GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
GO:0048875 | Lung | IAC | chemical homeostasis within a tissue | 11/2061 | 14/18723 | 7.44e-09 | 1.05e-06 | 11 |
GO:0043129 | Lung | IAC | surfactant homeostasis | 10/2061 | 12/18723 | 1.37e-08 | 1.77e-06 | 10 |
GO:00341018 | Lung | IAC | erythrocyte homeostasis | 34/2061 | 129/18723 | 8.85e-07 | 4.95e-05 | 34 |
GO:00302188 | Lung | IAC | erythrocyte differentiation | 32/2061 | 120/18723 | 1.39e-06 | 7.05e-05 | 32 |
GO:00022628 | Lung | IAC | myeloid cell homeostasis | 37/2061 | 157/18723 | 5.42e-06 | 2.09e-04 | 37 |
GO:00300998 | Lung | IAC | myeloid cell differentiation | 70/2061 | 381/18723 | 1.12e-05 | 3.45e-04 | 70 |
GO:00488728 | Lung | IAC | homeostasis of number of cells | 54/2061 | 272/18723 | 1.20e-05 | 3.64e-04 | 54 |
GO:00454443 | Lung | IAC | fat cell differentiation | 42/2061 | 229/18723 | 6.19e-04 | 8.50e-03 | 42 |
GO:00018947 | Lung | IAC | tissue homeostasis | 46/2061 | 268/18723 | 1.50e-03 | 1.60e-02 | 46 |
GO:00602497 | Lung | IAC | anatomical structure homeostasis | 51/2061 | 314/18723 | 2.91e-03 | 2.61e-02 | 51 |
GO:00488751 | Lung | AIS | chemical homeostasis within a tissue | 9/1849 | 14/18723 | 1.11e-06 | 7.51e-05 | 9 |
GO:00431291 | Lung | AIS | surfactant homeostasis | 8/1849 | 12/18723 | 3.07e-06 | 1.64e-04 | 8 |
GO:003410113 | Lung | AIS | erythrocyte homeostasis | 30/1849 | 129/18723 | 6.51e-06 | 2.92e-04 | 30 |
GO:003021813 | Lung | AIS | erythrocyte differentiation | 28/1849 | 120/18723 | 1.22e-05 | 4.71e-04 | 28 |
GO:003009913 | Lung | AIS | myeloid cell differentiation | 63/1849 | 381/18723 | 3.05e-05 | 9.70e-04 | 63 |
GO:000226213 | Lung | AIS | myeloid cell homeostasis | 32/1849 | 157/18723 | 5.57e-05 | 1.57e-03 | 32 |
GO:004887213 | Lung | AIS | homeostasis of number of cells | 47/1849 | 272/18723 | 1.03e-04 | 2.50e-03 | 47 |
GO:004544411 | Lung | AIS | fat cell differentiation | 37/1849 | 229/18723 | 1.88e-03 | 2.08e-02 | 37 |
GO:000189412 | Lung | AIS | tissue homeostasis | 41/1849 | 268/18723 | 3.13e-03 | 3.01e-02 | 41 |
GO:00431293 | Lung | MIAC | surfactant homeostasis | 6/967 | 12/18723 | 1.32e-05 | 9.85e-04 | 6 |
Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
ADGRF5 | SNV | Missense_Mutation | rs369061339 | c.2216C>T | p.Pro739Leu | p.P739L | Q8IZF2 | protein_coding | deleterious(0.02) | probably_damaging(0.999) | TCGA-A8-A07L-01 | Breast | breast invasive carcinoma | Female | <65 | III/IV | Chemotherapy | | CR |
ADGRF5 | SNV | Missense_Mutation | rs146250899 | c.1030G>A | p.Asp344Asn | p.D344N | Q8IZF2 | protein_coding | deleterious(0.04) | probably_damaging(0.964) | TCGA-AC-A23H-01 | Breast | breast invasive carcinoma | Female | >=65 | I/II | Unknown | Unknown | PD |
ADGRF5 | SNV | Missense_Mutation | | c.3129G>T | p.Lys1043Asn | p.K1043N | Q8IZF2 | protein_coding | tolerated(0.55) | possibly_damaging(0.52) | TCGA-AN-A046-01 | Breast | breast invasive carcinoma | Female | >=65 | I/II | Unknown | Unknown | SD |
ADGRF5 | SNV | Missense_Mutation | | c.2836A>G | p.Ser946Gly | p.S946G | Q8IZF2 | protein_coding | deleterious(0.03) | benign(0.01) | TCGA-BH-A0C7-01 | Breast | breast invasive carcinoma | Female | <65 | I/II | Chemotherapy | adriamycin | CR |
ADGRF5 | SNV | Missense_Mutation | | c.3148N>T | p.Arg1050Cys | p.R1050C | Q8IZF2 | protein_coding | deleterious(0) | probably_damaging(0.999) | TCGA-E9-A3QA-01 | Breast | breast invasive carcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
ADGRF5 | SNV | Missense_Mutation | | c.2227N>A | p.Glu743Lys | p.E743K | Q8IZF2 | protein_coding | tolerated(0.52) | benign(0) | TCGA-EW-A1J5-01 | Breast | breast invasive carcinoma | Female | <65 | I/II | Chemotherapy | adriamycin | SD |
ADGRF5 | SNV | Missense_Mutation | | c.919G>C | p.Glu307Gln | p.E307Q | Q8IZF2 | protein_coding | tolerated(0.32) | benign(0.038) | TCGA-GM-A2D9-01 | Breast | breast invasive carcinoma | Female | >=65 | I/II | Hormone Therapy | arimidex | SD |
ADGRF5 | SNV | Missense_Mutation | | c.1981N>G | p.Leu661Val | p.L661V | Q8IZF2 | protein_coding | tolerated(0.11) | benign(0.02) | TCGA-LD-A74U-01 | Breast | breast invasive carcinoma | Female | >=65 | III/IV | Chemotherapy | taxotere | SD |
ADGRF5 | SNV | Missense_Mutation | novel | c.2767N>C | p.Val923Leu | p.V923L | Q8IZF2 | protein_coding | tolerated(0.36) | benign(0.255) | TCGA-LL-A5YO-01 | Breast | breast invasive carcinoma | Female | <65 | I/II | Chemotherapy | taxotere | CR |
ADGRF5 | insertion | Frame_Shift_Ins | novel | c.1876_1877insCTTTGTTCTTCTCCTCTTTCTTTATACCAAATATGGTTTCG | p.Phe626SerfsTer46 | p.F626Sfs*46 | Q8IZF2 | protein_coding | | | TCGA-A8-A07J-01 | Breast | breast invasive carcinoma | Female | <65 | I/II | Chemotherapy | 5-fluorouracil | CR |