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Gene: SNHG10 |
Gene summary for SNHG10 |
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Gene information | Species | Human | Gene symbol | SNHG10 | Gene ID | 283596 |
Gene name | small nucleolar RNA host gene 10 | |
Gene Alias | C14orf62 | |
Cytomap | 14q32.13 | |
Gene Type | ncRNA | GO ID | GO:0006139 | UniProtAcc | NA |
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Malignant transformation analysis |
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Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
283596 | SNHG10 | LZE8T | Human | Esophagus | ESCC | 3.00e-02 | 5.01e-02 | 0.067 |
283596 | SNHG10 | LZE24T | Human | Esophagus | ESCC | 7.64e-08 | 2.66e-01 | 0.0596 |
283596 | SNHG10 | P1T-E | Human | Esophagus | ESCC | 1.16e-04 | 2.13e-01 | 0.0875 |
283596 | SNHG10 | P2T-E | Human | Esophagus | ESCC | 1.88e-06 | 1.55e-01 | 0.1177 |
283596 | SNHG10 | P4T-E | Human | Esophagus | ESCC | 1.70e-10 | 2.39e-01 | 0.1323 |
283596 | SNHG10 | P5T-E | Human | Esophagus | ESCC | 2.30e-05 | 6.35e-02 | 0.1327 |
283596 | SNHG10 | P8T-E | Human | Esophagus | ESCC | 9.44e-13 | 2.22e-01 | 0.0889 |
283596 | SNHG10 | P9T-E | Human | Esophagus | ESCC | 4.32e-04 | 1.39e-01 | 0.1131 |
283596 | SNHG10 | P10T-E | Human | Esophagus | ESCC | 2.83e-43 | 8.79e-01 | 0.116 |
283596 | SNHG10 | P11T-E | Human | Esophagus | ESCC | 4.16e-02 | 1.25e-01 | 0.1426 |
283596 | SNHG10 | P12T-E | Human | Esophagus | ESCC | 2.56e-09 | 2.90e-01 | 0.1122 |
283596 | SNHG10 | P15T-E | Human | Esophagus | ESCC | 1.11e-06 | 1.91e-01 | 0.1149 |
283596 | SNHG10 | P16T-E | Human | Esophagus | ESCC | 2.86e-03 | 1.19e-01 | 0.1153 |
283596 | SNHG10 | P21T-E | Human | Esophagus | ESCC | 1.29e-08 | 1.50e-01 | 0.1617 |
283596 | SNHG10 | P22T-E | Human | Esophagus | ESCC | 7.01e-09 | 2.12e-01 | 0.1236 |
283596 | SNHG10 | P23T-E | Human | Esophagus | ESCC | 1.19e-19 | 5.05e-01 | 0.108 |
283596 | SNHG10 | P24T-E | Human | Esophagus | ESCC | 1.66e-02 | 1.34e-01 | 0.1287 |
283596 | SNHG10 | P26T-E | Human | Esophagus | ESCC | 1.97e-13 | 3.97e-01 | 0.1276 |
283596 | SNHG10 | P27T-E | Human | Esophagus | ESCC | 3.64e-17 | 3.78e-01 | 0.1055 |
283596 | SNHG10 | P28T-E | Human | Esophagus | ESCC | 2.88e-12 | 2.82e-01 | 0.1149 |
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Tissue | Expression Dynamics | Abbreviation |
Esophagus | ![]() | ESCC: Esophageal squamous cell carcinoma |
HGIN: High-grade intraepithelial neoplasias | ||
LGIN: Low-grade intraepithelial neoplasias |
∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
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Malignant transformation related pathway analysis |
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Tissue | Disease Stage | Enriched GO biological Processes |
Colorectum | CRC | ![]() |
Stomach | GC | ![]() |
Stomach | CAG with IM | ![]() |
Stomach | CSG | ![]() |
Stomach | CAG | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
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GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
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Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
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Cell-cell communication analysis |
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Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
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Single-cell gene regulatory network inference analysis |
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TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
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Somatic mutation of malignant transformation related genes |
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Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
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Related drugs of malignant transformation related genes |
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(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
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