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Gene: MIR99AHG |
Gene summary for MIR99AHG |
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Gene information | Species | Human | Gene symbol | MIR99AHG | Gene ID | 388815 |
Gene name | mir-99a-let-7c cluster host gene | |
Gene Alias | C21orf34 | |
Cytomap | 21q21.1 | |
Gene Type | ncRNA | GO ID | NA | UniProtAcc | NA |
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Malignant transformation analysis |
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Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
388815 | MIR99AHG | CCI_1 | Human | Cervix | CC | 4.30e-25 | 9.69e-01 | 0.528 |
388815 | MIR99AHG | CCI_2 | Human | Cervix | CC | 2.30e-10 | 4.53e-01 | 0.5249 |
388815 | MIR99AHG | CCI_3 | Human | Cervix | CC | 2.23e-38 | 1.49e+00 | 0.516 |
388815 | MIR99AHG | sample1 | Human | Cervix | CC | 2.17e-17 | 4.67e-01 | 0.0959 |
388815 | MIR99AHG | H2 | Human | Cervix | HSIL_HPV | 4.00e-05 | 1.43e-01 | 0.0632 |
388815 | MIR99AHG | T1 | Human | Cervix | CC | 2.90e-30 | 5.80e-01 | 0.0918 |
388815 | MIR99AHG | AEH-subject2 | Human | Endometrium | AEH | 1.10e-02 | 1.63e-02 | -0.2525 |
388815 | MIR99AHG | EEC-subject3 | Human | Endometrium | EEC | 1.19e-04 | -5.19e-02 | -0.2525 |
388815 | MIR99AHG | GSM5276935 | Human | Endometrium | EEC | 4.83e-03 | -1.25e-01 | -0.123 |
388815 | MIR99AHG | GSM6177620_NYU_UCEC1_lib1_lib1 | Human | Endometrium | EEC | 2.20e-05 | -1.53e-01 | -0.1869 |
388815 | MIR99AHG | GSM6177620_NYU_UCEC1_lib2_lib2 | Human | Endometrium | EEC | 1.64e-04 | -1.53e-01 | -0.1875 |
388815 | MIR99AHG | GSM6177620_NYU_UCEC1_lib3_lib3 | Human | Endometrium | EEC | 1.15e-05 | -1.53e-01 | -0.1883 |
388815 | MIR99AHG | GSM6177621_NYU_UCEC2_lib1_lib1 | Human | Endometrium | EEC | 1.89e-07 | -1.53e-01 | -0.1934 |
388815 | MIR99AHG | GSM6177622_NYU_UCEC3_lib1_lib1 | Human | Endometrium | EEC | 1.89e-07 | -1.53e-01 | -0.1917 |
388815 | MIR99AHG | GSM6177622_NYU_UCEC3_lib2_lib2 | Human | Endometrium | EEC | 4.40e-08 | -1.53e-01 | -0.1916 |
388815 | MIR99AHG | LZE3D | Human | Esophagus | HGIN | 7.42e-03 | 3.84e-01 | 0.0668 |
388815 | MIR99AHG | P2T-E | Human | Esophagus | ESCC | 1.12e-09 | -7.48e-02 | 0.1177 |
388815 | MIR99AHG | P4T-E | Human | Esophagus | ESCC | 2.73e-16 | 5.41e-01 | 0.1323 |
388815 | MIR99AHG | P5T-E | Human | Esophagus | ESCC | 2.63e-03 | -1.24e-01 | 0.1327 |
388815 | MIR99AHG | P8T-E | Human | Esophagus | ESCC | 6.19e-05 | 6.06e-03 | 0.0889 |
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∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
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Malignant transformation related pathway analysis |
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Tissue | Disease Stage | Enriched GO biological Processes |
Colorectum | CRC | ![]() |
Stomach | GC | ![]() |
Stomach | CAG with IM | ![]() |
Stomach | CSG | ![]() |
Stomach | CAG | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
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GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
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Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
Page: 1 |
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Cell-cell communication analysis |
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Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
Page: 1 |
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Single-cell gene regulatory network inference analysis |
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TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
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Somatic mutation of malignant transformation related genes |
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Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
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Related drugs of malignant transformation related genes |
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(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
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