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Gene: ICT1 |
Gene summary for ICT1 |
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Gene information | Species | Human | Gene symbol | ICT1 | Gene ID | 3396 |
Gene name | mitochondrial ribosomal protein L58 | |
Gene Alias | DS-1 | |
Cytomap | 17q25.1 | |
Gene Type | protein-coding | GO ID | GO:0006412 | UniProtAcc | Q14197 |
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Malignant transformation analysis |
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Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
3396 | ICT1 | P1T-E | Human | Esophagus | ESCC | 7.43e-09 | 3.82e-01 | 0.0875 |
3396 | ICT1 | P2T-E | Human | Esophagus | ESCC | 2.86e-20 | 3.85e-01 | 0.1177 |
3396 | ICT1 | P4T-E | Human | Esophagus | ESCC | 4.05e-24 | 5.18e-01 | 0.1323 |
3396 | ICT1 | P5T-E | Human | Esophagus | ESCC | 3.52e-19 | 3.23e-01 | 0.1327 |
3396 | ICT1 | P8T-E | Human | Esophagus | ESCC | 4.19e-25 | 4.98e-01 | 0.0889 |
3396 | ICT1 | P9T-E | Human | Esophagus | ESCC | 1.75e-19 | 4.35e-01 | 0.1131 |
3396 | ICT1 | P10T-E | Human | Esophagus | ESCC | 1.41e-52 | 7.63e-01 | 0.116 |
3396 | ICT1 | P11T-E | Human | Esophagus | ESCC | 1.44e-21 | 6.84e-01 | 0.1426 |
3396 | ICT1 | P12T-E | Human | Esophagus | ESCC | 1.49e-39 | 6.94e-01 | 0.1122 |
3396 | ICT1 | P15T-E | Human | Esophagus | ESCC | 5.20e-29 | 5.13e-01 | 0.1149 |
3396 | ICT1 | P16T-E | Human | Esophagus | ESCC | 3.60e-13 | 2.85e-01 | 0.1153 |
3396 | ICT1 | P17T-E | Human | Esophagus | ESCC | 4.56e-20 | 6.09e-01 | 0.1278 |
3396 | ICT1 | P19T-E | Human | Esophagus | ESCC | 2.95e-08 | 4.34e-01 | 0.1662 |
3396 | ICT1 | P20T-E | Human | Esophagus | ESCC | 2.44e-69 | 1.40e+00 | 0.1124 |
3396 | ICT1 | P21T-E | Human | Esophagus | ESCC | 2.49e-44 | 8.01e-01 | 0.1617 |
3396 | ICT1 | P22T-E | Human | Esophagus | ESCC | 1.15e-45 | 7.43e-01 | 0.1236 |
3396 | ICT1 | P23T-E | Human | Esophagus | ESCC | 5.34e-30 | 6.04e-01 | 0.108 |
3396 | ICT1 | P24T-E | Human | Esophagus | ESCC | 1.45e-46 | 8.27e-01 | 0.1287 |
3396 | ICT1 | P26T-E | Human | Esophagus | ESCC | 4.19e-25 | 5.29e-01 | 0.1276 |
3396 | ICT1 | P27T-E | Human | Esophagus | ESCC | 5.00e-17 | 3.14e-01 | 0.1055 |
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∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
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Malignant transformation related pathway analysis |
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Tissue | Disease Stage | Enriched GO biological Processes |
Colorectum | CRC | ![]() |
Stomach | GC | ![]() |
Stomach | CAG with IM | ![]() |
Stomach | CSG | ![]() |
Stomach | CAG | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
Page: 1 2 3 4 5 6 7 8 9 |
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GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
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Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
Page: 1 |
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Cell-cell communication analysis |
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Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
Page: 1 |
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Single-cell gene regulatory network inference analysis |
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TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
Page: 1 |
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Somatic mutation of malignant transformation related genes |
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Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
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Related drugs of malignant transformation related genes |
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(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
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