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Gene: CECR5 |
Gene summary for CECR5 |
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Gene information | Species | Human | Gene symbol | CECR5 | Gene ID | 27440 |
Gene name | haloacid dehalogenase like hydrolase domain containing 5 | |
Gene Alias | CECR5 | |
Cytomap | 22q11.1 | |
Gene Type | protein-coding | GO ID | GO:0006629 | UniProtAcc | Q9BXW7 |
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Malignant transformation analysis |
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Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
27440 | CECR5 | SYSMH6 | Human | Oral cavity | OSCC | 1.25e-03 | 1.82e-01 | 0.1275 |
27440 | CECR5 | P1_cSCC | Human | Skin | cSCC | 3.07e-25 | 6.59e-01 | 0.0292 |
27440 | CECR5 | P2_cSCC | Human | Skin | cSCC | 6.48e-27 | 5.64e-01 | -0.024 |
27440 | CECR5 | P4_cSCC | Human | Skin | cSCC | 2.74e-28 | 5.72e-01 | -0.00290000000000005 |
27440 | CECR5 | P10_cSCC | Human | Skin | cSCC | 2.34e-27 | 6.38e-01 | 0.1017 |
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∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
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Malignant transformation related pathway analysis |
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Tissue | Disease Stage | Enriched GO biological Processes |
Colorectum | AD | ![]() |
Colorectum | SER | ![]() |
Colorectum | MSS | ![]() |
Colorectum | MSI-H | ![]() |
Colorectum | FAP | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
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GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
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Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
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Cell-cell communication analysis |
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Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
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Single-cell gene regulatory network inference analysis |
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TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
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Somatic mutation of malignant transformation related genes |
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Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
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Related drugs of malignant transformation related genes |
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(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
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