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Gene: SMIM30 |
Gene summary for SMIM30 |
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Gene information | Species | Human | Gene symbol | SMIM30 | Gene ID | 401397 |
Gene name | small integral membrane protein 30 | |
Gene Alias | LINC00998 | |
Cytomap | 7q31.1 | |
Gene Type | protein-coding | GO ID | GO:0005575 | UniProtAcc | NA |
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Malignant transformation analysis |
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Entrez ID | Symbol | Replicates | Species | Organ | Tissue | Adj P-value | Log2FC | Malignancy |
401397 | SMIM30 | PTC05 | Human | Thyroid | PTC | 1.02e-26 | 9.68e-01 | 0.2065 |
401397 | SMIM30 | PTC06 | Human | Thyroid | PTC | 5.02e-46 | 8.74e-01 | 0.2057 |
401397 | SMIM30 | PTC07 | Human | Thyroid | PTC | 1.21e-51 | 8.34e-01 | 0.2044 |
401397 | SMIM30 | ATC09 | Human | Thyroid | ATC | 9.00e-08 | 3.31e-01 | 0.2871 |
401397 | SMIM30 | ATC11 | Human | Thyroid | ATC | 9.94e-09 | 5.05e-01 | 0.3386 |
401397 | SMIM30 | ATC12 | Human | Thyroid | ATC | 1.68e-15 | 3.82e-01 | 0.34 |
401397 | SMIM30 | ATC13 | Human | Thyroid | ATC | 7.43e-16 | 2.95e-01 | 0.34 |
401397 | SMIM30 | ATC1 | Human | Thyroid | ATC | 7.57e-09 | 3.83e-01 | 0.2878 |
401397 | SMIM30 | ATC2 | Human | Thyroid | ATC | 4.17e-22 | 1.51e+00 | 0.34 |
401397 | SMIM30 | ATC3 | Human | Thyroid | ATC | 5.97e-08 | 3.73e-01 | 0.338 |
401397 | SMIM30 | ATC4 | Human | Thyroid | ATC | 5.41e-21 | 5.16e-01 | 0.34 |
401397 | SMIM30 | ATC5 | Human | Thyroid | ATC | 7.43e-16 | 3.17e-01 | 0.34 |
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∗log2FC in expression of this searched gene in stem-like cells from each diseased tissue sample relative to stem-like cells in normal samples in each tissue plotted against the malignancy continuum. Samples are colored based on if they are from different disease stage. |
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Malignant transformation related pathway analysis |
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Tissue | Disease Stage | Enriched GO biological Processes |
Colorectum | AD | ![]() |
Colorectum | SER | ![]() |
Colorectum | MSS | ![]() |
Colorectum | MSI-H | ![]() |
Colorectum | FAP | ![]() |
∗Top 15 enriched GO BP terms are showed in the bar plot of each disease state in each tissue. Each row represents a significant GO biological process which is colored according to the -log10(p.adjust). |
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GO ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | Count |
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Pathway ID | Tissue | Disease Stage | Description | Gene Ratio | Bg Ratio | pvalue | p.adjust | qvalue | Count |
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Cell-cell communication analysis |
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Ligand | Receptor | LRpair | Pathway | Tissue | Disease Stage |
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Single-cell gene regulatory network inference analysis |
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TF | Cell Type | Tissue | Disease Stage | Target Gene | RSS | Regulon Activity |
∗The dot plots of a searched regulon are shown for all cell subpopulations in each disease state of each tissue based on the regulon specific score inferred using pySCENIC and by calculating the average expression. |
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Somatic mutation of malignant transformation related genes |
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Hugo Symbol | Variant Class | Variant Classification | dbSNP RS | HGVSc | HGVSp | HGVSp Short | SWISSPROT | BIOTYPE | SIFT | PolyPhen | Tumor Sample Barcode | Tissue | Histology | Sex | Age | Stage | Therapy Types | Drugs | Outcome |
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Related drugs of malignant transformation related genes |
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(DGIdb 4.0) |
Entrez ID | Symbol | Category | Interaction Types | Drug Claim Name | Drug Name | PMIDs |
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