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Gene: RPS19BP1 |
Gene summary for RPS19BP1 |
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Gene information | Species | Human | Gene symbol | RPS19BP1 | Gene ID | 91582 |
Gene name | ribosomal protein S19 binding protein 1 | |
Gene Alias | AROS | |
Cytomap | 22q13.1 | |
Gene Type | protein-coding | GO ID | GO:0005575 | UniProtAcc | A0A024R1T1 |
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Malignant transformation analysis |
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Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
91582 | RPS19BP1 | P83T-E | Human | Esophagus | ESCC | 1.83e-76 | 2.99e+00 | 0.1738 |
91582 | RPS19BP1 | P84T-E | Human | Esophagus | ESCC | 2.45e-15 | 1.45e+00 | 0.0933 |
91582 | RPS19BP1 | P89T-E | Human | Esophagus | ESCC | 1.34e-29 | 2.61e+00 | 0.1752 |
91582 | RPS19BP1 | P91T-E | Human | Esophagus | ESCC | 1.93e-20 | 2.34e+00 | 0.1828 |
91582 | RPS19BP1 | P94T-E | Human | Esophagus | ESCC | 4.29e-04 | 1.39e+00 | 0.0879 |
91582 | RPS19BP1 | P104T-E | Human | Esophagus | ESCC | 1.67e-02 | 7.53e-01 | 0.0931 |
91582 | RPS19BP1 | P107T-E | Human | Esophagus | ESCC | 2.44e-69 | 1.49e+00 | 0.171 |
91582 | RPS19BP1 | P126T-E | Human | Esophagus | ESCC | 5.32e-12 | 1.51e+00 | 0.1125 |
91582 | RPS19BP1 | P127T-E | Human | Esophagus | ESCC | 1.46e-28 | 6.42e-01 | 0.0826 |
91582 | RPS19BP1 | P128T-E | Human | Esophagus | ESCC | 1.39e-67 | 2.78e+00 | 0.1241 |
91582 | RPS19BP1 | P130T-E | Human | Esophagus | ESCC | 4.67e-111 | 2.41e+00 | 0.1676 |
91582 | RPS19BP1 | S43 | Human | Liver | Cirrhotic | 4.16e-11 | -3.03e-01 | -0.0187 |
91582 | RPS19BP1 | HCC1_Meng | Human | Liver | HCC | 3.94e-73 | 4.50e-01 | 0.0246 |
91582 | RPS19BP1 | HCC2_Meng | Human | Liver | HCC | 1.47e-46 | 1.04e-01 | 0.0107 |
91582 | RPS19BP1 | cirrhotic1 | Human | Liver | Cirrhotic | 8.41e-17 | 3.24e-01 | 0.0202 |
91582 | RPS19BP1 | cirrhotic2 | Human | Liver | Cirrhotic | 1.25e-27 | 4.02e-01 | 0.0201 |
91582 | RPS19BP1 | cirrhotic3 | Human | Liver | Cirrhotic | 1.17e-23 | 3.68e-01 | 0.0215 |
91582 | RPS19BP1 | HCC1 | Human | Liver | HCC | 1.08e-05 | 3.85e+00 | 0.5336 |
91582 | RPS19BP1 | HCC2 | Human | Liver | HCC | 2.29e-31 | 5.43e+00 | 0.5341 |
91582 | RPS19BP1 | Pt13.b | Human | Liver | HCC | 4.18e-34 | 3.07e-01 | 0.0251 |
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∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
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Malignant transformation related pathway analysis |
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Tissue | Disease Stage | Enriched GO biological Processes |
Colorectum | AD | ![]() |
Colorectum | SER | ![]() |
Colorectum | MSS | ![]() |
Colorectum | MSI-H | ![]() |
Colorectum | FAP | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
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GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
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Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
Page: 1 |
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Cell-cell communication analysis |
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Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
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Single-cell gene regulatory network inference analysis |
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TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
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Somatic mutation of malignant transformation related genes |
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Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
RPS19BP1 | SNV | Missense_Mutation | novel | c.135N>C | p.Gln45His | p.Q45H | Q86WX3 | protein_coding | tolerated(0.11) | benign(0.281) | TCGA-JW-A5VL-01 | Cervix | cervical & endocervical cancer | Female | <65 | I/II | Unknown | Unknown | SD |
RPS19BP1 | SNV | Missense_Mutation | novel | c.306N>T | p.Lys102Asn | p.K102N | Q86WX3 | protein_coding | deleterious(0) | probably_damaging(0.988) | TCGA-AA-3947-01 | Colorectum | colon adenocarcinoma | Female | <65 | I/II | Unknown | Unknown | SD |
RPS19BP1 | SNV | Missense_Mutation | novel | c.245N>T | p.Thr82Met | p.T82M | Q86WX3 | protein_coding | tolerated(0.15) | benign(0.003) | TCGA-A5-A0G1-01 | Endometrium | uterine corpus endometrioid carcinoma | Female | >=65 | I/II | Unknown | Unknown | SD |
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Related drugs of malignant transformation related genes |
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(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
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