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Gene: SLC26A4-AS1 |
Gene summary for SLC26A4-AS1 |
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Gene information | Species | Human | Gene symbol | SLC26A4-AS1 | Gene ID | 286002 |
Gene name | SLC26A4 antisense RNA 1 | |
Gene Alias | SLC26A4-AS1 | |
Cytomap | 7q22.3 | |
Gene Type | ncRNA | GO ID | NA | UniProtAcc | NA |
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Malignant transformation analysis |
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Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
286002 | SLC26A4-AS1 | Adj_PTCwithHT_6 | Human | Thyroid | HT | 1.42e-30 | -1.01e+00 | 0.02 |
286002 | SLC26A4-AS1 | Adj_PTCwithHT_8 | Human | Thyroid | HT | 8.09e-08 | -6.43e-01 | 0.0267 |
286002 | SLC26A4-AS1 | PTCwithHT_1 | Human | Thyroid | HT | 5.41e-11 | -1.02e+00 | 0.0238 |
286002 | SLC26A4-AS1 | PTCwithHT_6 | Human | Thyroid | HT | 1.70e-34 | -1.01e+00 | 0.02 |
286002 | SLC26A4-AS1 | PTCwithHT_8 | Human | Thyroid | HT | 7.43e-28 | -9.63e-01 | 0.0351 |
286002 | SLC26A4-AS1 | PTCwithoutHT_2 | Human | Thyroid | PTC | 1.49e-30 | -1.00e+00 | 0.0419 |
286002 | SLC26A4-AS1 | PTCwithoutHT_4_2 | Human | Thyroid | PTC | 2.81e-03 | -9.28e-01 | 0.0455 |
286002 | SLC26A4-AS1 | PTCwithoutHT_7 | Human | Thyroid | PTC | 5.41e-11 | -1.02e+00 | 0.0381 |
286002 | SLC26A4-AS1 | male-WTA | Human | Thyroid | PTC | 1.25e-27 | -5.91e-01 | 0.1037 |
286002 | SLC26A4-AS1 | PTC01 | Human | Thyroid | PTC | 4.24e-34 | -8.92e-01 | 0.1899 |
286002 | SLC26A4-AS1 | PTC03 | Human | Thyroid | PTC | 1.38e-04 | -6.92e-01 | 0.1784 |
286002 | SLC26A4-AS1 | PTC04 | Human | Thyroid | PTC | 3.37e-13 | -7.94e-01 | 0.1927 |
286002 | SLC26A4-AS1 | PTC05 | Human | Thyroid | PTC | 1.30e-04 | -7.95e-01 | 0.2065 |
286002 | SLC26A4-AS1 | PTC06 | Human | Thyroid | PTC | 8.62e-19 | -7.87e-01 | 0.2057 |
286002 | SLC26A4-AS1 | PTC07 | Human | Thyroid | PTC | 4.69e-31 | -7.69e-01 | 0.2044 |
286002 | SLC26A4-AS1 | ATC08 | Human | Thyroid | ATC | 2.31e-08 | -9.66e-01 | 0.0541 |
286002 | SLC26A4-AS1 | ATC09 | Human | Thyroid | ATC | 1.51e-11 | -1.02e+00 | 0.2871 |
286002 | SLC26A4-AS1 | ATC11 | Human | Thyroid | ATC | 4.89e-02 | -1.02e+00 | 0.3386 |
286002 | SLC26A4-AS1 | ATC12 | Human | Thyroid | ATC | 6.62e-35 | -1.02e+00 | 0.34 |
286002 | SLC26A4-AS1 | ATC13 | Human | Thyroid | ATC | 5.57e-37 | -1.02e+00 | 0.34 |
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Tissue | Expression Dynamics | Abbreviation |
Thyroid | ![]() | ATC: Anaplastic thyroid cancer |
HT: Hashimoto's thyroiditis | ||
PTC: Papillary thyroid cancer |
∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
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Malignant transformation related pathway analysis |
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Tissue | Disease Stage | Enriched GO biological Processes |
Colorectum | CRC | ![]() |
Stomach | GC | ![]() |
Stomach | CAG with IM | ![]() |
Stomach | CSG | ![]() |
Stomach | CAG | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
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GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
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Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
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Cell-cell communication analysis |
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Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
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Single-cell gene regulatory network inference analysis |
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TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
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Somatic mutation of malignant transformation related genes |
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Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
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Related drugs of malignant transformation related genes |
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(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
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