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Gene: SELM |
Gene summary for SELM |
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Gene information | Species | Human | Gene symbol | SELM | Gene ID | 140606 |
Gene name | selenoprotein M | |
Gene Alias | SELM | |
Cytomap | 22q12.2 | |
Gene Type | protein-coding | GO ID | GO:0003008 | UniProtAcc | Q8WWX9 |
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Malignant transformation analysis |
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Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
140606 | SELM | P1T-E | Human | Esophagus | ESCC | 2.39e-06 | 1.07e+00 | 0.0875 |
140606 | SELM | P2T-E | Human | Esophagus | ESCC | 1.98e-53 | 1.09e+00 | 0.1177 |
140606 | SELM | P4T-E | Human | Esophagus | ESCC | 5.46e-38 | 1.60e+00 | 0.1323 |
140606 | SELM | P5T-E | Human | Esophagus | ESCC | 3.20e-30 | 1.27e+00 | 0.1327 |
140606 | SELM | P8T-E | Human | Esophagus | ESCC | 1.58e-21 | 6.29e-01 | 0.0889 |
140606 | SELM | P9T-E | Human | Esophagus | ESCC | 8.62e-35 | 1.82e+00 | 0.1131 |
140606 | SELM | P10T-E | Human | Esophagus | ESCC | 1.73e-08 | 5.00e-01 | 0.116 |
140606 | SELM | P11T-E | Human | Esophagus | ESCC | 3.37e-47 | 2.21e+00 | 0.1426 |
140606 | SELM | P12T-E | Human | Esophagus | ESCC | 6.02e-58 | 1.11e+00 | 0.1122 |
140606 | SELM | P15T-E | Human | Esophagus | ESCC | 2.19e-17 | 9.04e-01 | 0.1149 |
140606 | SELM | P16T-E | Human | Esophagus | ESCC | 1.21e-70 | 1.59e+00 | 0.1153 |
140606 | SELM | P17T-E | Human | Esophagus | ESCC | 9.55e-16 | 1.35e+00 | 0.1278 |
140606 | SELM | P19T-E | Human | Esophagus | ESCC | 2.41e-20 | 3.00e+00 | 0.1662 |
140606 | SELM | P20T-E | Human | Esophagus | ESCC | 9.79e-32 | 1.25e+00 | 0.1124 |
140606 | SELM | P21T-E | Human | Esophagus | ESCC | 1.60e-96 | 2.09e+00 | 0.1617 |
140606 | SELM | P22T-E | Human | Esophagus | ESCC | 7.11e-65 | 1.53e+00 | 0.1236 |
140606 | SELM | P23T-E | Human | Esophagus | ESCC | 2.90e-24 | 1.57e+00 | 0.108 |
140606 | SELM | P24T-E | Human | Esophagus | ESCC | 5.61e-83 | 2.10e+00 | 0.1287 |
140606 | SELM | P26T-E | Human | Esophagus | ESCC | 4.59e-96 | 1.92e+00 | 0.1276 |
140606 | SELM | P27T-E | Human | Esophagus | ESCC | 1.65e-12 | 5.85e-01 | 0.1055 |
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∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
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Malignant transformation related pathway analysis |
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Tissue | Disease Stage | Enriched GO biological Processes |
Colorectum | AD | ![]() |
Colorectum | SER | ![]() |
Colorectum | MSS | ![]() |
Colorectum | MSI-H | ![]() |
Colorectum | FAP | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
Page: 1 2 3 4 5 6 7 8 9 |
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GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
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Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
Page: 1 |
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Cell-cell communication analysis |
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Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
Page: 1 |
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Single-cell gene regulatory network inference analysis |
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TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
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Somatic mutation of malignant transformation related genes |
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Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
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Related drugs of malignant transformation related genes |
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(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
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