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Gene: MIR646HG |
Gene summary for MIR646HG |
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Gene information | Species | Human | Gene symbol | MIR646HG | Gene ID | 284757 |
Gene name | MIR646 host gene | |
Gene Alias | MIR646HG | |
Cytomap | 20q13.33 | |
Gene Type | ncRNA | GO ID | NA | UniProtAcc | NA |
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Malignant transformation analysis |
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Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
284757 | MIR646HG | HTA11_3410_2000001011 | Human | Colorectum | AD | 4.88e-02 | -2.23e-01 | 0.0155 |
284757 | MIR646HG | HTA11_83_2000001011 | Human | Colorectum | SER | 1.43e-04 | 6.49e-01 | -0.1526 |
284757 | MIR646HG | HTA11_7696_3000711011 | Human | Colorectum | AD | 1.85e-02 | -2.29e-01 | 0.0674 |
284757 | MIR646HG | HTA11_99999970781_79442 | Human | Colorectum | MSS | 2.62e-02 | -2.14e-01 | 0.294 |
284757 | MIR646HG | A002-C-010 | Human | Colorectum | FAP | 2.07e-07 | -2.42e-01 | 0.242 |
284757 | MIR646HG | A001-C-207 | Human | Colorectum | FAP | 3.47e-02 | -2.29e-01 | 0.1278 |
284757 | MIR646HG | A002-C-203 | Human | Colorectum | FAP | 4.38e-06 | -2.38e-01 | 0.2786 |
284757 | MIR646HG | A001-C-108 | Human | Colorectum | FAP | 3.48e-03 | -2.10e-01 | -0.0272 |
284757 | MIR646HG | A002-C-205 | Human | Colorectum | FAP | 7.55e-04 | -2.15e-01 | -0.1236 |
284757 | MIR646HG | A015-C-006 | Human | Colorectum | FAP | 6.97e-04 | -2.45e-01 | -0.0994 |
284757 | MIR646HG | A002-C-114 | Human | Colorectum | FAP | 2.47e-05 | -2.45e-01 | -0.1561 |
284757 | MIR646HG | A015-C-104 | Human | Colorectum | FAP | 3.51e-02 | -1.64e-01 | -0.1899 |
284757 | MIR646HG | A002-C-016 | Human | Colorectum | FAP | 2.07e-07 | -2.45e-01 | 0.0521 |
284757 | MIR646HG | A008-E-015 | Human | Colorectum | FAP | 2.89e-24 | 8.10e-01 | 0.0177 |
284757 | MIR646HG | A014-C-008 | Human | Colorectum | FAP | 1.80e-03 | -2.45e-01 | -0.191 |
284757 | MIR646HG | A018-E-020 | Human | Colorectum | FAP | 7.65e-04 | -2.28e-01 | -0.2034 |
284757 | MIR646HG | F034 | Human | Colorectum | FAP | 2.05e-06 | -2.39e-01 | -0.0665 |
284757 | MIR646HG | F072B | Human | Colorectum | FAP | 4.25e-05 | -2.45e-01 | 0.257 |
284757 | MIR646HG | CRC-1-8810 | Human | Colorectum | CRC | 9.36e-06 | -2.42e-01 | 0.6257 |
284757 | MIR646HG | CRC-3-11773 | Human | Colorectum | CRC | 2.64e-04 | -2.35e-01 | 0.2564 |
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∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
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Malignant transformation related pathway analysis |
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Tissue | Disease Stage | Enriched GO biological Processes |
Colorectum | CRC | ![]() |
Stomach | GC | ![]() |
Stomach | CAG with IM | ![]() |
Stomach | CSG | ![]() |
Stomach | CAG | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
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GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
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Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
Page: 1 |
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Cell-cell communication analysis |
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Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
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Single-cell gene regulatory network inference analysis |
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TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
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Somatic mutation of malignant transformation related genes |
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Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
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Related drugs of malignant transformation related genes |
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(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
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