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Gene: RPS19BP1 |
Gene summary for RPS19BP1 |
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Gene information | Species | Human | Gene symbol | RPS19BP1 | Gene ID | 91582 |
Gene name | ribosomal protein S19 binding protein 1 | |
Gene Alias | AROS | |
Cytomap | 22q13.1 | |
Gene Type | protein-coding | GO ID | GO:0005575 | UniProtAcc | A0A024R1T1 |
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Malignant transformation analysis |
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Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
91582 | RPS19BP1 | cSCC_p9 | Human | Skin | cSCC | 3.47e-06 | -1.04e-02 | -0.1991 |
91582 | RPS19BP1 | Pat01-B | Human | Stomach | GC | 3.15e-08 | 1.93e-01 | 0.5754 |
91582 | RPS19BP1 | Pat02-B | Human | Stomach | GC | 7.91e-37 | 4.28e-01 | 0.0368 |
91582 | RPS19BP1 | Pat03-B | Human | Stomach | GC | 5.43e-12 | 2.87e-01 | 0.3693 |
91582 | RPS19BP1 | Pat04-B | Human | Stomach | GC | 1.35e-23 | 4.83e-01 | -0.1483 |
91582 | RPS19BP1 | Pat05-B | Human | Stomach | GC | 8.17e-09 | 3.70e-01 | -0.0353 |
91582 | RPS19BP1 | Pat06-B | Human | Stomach | GC | 2.06e-55 | 6.66e-01 | -0.1961 |
91582 | RPS19BP1 | Pat07-B | Human | Stomach | GC | 3.74e-02 | 2.77e-01 | 0.0935 |
91582 | RPS19BP1 | Pat09-B | Human | Stomach | GC | 1.99e-05 | 2.79e-01 | -0.0359 |
91582 | RPS19BP1 | Pat11-B | Human | Stomach | GC | 1.39e-17 | 5.26e-01 | -0.182 |
91582 | RPS19BP1 | Pat12-B | Human | Stomach | GC | 5.68e-20 | 3.35e-01 | 0.0325 |
91582 | RPS19BP1 | Pat13-B | Human | Stomach | GC | 6.15e-08 | 3.09e-01 | 0.0555 |
91582 | RPS19BP1 | Pat15-B | Human | Stomach | GC | 1.50e-21 | 4.62e-01 | -0.0778 |
91582 | RPS19BP1 | Pat16-B | Human | Stomach | GC | 3.90e-11 | 3.44e-01 | 0.1918 |
91582 | RPS19BP1 | Pat17-B | Human | Stomach | GC | 4.42e-10 | 3.43e-01 | 0.3109 |
91582 | RPS19BP1 | Pat18-B | Human | Stomach | GC | 2.96e-11 | 2.16e-01 | -0.0432 |
91582 | RPS19BP1 | Pat19-B | Human | Stomach | GC | 8.42e-08 | 2.24e-01 | 0.0826 |
91582 | RPS19BP1 | Pat22-B | Human | Stomach | GC | 1.93e-36 | 4.83e-01 | -0.1042 |
91582 | RPS19BP1 | Pat24-B | Human | Stomach | GC | 6.62e-17 | 4.73e-01 | -0.1184 |
91582 | RPS19BP1 | Pat25-A | Human | Stomach | CAG with IM | 6.28e-43 | 4.83e-01 | -0.1648 |
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∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
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Malignant transformation related pathway analysis |
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Tissue | Disease Stage | Enriched GO biological Processes |
Colorectum | AD | ![]() |
Colorectum | SER | ![]() |
Colorectum | MSS | ![]() |
Colorectum | MSI-H | ![]() |
Colorectum | FAP | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
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GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
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Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
Page: 1 |
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Cell-cell communication analysis |
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Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
Page: 1 |
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Single-cell gene regulatory network inference analysis |
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TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
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Somatic mutation of malignant transformation related genes |
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Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
RPS19BP1 | SNV | Missense_Mutation | novel | c.135N>C | p.Gln45His | p.Q45H | Q86WX3 | protein_coding | tolerated(0.11) | benign(0.281) | TCGA-JW-A5VL-01 | Cervix | cervical & endocervical cancer | Female | <65 | I/II | Unknown | Unknown | SD |
RPS19BP1 | SNV | Missense_Mutation | novel | c.306N>T | p.Lys102Asn | p.K102N | Q86WX3 | protein_coding | deleterious(0) | probably_damaging(0.988) | TCGA-AA-3947-01 | Colorectum | colon adenocarcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
RPS19BP1 | SNV | Missense_Mutation | novel | c.245N>T | p.Thr82Met | p.T82M | Q86WX3 | protein_coding | tolerated(0.15) | benign(0.003) | TCGA-A5-A0G1-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | >=65 | I/II | Unknown | Unknown | SD |
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Related drugs of malignant transformation related genes |
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(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
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