![]() |
|||||
|
![]() | |
![]() | |
![]() | |
![]() | |
![]() | |
![]() | |
![]() |
Gene: UNC5B-AS1 |
Gene summary for UNC5B-AS1 |
![]() |
Gene information | Species | Human | Gene symbol | UNC5B-AS1 | Gene ID | 728978 |
Gene name | UNC5B antisense RNA 1 | |
Gene Alias | UASR1 | |
Cytomap | 10q22.1 | |
Gene Type | ncRNA | GO ID | NA | UniProtAcc | NA |
Top |
Malignant transformation analysis |
![]() |
![]() |
Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
728978 | UNC5B-AS1 | C57 | Human | Oral cavity | OSCC | 8.90e-18 | 6.49e-01 | 0.1679 |
728978 | UNC5B-AS1 | C08 | Human | Oral cavity | OSCC | 4.14e-10 | 2.59e-01 | 0.1919 |
728978 | UNC5B-AS1 | C09 | Human | Oral cavity | OSCC | 1.83e-09 | 2.25e-01 | 0.1431 |
728978 | UNC5B-AS1 | LN22 | Human | Oral cavity | OSCC | 1.35e-07 | 6.10e-01 | 0.1733 |
728978 | UNC5B-AS1 | LN46 | Human | Oral cavity | OSCC | 3.87e-03 | 1.24e-01 | 0.1666 |
728978 | UNC5B-AS1 | SYSMH1 | Human | Oral cavity | OSCC | 5.84e-38 | 7.84e-01 | 0.1127 |
728978 | UNC5B-AS1 | SYSMH2 | Human | Oral cavity | OSCC | 4.27e-09 | 3.42e-01 | 0.2326 |
728978 | UNC5B-AS1 | SYSMH3 | Human | Oral cavity | OSCC | 1.77e-03 | 1.17e-01 | 0.2442 |
728978 | UNC5B-AS1 | SYSMH4 | Human | Oral cavity | OSCC | 9.33e-08 | 1.67e-01 | 0.1226 |
728978 | UNC5B-AS1 | SYSMH6 | Human | Oral cavity | OSCC | 7.87e-03 | 1.29e-01 | 0.1275 |
Page: 1 2 3 |
![]() |
∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
Top |
Malignant transformation related pathway analysis |
![]() |
![]() |
Tissue | Disease Stage | Enriched GO biological Processes |
Colorectum | AD | ![]() |
Colorectum | SER | ![]() |
Colorectum | MSS | ![]() |
Colorectum | MSI-H | ![]() |
Colorectum | FAP | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
Page: 1 2 3 4 5 6 7 8 9 |
![]() |
GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
Page: 1 |
![]() |
Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
Page: 1 |
Top |
Cell-cell communication analysis |
![]() |
Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
Page: 1 |
Top |
Single-cell gene regulatory network inference analysis |
![]() |
TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
Page: 1 |
Top |
Somatic mutation of malignant transformation related genes |
![]() |
Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
Page: 1 |
Top |
Related drugs of malignant transformation related genes |
![]() |
(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
Page: 1 |