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Gene: CELA2B |
Gene summary for CELA2B |
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Gene information | Species | Human | Gene symbol | CELA2B | Gene ID | 51032 |
Gene name | chymotrypsin like elastase 2B | |
Gene Alias | ELA2B | |
Cytomap | 1p36.21 | |
Gene Type | protein-coding | GO ID | GO:0006508 | UniProtAcc | P08218 |
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Malignant transformation analysis |
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Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
51032 | CELA2B | HTA12-15-2 | Human | Pancreas | PDAC | 2.19e-09 | -1.21e+00 | 0.2315 |
51032 | CELA2B | HTA12-16-5 | Human | Pancreas | PDAC | 2.46e-05 | 5.02e-01 | 0.047 |
51032 | CELA2B | HTA12-16-6 | Human | Pancreas | PDAC | 4.13e-03 | 7.51e-01 | 0.0544 |
51032 | CELA2B | HTA12-23-1 | Human | Pancreas | PDAC | 2.64e-05 | -1.21e+00 | 0.3405 |
51032 | CELA2B | HTA12-25-1 | Human | Pancreas | PDAC | 4.01e-09 | -1.21e+00 | 0.313 |
51032 | CELA2B | HTA12-26-1 | Human | Pancreas | PDAC | 5.77e-12 | -1.21e+00 | 0.3728 |
51032 | CELA2B | HTA12-29-1 | Human | Pancreas | PDAC | 1.59e-37 | -1.21e+00 | 0.3722 |
51032 | CELA2B | HTA12-9-1 | Human | Pancreas | PDAC | 4.30e-16 | -1.14e+00 | 0.1532 |
51032 | CELA2B | HTA12-9-3 | Human | Pancreas | PDAC | 5.70e-07 | -1.21e+00 | 0.2045 |
51032 | CELA2B | 3829-EC | Human | Pancreas | PanIN | 1.11e-42 | -1.05e+00 | 0.009 |
51032 | CELA2B | 4347-EC | Human | Pancreas | PanIN | 2.26e-21 | -2.45e-01 | 0.0572 |
51032 | CELA2B | 4741-EC2 | Human | Pancreas | PanIN | 3.37e-10 | 3.74e-01 | 0.0194 |
51032 | CELA2B | 181429 | Human | Pancreas | PDAC | 4.05e-02 | -1.21e+00 | 0.1416 |
51032 | CELA2B | DS20191261Tumor | Human | Pancreas | PDAC | 3.23e-22 | -1.21e+00 | 0.1367 |
51032 | CELA2B | DS20191261TumorKeller | Human | Pancreas | PDAC | 1.37e-03 | -1.21e+00 | 0.1407 |
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Tissue | Expression Dynamics | Abbreviation |
∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
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Malignant transformation related pathway analysis |
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Tissue | Disease Stage | Enriched GO biological Processes |
Stomach | WIM | ![]() |
Stomach | SIM | ![]() |
Liver | NAFLD | ![]() |
Liver | Cirrhotic | ![]() |
Liver | HCC | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
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GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
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Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
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Cell-cell communication analysis |
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Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
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Single-cell gene regulatory network inference analysis |
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TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
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Somatic mutation of malignant transformation related genes |
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Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
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Related drugs of malignant transformation related genes |
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(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
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