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Gene: LHFPL6 |
Gene summary for LHFPL6 |
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Gene information | Species | Human | Gene symbol | LHFPL6 | Gene ID | 10186 |
Gene name | LHFPL tetraspan subfamily member 6 | |
Gene Alias | LHFP | |
Cytomap | 13q13.3-q14.11 | |
Gene Type | protein-coding | GO ID | GO:0005575 | UniProtAcc | A0A024RDR1 |
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Malignant transformation analysis |
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Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
10186 | LHFPL6 | HTA11_3410_2000001011 | Human | Colorectum | AD | 6.18e-05 | 1.39e-01 | 0.0155 |
10186 | LHFPL6 | HTA11_2487_2000001011 | Human | Colorectum | SER | 9.70e-11 | 2.15e-01 | -0.1808 |
10186 | LHFPL6 | HTA11_2951_2000001011 | Human | Colorectum | AD | 1.54e-06 | 4.56e-01 | 0.0216 |
10186 | LHFPL6 | HTA11_1938_2000001011 | Human | Colorectum | AD | 4.99e-16 | 6.97e-01 | -0.0811 |
10186 | LHFPL6 | HTA11_78_2000001011 | Human | Colorectum | AD | 1.34e-07 | 3.44e-01 | -0.1088 |
10186 | LHFPL6 | HTA11_347_2000001011 | Human | Colorectum | AD | 4.49e-14 | 3.26e-01 | -0.1954 |
10186 | LHFPL6 | HTA11_3361_2000001011 | Human | Colorectum | AD | 9.62e-11 | 4.40e-01 | -0.1207 |
10186 | LHFPL6 | HTA11_83_2000001011 | Human | Colorectum | SER | 1.75e-08 | 3.00e-01 | -0.1526 |
10186 | LHFPL6 | HTA11_696_2000001011 | Human | Colorectum | AD | 9.57e-13 | 3.90e-01 | -0.1464 |
10186 | LHFPL6 | HTA11_866_2000001011 | Human | Colorectum | AD | 1.52e-07 | 2.17e-01 | -0.1001 |
10186 | LHFPL6 | HTA11_1391_2000001011 | Human | Colorectum | AD | 2.76e-10 | 2.80e-01 | -0.059 |
10186 | LHFPL6 | HTA11_866_3004761011 | Human | Colorectum | AD | 1.22e-20 | 4.56e-01 | 0.096 |
10186 | LHFPL6 | HTA11_4255_2000001011 | Human | Colorectum | SER | 1.33e-02 | 2.17e-01 | 0.0446 |
10186 | LHFPL6 | HTA11_9408_2000001011 | Human | Colorectum | AD | 2.97e-02 | 3.70e-01 | 0.0451 |
10186 | LHFPL6 | HTA11_7663_2000001011 | Human | Colorectum | SER | 1.36e-04 | 3.25e-01 | 0.0131 |
10186 | LHFPL6 | HTA11_10623_2000001011 | Human | Colorectum | AD | 7.05e-11 | 3.52e-01 | -0.0177 |
10186 | LHFPL6 | HTA11_6801_2000001011 | Human | Colorectum | SER | 3.26e-03 | 3.24e-01 | 0.0171 |
10186 | LHFPL6 | HTA11_10711_2000001011 | Human | Colorectum | AD | 1.99e-19 | 6.38e-01 | 0.0338 |
10186 | LHFPL6 | HTA11_7696_3000711011 | Human | Colorectum | AD | 5.94e-09 | 2.84e-01 | 0.0674 |
10186 | LHFPL6 | HTA11_6818_2000001011 | Human | Colorectum | AD | 3.42e-09 | 6.68e-01 | 0.0112 |
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∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
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Malignant transformation related pathway analysis |
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Tissue | Disease Stage | Enriched GO biological Processes |
Colorectum | CRC | ![]() |
Stomach | GC | ![]() |
Stomach | CAG with IM | ![]() |
Stomach | CSG | ![]() |
Stomach | CAG | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
Page: 1 2 3 4 5 6 7 8 9 |
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GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
Page: 1 |
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Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
Page: 1 |
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Cell-cell communication analysis |
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Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
Page: 1 |
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Single-cell gene regulatory network inference analysis |
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TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
Page: 1 |
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Somatic mutation of malignant transformation related genes |
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Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
Page: 1 |
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Related drugs of malignant transformation related genes |
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(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
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