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Gene: C2orf47 |
Gene summary for C2ORF47 |
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Gene information | Species | Human | Gene symbol | C2orf47 | Gene ID | 79568 |
Gene name | matrix AAA peptidase interacting protein 1 | |
Gene Alias | C2orf47 | |
Cytomap | 2q33.1 | |
Gene Type | protein-coding | GO ID | GO:0006810 | UniProtAcc | A0A024R3U8 |
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Malignant transformation analysis |
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Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
79568 | C2orf47 | P2T-E | Human | Esophagus | ESCC | 1.95e-20 | 2.51e-01 | 0.1177 |
79568 | C2orf47 | P4T-E | Human | Esophagus | ESCC | 5.08e-26 | 6.41e-01 | 0.1323 |
79568 | C2orf47 | P5T-E | Human | Esophagus | ESCC | 4.59e-14 | 3.34e-01 | 0.1327 |
79568 | C2orf47 | P8T-E | Human | Esophagus | ESCC | 2.22e-30 | 2.41e-01 | 0.0889 |
79568 | C2orf47 | P9T-E | Human | Esophagus | ESCC | 8.48e-12 | 2.37e-01 | 0.1131 |
79568 | C2orf47 | P10T-E | Human | Esophagus | ESCC | 2.39e-10 | 1.67e-01 | 0.116 |
79568 | C2orf47 | P11T-E | Human | Esophagus | ESCC | 1.87e-07 | 3.76e-01 | 0.1426 |
79568 | C2orf47 | P12T-E | Human | Esophagus | ESCC | 9.91e-20 | 4.90e-01 | 0.1122 |
79568 | C2orf47 | P15T-E | Human | Esophagus | ESCC | 4.20e-26 | 5.35e-01 | 0.1149 |
79568 | C2orf47 | P16T-E | Human | Esophagus | ESCC | 1.18e-16 | 2.88e-01 | 0.1153 |
79568 | C2orf47 | P17T-E | Human | Esophagus | ESCC | 7.06e-04 | 1.45e-01 | 0.1278 |
79568 | C2orf47 | P19T-E | Human | Esophagus | ESCC | 2.10e-04 | 3.57e-01 | 0.1662 |
79568 | C2orf47 | P20T-E | Human | Esophagus | ESCC | 7.60e-17 | 3.86e-01 | 0.1124 |
79568 | C2orf47 | P21T-E | Human | Esophagus | ESCC | 9.02e-23 | 4.27e-01 | 0.1617 |
79568 | C2orf47 | P22T-E | Human | Esophagus | ESCC | 5.56e-18 | 2.87e-01 | 0.1236 |
79568 | C2orf47 | P23T-E | Human | Esophagus | ESCC | 2.01e-26 | 3.84e-01 | 0.108 |
79568 | C2orf47 | P24T-E | Human | Esophagus | ESCC | 5.09e-20 | 4.17e-01 | 0.1287 |
79568 | C2orf47 | P26T-E | Human | Esophagus | ESCC | 5.05e-23 | 2.58e-01 | 0.1276 |
79568 | C2orf47 | P27T-E | Human | Esophagus | ESCC | 6.33e-19 | 1.91e-01 | 0.1055 |
79568 | C2orf47 | P28T-E | Human | Esophagus | ESCC | 2.13e-25 | 4.03e-01 | 0.1149 |
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∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
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Malignant transformation related pathway analysis |
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Tissue | Disease Stage | Enriched GO biological Processes |
Colorectum | CRC | ![]() |
Stomach | GC | ![]() |
Stomach | CAG with IM | ![]() |
Stomach | CSG | ![]() |
Stomach | CAG | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
Page: 1 2 3 4 5 6 7 8 9 |
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GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
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Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
Page: 1 |
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Cell-cell communication analysis |
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Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
Page: 1 |
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Single-cell gene regulatory network inference analysis |
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TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
Page: 1 |
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Somatic mutation of malignant transformation related genes |
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Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
Page: 1 |
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Related drugs of malignant transformation related genes |
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(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
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