Species | Human | Gene symbol | IQCM | Gene ID | 285423 |
Gene name | IQ motif containing M | |
Gene Alias | IQCM | |
Cytomap | 4q31.23 | |
Gene Type | protein-coding | GO ID | NA | UniProtAcc | A0A1B0GVH7 |
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Malignant transformation analysis |
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Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
285423 | IQCM | HTA11_3410_2000001011 | Human | Colorectum | AD | 2.26e-46 | -1.17e+00 | 0.0155 |
285423 | IQCM | HTA11_2487_2000001011 | Human | Colorectum | SER | 1.56e-19 | -8.87e-01 | -0.1808 |
285423 | IQCM | HTA11_2951_2000001011 | Human | Colorectum | AD | 1.23e-07 | -1.14e+00 | 0.0216 |
285423 | IQCM | HTA11_1938_2000001011 | Human | Colorectum | AD | 6.68e-16 | -1.05e+00 | -0.0811 |
285423 | IQCM | HTA11_78_2000001011 | Human | Colorectum | AD | 7.37e-04 | -4.40e-01 | -0.1088 |
285423 | IQCM | HTA11_3361_2000001011 | Human | Colorectum | AD | 2.53e-08 | -7.54e-01 | -0.1207 |
285423 | IQCM | HTA11_83_2000001011 | Human | Colorectum | SER | 2.08e-07 | -7.42e-01 | -0.1526 |
285423 | IQCM | HTA11_696_2000001011 | Human | Colorectum | AD | 1.06e-30 | -7.08e-01 | -0.1464 |
285423 | IQCM | HTA11_866_2000001011 | Human | Colorectum | AD | 2.47e-24 | -7.34e-01 | -0.1001 |
285423 | IQCM | HTA11_1391_2000001011 | Human | Colorectum | AD | 6.54e-33 | -1.04e+00 | -0.059 |
285423 | IQCM | HTA11_2992_2000001011 | Human | Colorectum | SER | 5.81e-03 | -8.52e-01 | -0.1706 |
285423 | IQCM | HTA11_5212_2000001011 | Human | Colorectum | AD | 1.50e-08 | -1.02e+00 | -0.2061 |
285423 | IQCM | HTA11_5216_2000001011 | Human | Colorectum | SER | 2.54e-05 | -9.94e-01 | -0.1462 |
285423 | IQCM | HTA11_546_2000001011 | Human | Colorectum | AD | 3.43e-07 | -8.19e-01 | -0.0842 |
285423 | IQCM | HTA11_7862_2000001011 | Human | Colorectum | AD | 3.36e-12 | -9.02e-01 | -0.0179 |
285423 | IQCM | HTA11_866_3004761011 | Human | Colorectum | AD | 2.46e-34 | -1.10e+00 | 0.096 |
285423 | IQCM | HTA11_4255_2000001011 | Human | Colorectum | SER | 3.11e-08 | -1.21e+00 | 0.0446 |
285423 | IQCM | HTA11_9408_2000001011 | Human | Colorectum | AD | 1.31e-05 | -1.15e+00 | 0.0451 |
285423 | IQCM | HTA11_8622_2000001021 | Human | Colorectum | SER | 1.30e-07 | -1.03e+00 | 0.0528 |
285423 | IQCM | HTA11_6801_2000001011 | Human | Colorectum | SER | 7.25e-07 | -1.13e+00 | 0.0171 |
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∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
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Malignant transformation related pathway analysis |
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Tissue | Disease Stage | Enriched GO biological Processes |
Stomach | WIM | ![]() |
Stomach | SIM | ![]() |
Liver | NAFLD | ![]() |
Liver | Cirrhotic | ![]() |
Liver | HCC | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
Page: 1 2 3 4 5 6 7 8 9 |
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GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
Page: 1 |
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Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
Page: 1 |
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Cell-cell communication analysis |
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Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
Page: 1 |
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Single-cell gene regulatory network inference analysis |
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TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
Page: 1 |
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Somatic mutation of malignant transformation related genes |
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Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
Page: 1 |
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Related drugs of malignant transformation related genes |
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(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
Page: 1 |