GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
GO:1903829113 | Thyroid | PTC | positive regulation of cellular protein localization | 162/5968 | 276/18723 | 2.40e-20 | 3.52e-18 | 162 |
GO:1902903113 | Thyroid | PTC | regulation of supramolecular fiber organization | 202/5968 | 383/18723 | 1.16e-17 | 1.15e-15 | 202 |
GO:0043254113 | Thyroid | PTC | regulation of protein-containing complex assembly | 215/5968 | 428/18723 | 1.23e-15 | 9.09e-14 | 215 |
GO:0072659112 | Thyroid | PTC | protein localization to plasma membrane | 153/5968 | 284/18723 | 9.90e-15 | 6.50e-13 | 153 |
GO:1990778111 | Thyroid | PTC | protein localization to cell periphery | 172/5968 | 333/18723 | 3.71e-14 | 2.30e-12 | 172 |
GO:00435437 | Thyroid | PTC | protein acylation | 134/5968 | 243/18723 | 4.22e-14 | 2.58e-12 | 134 |
GO:0051258113 | Thyroid | PTC | protein polymerization | 154/5968 | 297/18723 | 5.35e-13 | 2.66e-11 | 154 |
GO:0032271113 | Thyroid | PTC | regulation of protein polymerization | 123/5968 | 233/18723 | 2.45e-11 | 9.38e-10 | 123 |
GO:0030705111 | Thyroid | PTC | cytoskeleton-dependent intracellular transport | 104/5968 | 195/18723 | 3.87e-10 | 1.24e-08 | 104 |
GO:0010639112 | Thyroid | PTC | negative regulation of organelle organization | 163/5968 | 348/18723 | 3.04e-09 | 8.39e-08 | 163 |
GO:003010020 | Thyroid | PTC | regulation of endocytosis | 108/5968 | 211/18723 | 3.92e-09 | 1.04e-07 | 108 |
GO:007050717 | Thyroid | PTC | regulation of microtubule cytoskeleton organization | 80/5968 | 148/18723 | 1.79e-08 | 4.19e-07 | 80 |
GO:1904375111 | Thyroid | PTC | regulation of protein localization to cell periphery | 70/5968 | 125/18723 | 2.04e-08 | 4.71e-07 | 70 |
GO:190547525 | Thyroid | PTC | regulation of protein localization to membrane | 91/5968 | 175/18723 | 2.41e-08 | 5.43e-07 | 91 |
GO:004580720 | Thyroid | PTC | positive regulation of endocytosis | 58/5968 | 100/18723 | 6.11e-08 | 1.28e-06 | 58 |
GO:00109709 | Thyroid | PTC | transport along microtubule | 80/5968 | 155/18723 | 2.48e-07 | 4.32e-06 | 80 |
GO:1903076112 | Thyroid | PTC | regulation of protein localization to plasma membrane | 58/5968 | 104/18723 | 3.91e-07 | 6.51e-06 | 58 |
GO:004409110 | Thyroid | PTC | membrane biogenesis | 34/5968 | 55/18723 | 4.64e-06 | 5.69e-05 | 34 |
GO:00311229 | Thyroid | PTC | cytoplasmic microtubule organization | 34/5968 | 56/18723 | 8.20e-06 | 9.42e-05 | 34 |
GO:190547725 | Thyroid | PTC | positive regulation of protein localization to membrane | 55/5968 | 106/18723 | 1.45e-05 | 1.55e-04 | 55 |
Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
CLIP3 | SNV | Missense_Mutation | novel | c.748N>A | p.Glu250Lys | p.E250K | Q96DZ5 | protein_coding | deleterious(0.01) | benign(0.321) | TCGA-PE-A5DE-01 | Breast | breast invasive carcinoma | Female | <65 | I/II | Chemotherapy | taxotere | CR |
CLIP3 | SNV | Missense_Mutation | | c.1213C>G | p.Leu405Val | p.L405V | Q96DZ5 | protein_coding | tolerated(0.9) | benign(0) | TCGA-C5-A7UH-01 | Cervix | cervical & endocervical cancer | Female | <65 | III/IV | Chemotherapy | cisplatin | SD |
CLIP3 | SNV | Missense_Mutation | rs779187288 | c.461C>T | p.Thr154Met | p.T154M | Q96DZ5 | protein_coding | deleterious(0.02) | possibly_damaging(0.761) | TCGA-EA-A3HS-01 | Cervix | cervical & endocervical cancer | Female | <65 | I/II | Unknown | Unknown | SD |
CLIP3 | SNV | Missense_Mutation | rs750880445 | c.197C>T | p.Ala66Val | p.A66V | Q96DZ5 | protein_coding | tolerated(0.08) | possibly_damaging(0.834) | TCGA-EA-A3HU-01 | Cervix | cervical & endocervical cancer | Female | <65 | I/II | Unknown | Unknown | SD |
CLIP3 | SNV | Missense_Mutation | | c.343N>A | p.Gly115Arg | p.G115R | Q96DZ5 | protein_coding | deleterious(0.04) | probably_damaging(0.92) | TCGA-EX-A1H5-01 | Cervix | cervical & endocervical cancer | Female | <65 | I/II | Unknown | Unknown | SD |
CLIP3 | SNV | Missense_Mutation | rs370765485 | c.1298N>A | p.Arg433His | p.R433H | Q96DZ5 | protein_coding | deleterious(0.02) | benign(0.005) | TCGA-FU-A3HZ-01 | Cervix | cervical & endocervical cancer | Female | <65 | I/II | Chemotherapy | cisplatin | CR |
CLIP3 | SNV | Missense_Mutation | novel | c.143C>T | p.Pro48Leu | p.P48L | Q96DZ5 | protein_coding | tolerated(0.06) | benign(0.109) | TCGA-ZJ-AAXB-01 | Cervix | cervical & endocervical cancer | Female | <65 | I/II | Unknown | Unknown | SD |
CLIP3 | SNV | Missense_Mutation | novel | c.34N>A | p.Pro12Thr | p.P12T | Q96DZ5 | protein_coding | deleterious_low_confidence(0) | benign(0.031) | TCGA-ZJ-AB0I-01 | Cervix | cervical & endocervical cancer | Female | <65 | I/II | Unknown | Unknown | SD |
CLIP3 | SNV | Missense_Mutation | rs772399672 | c.443C>T | p.Ala148Val | p.A148V | Q96DZ5 | protein_coding | tolerated(0.26) | benign(0.193) | TCGA-5M-AAT6-01 | Colorectum | colon adenocarcinoma | Female | <65 | III/IV | Unknown | Unknown | PD |
CLIP3 | SNV | Missense_Mutation | rs757632653 | c.1550G>A | p.Arg517Gln | p.R517Q | Q96DZ5 | protein_coding | tolerated(0.09) | probably_damaging(0.953) | TCGA-A6-2675-01 | Colorectum | colon adenocarcinoma | Male | >=65 | I/II | Unknown | Unknown | SD |