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Gene: AGAP2-AS1 |
Gene summary for AGAP2-AS1 |
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Gene information | Species | Human | Gene symbol | AGAP2-AS1 | Gene ID | 100130776 |
Gene name | AGAP2 antisense RNA 1 | |
Gene Alias | PUNISHER | |
Cytomap | 12q14.1 | |
Gene Type | ncRNA | GO ID | NA | UniProtAcc | NA |
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Malignant transformation analysis |
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Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
100130776 | AGAP2-AS1 | C30 | Human | Oral cavity | OSCC | 1.60e-44 | 1.80e+00 | 0.3055 |
100130776 | AGAP2-AS1 | C38 | Human | Oral cavity | OSCC | 1.99e-06 | 6.73e-01 | 0.172 |
100130776 | AGAP2-AS1 | C43 | Human | Oral cavity | OSCC | 1.81e-14 | 3.17e-01 | 0.1704 |
100130776 | AGAP2-AS1 | C46 | Human | Oral cavity | OSCC | 8.20e-06 | 2.37e-01 | 0.1673 |
100130776 | AGAP2-AS1 | C51 | Human | Oral cavity | OSCC | 8.93e-10 | 5.31e-01 | 0.2674 |
100130776 | AGAP2-AS1 | C06 | Human | Oral cavity | OSCC | 9.22e-04 | 6.96e-01 | 0.2699 |
100130776 | AGAP2-AS1 | C07 | Human | Oral cavity | OSCC | 9.41e-07 | 9.80e-01 | 0.2491 |
100130776 | AGAP2-AS1 | C08 | Human | Oral cavity | OSCC | 3.80e-32 | 7.16e-01 | 0.1919 |
100130776 | AGAP2-AS1 | C09 | Human | Oral cavity | OSCC | 3.01e-02 | 1.08e-01 | 0.1431 |
100130776 | AGAP2-AS1 | LP17 | Human | Oral cavity | LP | 4.52e-04 | 5.63e-01 | 0.2349 |
100130776 | AGAP2-AS1 | SYSMH1 | Human | Oral cavity | OSCC | 8.14e-11 | 2.84e-01 | 0.1127 |
100130776 | AGAP2-AS1 | SYSMH2 | Human | Oral cavity | OSCC | 7.22e-16 | 4.70e-01 | 0.2326 |
100130776 | AGAP2-AS1 | SYSMH3 | Human | Oral cavity | OSCC | 1.96e-12 | 2.91e-01 | 0.2442 |
100130776 | AGAP2-AS1 | P1_cSCC | Human | Skin | cSCC | 3.50e-16 | 6.27e-01 | 0.0292 |
100130776 | AGAP2-AS1 | P2_cSCC | Human | Skin | cSCC | 2.84e-12 | 4.35e-01 | -0.024 |
100130776 | AGAP2-AS1 | P4_cSCC | Human | Skin | cSCC | 9.49e-17 | 3.84e-01 | -0.00290000000000005 |
100130776 | AGAP2-AS1 | P10_cSCC | Human | Skin | cSCC | 1.89e-09 | 3.77e-01 | 0.1017 |
100130776 | AGAP2-AS1 | cSCC_p9 | Human | Skin | cSCC | 4.37e-03 | 8.51e-02 | -0.1991 |
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∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
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Malignant transformation related pathway analysis |
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Tissue | Disease Stage | Enriched GO biological Processes |
Colorectum | AD | ![]() |
Colorectum | SER | ![]() |
Colorectum | MSS | ![]() |
Colorectum | MSI-H | ![]() |
Colorectum | FAP | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
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GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
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Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
Page: 1 |
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Cell-cell communication analysis |
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Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
Page: 1 |
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Single-cell gene regulatory network inference analysis |
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TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
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Somatic mutation of malignant transformation related genes |
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Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
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Related drugs of malignant transformation related genes |
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(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
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