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Gene: C11orf73 |
Gene summary for C11ORF73 |
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Gene information | Species | Human | Gene symbol | C11orf73 | Gene ID | 51501 |
Gene name | heat shock protein nuclear import factor hikeshi | |
Gene Alias | C11orf73 | |
Cytomap | 11q14.2 | |
Gene Type | protein-coding | GO ID | GO:0006606 | UniProtAcc | Q53FT3 |
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Malignant transformation analysis |
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Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
51501 | C11orf73 | P1T-E | Human | Esophagus | ESCC | 3.50e-13 | 5.10e-01 | 0.0875 |
51501 | C11orf73 | P2T-E | Human | Esophagus | ESCC | 1.31e-36 | 5.35e-01 | 0.1177 |
51501 | C11orf73 | P4T-E | Human | Esophagus | ESCC | 1.81e-80 | 1.47e+00 | 0.1323 |
51501 | C11orf73 | P5T-E | Human | Esophagus | ESCC | 3.65e-51 | 7.86e-01 | 0.1327 |
51501 | C11orf73 | P8T-E | Human | Esophagus | ESCC | 1.25e-26 | 4.32e-01 | 0.0889 |
51501 | C11orf73 | P9T-E | Human | Esophagus | ESCC | 5.10e-37 | 7.38e-01 | 0.1131 |
51501 | C11orf73 | P10T-E | Human | Esophagus | ESCC | 5.03e-64 | 9.49e-01 | 0.116 |
51501 | C11orf73 | P11T-E | Human | Esophagus | ESCC | 4.42e-38 | 1.05e+00 | 0.1426 |
51501 | C11orf73 | P12T-E | Human | Esophagus | ESCC | 1.14e-66 | 9.92e-01 | 0.1122 |
51501 | C11orf73 | P15T-E | Human | Esophagus | ESCC | 5.73e-37 | 6.54e-01 | 0.1149 |
51501 | C11orf73 | P16T-E | Human | Esophagus | ESCC | 1.57e-53 | 8.64e-01 | 0.1153 |
51501 | C11orf73 | P17T-E | Human | Esophagus | ESCC | 4.62e-31 | 1.06e+00 | 0.1278 |
51501 | C11orf73 | P19T-E | Human | Esophagus | ESCC | 3.00e-24 | 1.17e+00 | 0.1662 |
51501 | C11orf73 | P20T-E | Human | Esophagus | ESCC | 7.21e-33 | 5.94e-01 | 0.1124 |
51501 | C11orf73 | P21T-E | Human | Esophagus | ESCC | 2.27e-90 | 1.47e+00 | 0.1617 |
51501 | C11orf73 | P22T-E | Human | Esophagus | ESCC | 1.85e-55 | 8.42e-01 | 0.1236 |
51501 | C11orf73 | P23T-E | Human | Esophagus | ESCC | 9.45e-47 | 9.41e-01 | 0.108 |
51501 | C11orf73 | P24T-E | Human | Esophagus | ESCC | 7.32e-38 | 6.70e-01 | 0.1287 |
51501 | C11orf73 | P26T-E | Human | Esophagus | ESCC | 4.71e-53 | 8.91e-01 | 0.1276 |
51501 | C11orf73 | P27T-E | Human | Esophagus | ESCC | 3.65e-51 | 7.55e-01 | 0.1055 |
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∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
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Malignant transformation related pathway analysis |
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Tissue | Disease Stage | Enriched GO biological Processes |
Colorectum | CRC | ![]() |
Stomach | GC | ![]() |
Stomach | CAG with IM | ![]() |
Stomach | CSG | ![]() |
Stomach | CAG | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
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GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
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Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
Page: 1 |
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Cell-cell communication analysis |
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Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
Page: 1 |
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Single-cell gene regulatory network inference analysis |
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TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
Page: 1 |
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Somatic mutation of malignant transformation related genes |
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Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
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Related drugs of malignant transformation related genes |
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(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
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